Have a personal or library account? Click to login
Potential Gastric Cancer Immunotherapy: Stimulating the Immune System with Helicobacter pylori pIRES2-DsRed-Express-ureF DNA Vaccines Cover

Potential Gastric Cancer Immunotherapy: Stimulating the Immune System with Helicobacter pylori pIRES2-DsRed-Express-ureF DNA Vaccines

Open Access
|Feb 2024

References

  1. Baldari CT, Lanzavecchia A, Telford JL (2005) Immune subversion by <em>Helicobacter pylori</em>. Trends Immunol 26:199–207. <a href="https://doi.org/10.1016/j.it.2005.01.007" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.it.2005.01.007</a>
  2. Chehelgerdi M, Doosti A (2020) Effect of the cagW-based gene vaccine on the immunologic properties of BALB/c mouse: An efficient candidate for <em>Helicobacter pylori</em> DNA vaccine. J Nanobiotechnol 18:63. <a href="https://doi.org/10.1186/s12951-020-00618-1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1186/s12951-020-00618-1</a>
  3. Choi IK, Sung HJ, Lee JH et al (2012) The relationship between <em>Helicobacter pylori</em> infection and the effects of chemotherapy in patients with advanced or metastatic gastric cancer. Cancer Chemother Pharmacol 70:555–558. <a href="https://doi.org/10.1007/s00280-012-1944-5" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s00280-012-1944-5</a>
  4. Fakharian F, Asgari B, Nabavi-Rad A et al (2022) The interplay between <em>Helicobacter pylori</em> and the gut microbiota: An emerging driver influencing the immune system homeostasis and gastric carcinogenesis. Front Cell Infect Microbiol 12:953718. <a href="https://doi.org/10.3389/fcimb.2022.953718" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fcimb.2022.953718</a>
  5. Ghajari G, Nabiuni M, Amini E (2021) The association between testicular toxicity induced by Li<sub>2</sub>Co<sub>3</sub> and protective effect of Ganoderma lucidum: Alteration of Bax &amp; c-Kit genes expression. Tissue Cell 72:101552. <a href="https://doi.org/10.1016/j.tice.2021.101552" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.tice.2021.101552</a>
  6. Gupta N, Maurya S, Verma H et al (2019) Unraveling the factors and mechanism involved in persistence: Host-pathogen interactions in <em>Helicobacter pylori</em>. J Cell Biochem 120:18572–18587. <a href="https://doi.org/10.1002/jcb.29201" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1002/jcb.29201</a>
  7. He LJ, Xie D, Hu PJ et al (2015) Macrophage migration inhibitory factor as a potential prognostic factor in gastric cancer. World J Gastroenterol 21:9916–9926. <a href="https://doi.org/10.3748/wjg.v21.i34.9916" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3748/wjg.v21.i34.9916</a>
  8. Kafarski P, Talma M (2018) Recent advances in design of new urease inhibitors: A review. J Adv Res 13:101–112. <a href="https://doi.org/10.1016/j.jare.2018.01.007" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.jare.2018.01.007</a>
  9. Kang SY, Han JH, Ahn MS et al (2012) <em>Helicobacter pylori</em> infection as an independent prognostic factor for locally advanced gastric cancer patients treated with adjuvant chemotherapy after curative resection. Int J Cancer 130:948–958. <a href="https://doi.org/10.1002/ijc.26081" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1002/ijc.26081</a>
  10. Kim HJ, Kim N, Yoon H et al (2016) Comparison between resectable <em>Helicobacter pylori</em>-negative and-positive gastric cancers. Gut Liver 10:212–219. <a href="https://doi.org/10.5009/gnl14416" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.5009/gnl14416</a>
  11. Kolb JM, Ozbek U, Harpaz N (2017) Effect of <em>Helicobacter pylori</em> infection on outcomes in resected gastric and gastroesophageal junction cancer. J Gastrointest Oncol 8:583–588. <a href="https://doi.org/10.21037/jgo.2017.01.22" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.21037/jgo.2017.01.22</a>
  12. Kusters JG, Van Vliet AH, Kuipers EJ et al (2006) Pathogenesis of <em>Helicobacter pylori</em> infection. Clin Microbiol Rev 19:449–490. <a href="https://doi.org/10.1128/CMR.00054-05" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1128/CMR.00054-05</a>
  13. Larussa T, Leone I, Suraci E et al (2015) <em>Helicobacter pylori</em> and T helper cells: Mechanisms of immune escape and tolerance. J Immunol Res 2015:981328. <a href="https://doi.org/10.1155/2015/981328" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1155/2015/981328</a>
  14. Lee WJ, Lin JT, Shun CT et al (1995) Comparison between resectable gastric adenocarcinomas seropositive and seronegative for <em>Helicobacter pylori</em>. Br J Surg 82:802–805. <a href="https://doi.org/10.1002/bjs.1800820627" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1002/bjs.1800820627</a>
  15. Li G, Wang Z, Wang Z et al (2013) Gastric cancer patients with <em>Helicobacter pylori</em> infection have a poor prognosis. J Surg Oncol 108:421–426. <a href="https://doi.org/10.1002/jso.23417" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1002/jso.23417</a>
  16. Li P, Zhou L, Zhao T et al (2017) Caspase-9: Structure, mechanisms and clinical application. Oncotarget 8:23996–24008. <a href="https://doi.org/10.18632/oncotarget.15098" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.18632/oncotarget.15098</a>
  17. Maleki Kakelar H, Barzegari A, Dehghani J et al (2019) Pathogenicity of <em>Helicobacter pylori</em> in cancer development and impacts of vaccination. Gastric Cancer 22:23–36. <a href="https://doi.org/10.1007/s10120-018-0867-1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s10120-018-0867-1</a>
  18. Malfertheiner P, Megraud F, Rokkas T et al (2022) Management of <em>Helicobacter pylori</em> infection: The Maastricht VI/Florence consensus report. Gut 71:1724–1762. <a href="https://doi.org/10.1136/gutjnl-2022-327745" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1136/gutjnl-2022-327745</a>
  19. Marrelli D, Pedrazzani C, Berardi A et al (2009) Negative <em>Helicobacter pylori</em> status is associated with poor prognosis in patients with gastric cancer. Cancer 115:2071–2080. <a href="https://doi.org/10.1002/cncr.24253" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1002/cncr.24253</a>
  20. Martínez-Becerra F, Castillo-Rojas G, de León SP et al (2012) IgG subclasses against <em>Helicobacter pylori</em> isolates: An important tool for disease characterization. Scand J Immunol 76:26–32. <a href="https://doi.org/10.1111/j.1365-3083.2012.02699.x" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1111/j.1365-3083.2012.02699.x</a>
  21. Meimarakis G, Winter H, Assmann I et al (2006) <em>Helicobacter pylori</em> as a prognostic indicator after curative resection of gastric carcinoma: A prospective study. Lancet Oncol 7:211–222. <a href="https://doi.org/10.1016/S1470-2045(06)70586-1" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/S1470-2045(06)70586-1</a>
  22. Mezmale L, Coelho LG, Bordin D et al (2020) Review: Epidemiology of <em>Helicobacter pylori</em>. Helicobacter 25 Suppl 1:e12734. <a href="https://doi.org/10.1111/hel.12734" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1111/hel.12734</a>
  23. Nagaraja V, Eslick GD (2014) Evidence-based assessment of proton-pump inhibitors in <em>Helicobacter pylori</em> eradication: A systematic review. World J Gastroenterol 20:14527–14536. <a href="https://doi.org/10.3748/wjg.v20.i40.14527" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3748/wjg.v20.i40.14527</a>
  24. O’Connor A, Furuta T, Gisbert JP et al (2020) Review – treatment of <em>Helicobacter pylori</em> infection 2020. Helicobacter 25 Suppl 1:e12743. <a href="https://doi.org/10.1111/hel.12743" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1111/hel.12743</a>
  25. Park HE, Park S, Nizamutdinov D et al (2022) Antigenic determinant of <em>Helicobacter pylori</em> FlaA for developing serological diagnostic methods in children. Pathogens 11:1544. <a href="https://doi.org/10.3390/pathogens11121544" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/pathogens11121544</a>
  26. Piri-Gharaghie T, Doosti A, Mirzaei SA (2022a) Fabrication and characterization of pcDNA3. 1 (+) location within chitosan/nanoparticles complexes for enhanced gene delivery. Iran J Biotechnol 20:e3110. <a href="https://doi.org/10.30498/ijb.2022.297534.3110" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.30498/ijb.2022.297534.3110</a>
  27. Piri-Gharaghie T, Doosti A, Mirzaei SA (2022b) Identification of antigenic properties of acinetobacter baumannii proteins as novel putative vaccine candidates using reverse vaccinology approach. Appl Biochem Biotechnol 194:4892–4914. <a href="https://doi.org/10.1007/s12010-022-03995-5" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s12010-022-03995-5</a>
  28. Piri-Gharaghie T, Jegargoshe-Shirin N, Saremi-Nouri S et al (2022c) Effects of Imipenem-containing Niosome nanoparticles against high prevalence methicillin-resistant Staphylococcus Epidermidis biofilm formed. Sci Rep 12:5140. <a href="https://doi.org/10.1038/s41598-022-09195-9" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1038/s41598-022-09195-9</a>
  29. Ranjbar R, Chehelgerdi M (2018) Genotyping and antibiotic resistance properties of <em>Helicobacter pylori</em> strains isolated from human and animal gastric biopsies. Infection and drug resistance. Infect Drug Resist 11:2545–2554. <a href="https://doi.org/10.2147/IDR.S187885" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.2147/IDR.S187885</a>
  30. Scopel-Guerra A, Olivera-Severo D, Staniscuaski F et al (2017) The impact of <em>Helicobacter pylori</em> urease upon platelets and consequent contributions to inflammation. Front Microbiol 8:2447. <a href="https://doi.org/10.3389/fmicb.2017.02447" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3389/fmicb.2017.02447</a>
  31. Sharndama HC, Mba IE (2022) <em>Helicobacter pylori</em>: An up-to-date overview on the virulence and pathogenesis mechanisms. Braz J Microbiol 53:33–50. <a href="https://doi.org/10.1007/s42770-021-00675-0" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s42770-021-00675-0</a>
  32. Shatila M, Thomas AS (2022) Current and future perspectives in the diagnosis and management of <em>Helicobacter pylori</em> infection. J Clin Med 11:5086. <a href="https://doi.org/10.3390/jcm11175086" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/jcm11175086</a>
  33. Shen Z, Zhou S, Wang Y et al (2010) Higher intratumoral infiltrated Foxp3<sup>+</sup> Treg numbers and Foxp3<sup>+</sup>/CD8<sup>+</sup> ratio are associated with adverse prognosis in resectable gastric cancer. J Cancer Res Clin Oncol 136:1585–1595. <a href="https://doi.org/10.1007/s00432-010-0816-9" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1007/s00432-010-0816-9</a>
  34. Tempera PJ, Michael M, Tageldin O et al (2022) Gastric cancer due to chronic <em>H. pylori</em> infection: What we know and where we are going. Diseases 10:57. <a href="https://doi.org/10.3390/diseases10030057" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/diseases10030057</a>
  35. Tilahun M, Gedefie A, Belayhun C et al (2022) <em>Helicobacter pylori</em> pathogenicity Islands and Giardia lamblia cysteine proteases in role of coinfection and pathogenesis. Infect Drug Resist 15:21. <a href="https://doi.org/10.2147/IDR.S346705" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.2147/IDR.S346705</a>
  36. van den Engel NK, Winter H, Rüttinger D et al (2006) Characterization of immune responses in gastric cancer patients: A possible impact of <em>H. pylori</em> to polarize a tumor-specific type 1 response? Clin Immunol 120:285–296. <a href="https://doi.org/10.1016/j.clim.2006.04.566" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1016/j.clim.2006.04.566</a>
  37. Wang F, Sun G, Zou Y et al (2013) Protective role of <em>Helicobacter pylori</em> infection in prognosis of gastric cancer: Evidence from 2454 patients with gastric cancer. PLoS One 8:e62440. <a href="https://doi.org/10.1371/journal.pone.0062440" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1371/journal.pone.0062440</a>
  38. Wang SK, Zhu HF, He BS et al (2007) CagA<sup>+</sup> H pylori infection is associated with polarization of T helper cell immune responses in gastric carcinogenesis. World J Gastroenterol 13:2923. <a href="https://doi.org/10.3748/wjg.v13.i21.2923" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3748/wjg.v13.i21.2923</a>
  39. Xue LJ, Mao XB, Liu XB et al (2019) Activation of CD3<sup>+</sup> T cells by <em>Helicobacter pylori</em> DNA vaccines in potential immunotherapy of gastric carcinoma. Cancer Biol Ther 20:866–876. <a href="https://doi.org/10.1080/15384047.2019.1579957" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.1080/15384047.2019.1579957</a>
  40. Zhang J, Zhu Z, Sun Z et al (2014) Survivin gene expression increases gastric cancer cell lymphatic metastasis by upregulating vascular endothelial growth factor-C expression levels. Mol Med Rep 9:600–606. <a href="https://doi.org/10.3892/mmr.2013.1858" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3892/mmr.2013.1858</a>
  41. Zhang L, Chen X, Ren B et al (2022) <em>Helicobacter pylori</em> in the oral cavity: Current evidence and potential survival strategies. Int J Mol Sci 23:13646. <a href="https://doi.org/10.3390/ijms232113646" target="_blank" rel="noopener noreferrer" class="text-signal-blue hover:underline">https://doi.org/10.3390/ijms232113646</a>
Language: English
Submitted on: Feb 26, 2023
Accepted on: Sep 20, 2023
Published on: Feb 12, 2024
Published by: Hirszfeld Institute of Immunology and Experimental Therapy
In partnership with: Paradigm Publishing Services
Publication frequency: 1 times per year

© 2024 Mahsa Afkhamipour, Fatemeh Kaviani, Samaneh Dalali, Tohid Piri-Gharaghie, Abbas Doosti, published by Hirszfeld Institute of Immunology and Experimental Therapy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.