Formaldehyde containment efficiency with a next-generation grossing station promising safer use in anatomical pathology practice
References
- Pattavina F, Wachocka M, Tuti F, Boninti F, Santi R, Grossi R, Laurenti P. From hazard identification to risk assessment: The role of the prevention technician in the carcinogenic risk assessment for formaldehyde Front Public Health 2023:11:960921. doi: 10.3389/fpubh.2023.960921
- Directive (EU) 2019/983 of the European Parliament and of the Council [displayed 20 February 2025]. Available at
https://www.legislation.gov.uk/eudr/2019/983#:~:text=(9)%20This%20Directive%20strengthens%20the,make%20legislative%20proposals%2C%20if%20appropriate - Suvarna KS, Layton C, Bancroft JD. Bancroft's Theory and Practice of Histological Techniques. 8th ed. Elsevier 2019.
- Musiał A, Gryglewski RW, Kielczewski S, Loukas M, Wajda J. Formalin use in anatomical and histological science in the 19th and 20th centuries. Folia Med Cracov 2016;56:31–40. PMID: 28275269
- Dugheri S, Massi D, Mucci N, Berti N, Cappelli G, Arcangeli G. How improvements in monitoring and safety practices lowered airborne formaldehyde concentrations at an Italian university hospital: a summary of 20 years of experience. Arh Hig Rada Toksikol 2020;71:178–89. doi: 10.2478/aiht-2020-71-3406
- Zarbo RJ, Meier FA, Raab SS Error detection in anatomic pathology. Arch Pathol Lab Med 2025;129:1237–45. doi: 10.5858/2005-129-1237-EDIAP
- Raab SS, Grzybicki DM, Janosky JE, Zarbo RJ, Meier FA, Jensen C, Geyer SJ. Clinical impact and frequency of anatomic pathology errors in cancer diagnoses. Cancer 2025;104:2205–13. doi: 10.1002/cncr.21431
- Peck M, Moffat D, Latham B, Badrick T. Review of diagnostic error in anatomical pathology and the role and value of second opinions in error prevention. J Clin Pathol 2018;71:995–1000. doi: 10.1136/jclinpath-2018-205226
- Vollmer RT. Regarding workload and error rates in anatomic pathology. Am J Clin Pathol 2006;126(6):833. doi: 10.1309/W0K9B5F892F3R1WA
- Alaghehbandan R, Raab SS. Pathologic Mistake, 2013 [displayed 22 May 2025]. Available at
https://psnet.ahrq.gov/web-mm/pathologic-mistake - Leong AS, Braye S, Bhagwandeen B. Diagnostic “errors” in anatomical pathology: relevance to Australian laboratories. Pathology 2006;38:490–7. doi: 10.1080/00313020601032477
- Rapone M. [Errore medico: che impatto ha sulla salute pubblica, in Italian] [displayed 22 May 2025]. Available at
https://istitutomedicolegale.it/errore-medico/ - Verified Market Reports (VMR). Pathology Grossing Station Market, 2025 [displayed 20 February 2025]. Available at
https://www.verifiedmarketreports.com/product/pathology-grossing-stationmarket/ - Dugheri S, Massi D, Mucci N, Berti N, Cappelli G, Arcangeli G. Formalin safety in anatomic pathology workflow and integrated air monitoring systems for the formaldehyde occupational exposure assessment. Int J Occup Med Environ Health 2021;34:319–38. doi: 10.13075/ijomeh.1896.01649
- Dugheri S, Massi D, Mucci N, Cappelli G, Trevisani L, Arcangeli G. Formalin safety in pathology laboratory and innovative monitoring for airborne formaldehyde exposure. Sigurnost 2021;63:165–80. doi: 10.31306/s.63.2.4
- Zhang J, Wu J, Qiu Y, Song A, Li W, Li X, Liu Y. Intelligent speech technologies for transcription, disease diagnosis, and medical equipment interactive control in smart hospitals: A review. Comput Biol Med 2023;153:106517. doi: 10.1016/j.compbiomed.2022.106517
- Chow JA, Törnros ME, Waltersson M, Richard H, Kusoffsky M, Lundström CF, Kurti A. A design study investigating augmented reality and photograph annotation in a digitalized grossing workstation. J Pathol Inform 2017;8:31. doi: 10.4103/jpi.jpi_13_17
- KI-DISCUS™. KI-DISCUS systems are the world leading technology for testing microbiological safety cabinets [displayed 20 February 2025]. Available at
https://kidiscus.com/ - Nicholson G, Clark RP, de Calcina-Goff ML. Theoretical and practical comparison of the potassium iodide tracer method (KI–discus) for assessing the containment efficiency of fume cupboards with the gas tracer method described in BS 7258: 1994: Part 4. Ann Occup Hyg 1999;43:257–67. doi: 10.1016/S0003-4878(99)00025-3
- European Standard EN 12469:2000. Biotechnology - Performance criteria for microbiological safety cabinets [displayed 20 February 2025]. Available at
https://antoandoluong.com/Files/Docs/2020318155914371.pdf - Lecamwasam K, Tran H. Comparison between the potassium iodide (KI) discus test and the di-octyl phthalate (DOP) containment test for the testing of class II biological safety cabinets (BSC-II) [displayed 22 May 2025]. Available at chrome-extension://efaidnbmnnnibpcajpcglclefindmkaj/https://www.aesenvironmental.com.au/pdf/Comparison%20between%20KI%20&%20DOP_AES.pdf
- Dugheri S, Mucci N, Cappelli G, Bonari A, Garzaro G, Marrubini G, Bartolucci G, Campagna M, Arcangeli G. Monitoring of Air-Dispersed Formaldehyde and Carbonyl Compounds as Vapors and Adsorbed on Particulate Matter by Denuder-Filter Sampling and Gas Chromatographic Analysis. Int J Environ Res Public Health 2019;16(11):1969. doi: 10.3390/ijerph16111969
- European Standard EN 14175-3:2019. Fume cupboards – Part 3: Type test methods [displayed 29 May 2025]. Available at
https://cdn.standards.iteh.ai/samples/64826/1f76e12d9cc942fe989d85186f88d469/SIST-EN-14175-3-2019.pdf - National Institute for Occupational Safety and Health (NIOSH). Immediately dangerous to life or health (IDLH) values [displayed 25 May 2025]. Available at
https://www.cdc.gov/niosh/idlh/50000.html
Language: English, Croatian, Slovenian
Page range: 119 - 123
Submitted on: Feb 1, 2025
Accepted on: Jun 1, 2025
Published on: Jun 30, 2025
Published by: Institute for Medical Research and Occupational Health
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
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© 2025 Stefano Dugheri, Giovanni Cappelli, Ilaria Rapi, Niccolò Fanfani, Donato Squillaci, Antonio Baldassarre, Veronica Traversini, Simone De Sio, Nicola Mucci, published by Institute for Medical Research and Occupational Health
This work is licensed under the Creative Commons Attribution 4.0 License.