References
- Rathi BS, Kumar PS, Vo DVN. Critical review on hazardous pollutants in water environment: Occurrence, monitoring, fate, removal technologies and risk assessment. Sci Total Environ 2021;797:149134. doi: 10.1016/j.scitotenv.2021.149134
- Gavrilescu M, Demnerová K, Aamand J, Agathos S, Fava F. Emerging pollutants in the environment: present and future challenges in biomonitoring, ecological risks and bioremediation. N Biotechnol 2015;32:147–56. doi: 10.1016/j.nbt.2014.01.001
- Parmar TK, Rawtani D, Agrawal YK. Bioindicators: the natural indicator of environmental pollution. Front Life Sci 2016;9:110–8. doi: 10.1080/21553769.2016.1162753
- Burger J. Bioindicators: types, development, and use in ecological assessment and research. Environ Bioindic 2006;1:22–39. doi: 10.1080/15555270590966483
- Bjedov D, Turić N, Mikuška A, Vignjević G, Kovačić LS, Pavičić AM, Toth Jakeljić L, Velki M. The diving beetle, Cybister lateralimarginalis (De Geer, 1774), as a bioindicator for subcellular changes affected by heavy metal(loid) pollution in freshwater ecosystems. Aquatic Toxicol 2025;279:107258. doi: 10.1016/j.aquatox.2025.107258
- Bjedov D, Velki M, Toth L, Filipović Marijić V, Mikuška T, Jurinović L, Ečimović S, Turić N, Lončarić Z, Šariri S, Al Marsoomi Y, Mikuška A. Heavy metal(loid) effect on multi-biomarker responses in apex predator: Novel assays in the monitoring of white stork nestlings. Environ Pollut 2023;324:121398. doi: 10.1016/j.envpol.2023.121398
- Egwumah FA, Egwumah P, Edet D. Paramount roles of wild birds as bioindicators of contamination. Int J Avian & Wildlife Biol 2017;2:194–200. doi: 10.15406/ijawb.2017.02.00041
- Bonisoli-Alquati A, Møller AP, Rudolfsen G, Mousseau TA. Birds as bioindicators of radioactive contamination and its effects. In: Wood MD, Mothersill CE, Tsakanova G, Cresswell T, Woloschak GE, editors. Biomarkers of radiation in the environment. NATO Science for Peace and Security Series A: Chemistry and Biology. Dordrecht: Springer; 2022. p. 171–84. doi: 10.1007/978-94-024-2101-9_11
- Berglund ÅMM. Evaluating blood and excrement as bioindicators for metal accumulation in birds. Environ Pollut 2018;233:1198–206. doi: 10.1016/j.envpol.2017.10.031
- Goodale MW, Evers DC, Mierzykowski SE, Bond AL, Burgess NM, Otorowski CI, Welch LJ, Hall CS, Ellis JC, Allen RB, Diamond AW, Kress SW, Taylor RJ. Marine foraging birds as bioindicators of mercury in the Gulf of Maine. Ecohealth 2008;5:409–25. doi: 10.1007/s10393-009-0211-7
- Bjedov D, Mikuška A, Velki M, Lončarić Z, Mikuška T. The first analysis of heavy metals in the Grey Heron Ardea cinerea feathers from Croatian colonies. Larus 2020;55:7–25. doi: 10.21857/ypn4oc1kd9
- Bjedov D, Mikuška A, Gvozdić V, Glavaš P, Gradečak D, Sudarić Bogojević M. White stork pellets: Non-invasive solution to monitor anthropogenic particle pollution. Toxics 2024;12(4):236. doi: 10.3390/toxics12040236
- Bjedov D, Velki M, Lackmann C, Begović L, Mikuška T, Jurinović L, Mikuška A. Blood biomarkers in white stork (Ciconia ciconia) nestlings show different responses in several areas of Croatia. J Exp Zool A Ecol Integr Physiol 2022;337:547–58. doi: 10.1002/jez.2588
- Bjedov D, Velki M, Kovačić LS, Begović L, Lešić I, Jurinović L, Mikuška T, Sudarić Bogojević M, Ečimović S, Mikuška A. White stork (Ciconia ciconia) nestlings affected by agricultural practices? Assessment of integrated biomarker responses. Agriculture 2023;13(5):1045. doi: 10.3390/agriculture13051045
- Bjedov D, Mikuska A, Begović L, Bollinger E, Bustnes JO, Deme T, Mikuška T, Morocz A, Schulz R, Søndergaard J, Eulaers I. Effects of white-tailed eagle (Haliaeetus albicilla) nestling diet on mercury exposure dynamics in Kopački rit Nature Park, Croatia. Environ Pollut 2023;336:122377. doi: 10.1016/j.envpol.2023.122377
- Bjedov D, Bernal-Alviz J, Buelvas-Soto JA, Jurman LA, Marrugo-Negrete JL. Elevated heavy metal(loid) blood and feather concentrations in wetland birds from different trophic levels indicate exposure to environmental pollutants. Arch Environ Contam Toxicol 2024;87:127–43. doi: 10.1007/s00244-024-01085-7
- Maznikova VN, Ormerod SJ, Gómez-Serrano MÁ. Birds as bioindicators of river pollution and beyond: specific and general lessons from an apex predator. Ecol Indic 2024;158:111366. doi: 10.1016/j.ecolind.2023.111366
- Pineda-Pampliega J, Ramiro Y, Herrera-Dueñas A, Martinez-Haro M, Hernández JM, Aguirre JI, Höfle U. A multidisciplinary approach to the evaluation of the effects of foraging on landfills on white stork nestlings. Sci Total Environ 2021;775:145197. doi: 10.1016/j.scitotenv.2021.145197
- Kamiński P, Kurhalyuk N, Szady-Grad M, Tkachenko H, Kasprzak M, Jerzak J. Chemical elements in the blood of white stork Ciconia ciconia chicks in differentiated regions of Poland. Med Biol Sci 2008;22:31–7.
- Orłowski G, Polechoński R, Dobicki W, Dolata P, Bednarska M. Heavy metal concentrations in feathers of White Storks Ciconia ciconia nesting in Central Poland: methodological implications for further ecotoxicological studies. In: Tryjanowski P, Sparks TH, Jerzak L, editors. The White Stork in Poland: studies in biology, ecology and conservation. Poznań: Bogucki Wydawnictwo Naukowe; 2006. p. 237–47.
- Bialas JT, Dylewski Ł, Dylik A, Janiszewski T, Kaługa I, Królak T, Kruszyk R, Pawlukojć K, Pestka Z, Polakowski M, Zbyryt A, Tobolka M. Impact of land cover and landfills on the breeding effect and nest occupancy of the white stork in Poland. Sci Rep 2021;11(1):7279. doi: 10.1038/s41598-021-86529-z
- Hancock JA, Kushlan JA, Kahl MP. Storks, Ibises and Spoonbills of the World. London: Academic Press; 1992.
- del Hoyo J, Elliott A, Sargatal J, Christie DA. Handbook of the birds of the world. Barcelona: Lynx Edicions; 2010.
- López-García A, Martínez-Miranzo B, Aguirre JI. Influence of landfill use on nest-site selection and breeding success in white storks. J Zool 2023;321:175–87. doi: 10.1111/jzo.13105
- Gilbert NI, Correia RA, Silva JP, Pacheco C, Catry I, Atkinson PW, Gill JA, Franco AMA. Are white storks addicted to junk food? Impacts of landfill use on the movement and behaviour of resident white storks (Ciconia ciconia) from a partially migratory population. Mov Ecol 2015;4:1–13. doi: 10.1186/s40462-016-0070-0
- Tryjanowski P, Grzywaczewski G, Zbyryt A. Foraging of white stork (Ciconia ciconia) in forests – the heritage of an ancient behaviour? Pol J Ecol 2018;66:250–6. doi: 10.3161/15052249PJE2018.66.3.005
- Snow DW, Perrins CM, Gillmor R. The birds of the Western Palearctic: Non-passerines. Volume 1. Oxford: Oxford University Press; 1998.
- Bialas JT, Dylewski Ł, Tobolka M. Determination of nest occupation and breeding effect of the white stork by human-mediated landscape in Western Poland. Environ Sci Pollut Res 2020;27:4148–58. doi: 10.1007/s11356-019-06639-0
- BirdLife International. White stork [displayed 17 March 2025]. Available at:
https://datazone.birdlife.org/species/factsheet/white-stork-ciconia-ciconia - Baos R, Jovani R, Serrano D, Tella JL, Hiraldo F. Developmental exposure to a toxic spill compromises long-term reproductive performance in a wild, long-lived bird: the white stork (Ciconia ciconia). PLoS One 2012;7(4):e34716. doi: 10.1371/journal.pone.0034716
- Goutner V, Furness RW. Feathers of white stork Ciconia ciconia chicks in North-Eastern Greece, as indicators of geographical variation in mercury contamination. Toxicol Environ Chem 1998;67:379–90. doi: 10.1080/02772249809358629
- Smits JEG, Bortolotti GR, Baos R, Blas J, Hiraldo F, Xie Q. Skeletal pathology in white storks (Ciconia ciconia) associated with heavy metal contamination in southwestern Spain. Toxicol Pathol 2005;33:441–8. doi: 10.1080/01926230590953097
- The European Union for Bird Ringing. Migration Mapping Tool [displayed 17 March 2025]. Available at
https://app.bto.org/mmt/#-3.23892|50.26464|4.36|52744|1|N|0|1|0|5|Y|Y|Y - Kralj J, Barišić S, Tutiš V, Ćiković D, editors. Atlas selidbe ptica Hrvatske [Croatian bird migration atlas, in Croatian]. Zagreb: HAZU; 2013.
- Bird Migration Atlas. [displayed 17 March 2025]. Available at
https://migrationatlas.org/node/1833 - Tkachenko H, Kurhaluk N. Pollution-related changes in oxidative stress and antioxidant defense profile in the blood of white stork Ciconia ciconia chicks from different regions of Poland. Ecol Res 2013;28:869–80. doi: 10.1007/s11284-013-1070-9
- Tkachenko H, Kurhaluk N. Pollution-induced oxidative stress and biochemical parameter alterations in the blood of white stork nestlings Ciconia ciconia from regions with different degrees of contamination in Poland. J Environ Monit 2012;14:3182–91. doi: 10.1039/c2em30391d
- Tkachenko H, Kurhaluk N. Blood oxidative stress and antioxidant defense profile of White Stork Ciconia ciconia chicks reflect the degree of environmental pollution. Ecological Questions 2014;18:79–89. doi: /10.12775/ecoq-2013-0010
- Burger J. Metals in avian feathers: bioindicators of environmental pollution. Rev Environ Toxicol 1993;5:203–311.
- Furness RW. Birds as monitors of pollutants. In: Furness RW, Greenwood JJD, editors. Birds as monitors of environmental change. Dordrecht: Springer; 1993. p. 86–143.
- Janssens E, Dauwe T, Bervoets L, Eens M. Inter- and intraclutch variability in heavy metals in feathers of great tit nestlings (Parus major) along a pollution gradient. Arch Environ Contam Toxicol 2002;43:323–9. doi: 10.1007/s00244-002-0138-2
- Goutner V, Becker PH, Liordos V, Tsachalidis EP. Mercury in white stork (Ciconia ciconia) chick feathers from northeastern Mediterranean areas in relation to age, brood size, and hatching order. Arch Environ Contam Toxicol 2011;61:327–36. doi: 10.1007/s00244-010-9606-2
- Peakall D. Biomarkers of the nervous system. In: Animal biomarkers as pollution indicators. Dordrecht: Springer; 1992. p. 19–45. doi: 10.1007/978-94-011-2346-4_2
- van der Oost R, Beyer J, Vermeulen NPE. Fish bioaccumulation and biomarkers in environmental risk assessment: a review. Environ Toxicol Pharmacol 2003;13(2):57–149. doi: 10.1016/s1382-6689(02)00126-6
- Badry A, Palma L, Beja P, Ciesielski TM, Dias A, Lierhagen S, Jenssen BM, Sturaro N, Eulaers I, Jaspers VLB. Using an apex predator for large-scale monitoring of trace element contamination: Associations with environmental, anthropogenic and dietary proxies. Sci Total Environ 2019;676:746–55. doi: 10.1016/j.scitotenv.2019.04.217
- Badry A, Krone O, Jaspers VLB, Mateo R, García-Fernández A, Leivits M, Shore RF. Towards harmonisation of chemical monitoring using avian apex predators: Identification of key species for pan-European biomonitoring. Sci Total Environ 2020;731:139198. doi: 10.1016/j.scitotenv.2020.139198
- Fulton MH, Key PB. Acetylcholinesterase inhibition in estuarine fish and invertebrates as an indicator of organophosphorus insecticide exposure and effects. Environ Toxicol Chem 2001;20:37–45. doi: 10.1002/etc.5620200104
- Abbasi NA, Arukwe A, Jaspers VLB, Eulaers I, Mennillo E, Ibor OR, Frantz A, Covaci A, Malik RN. Oxidative stress responses in relationship to persistent organic pollutant levels in feathers and blood of two predatory bird species from Pakistan. Sci Total Environ 2017;580:26–33. doi: 10.1016/j.scitotenv.2016.11.197
- Halliwell B, Gutteridge JMC. Free Radicals in Biology and Medicine. 5th ed. Oxford: Oxford University Press; 2015.
- Amiard J-C, Caquet T, Lagadic L. Use of Biomarkers for Environmental Quality Assessment. London: CRC Press; 2021.
- Soreq H, Seidman S. Acetylcholinesterase - new roles for an old actor. Nat Rev Neurosci 2001;2:294–302. doi: 10.1038/35067589
- Trang A, Khandhar PB. Physiology, Acetylcholinesterase. Treasure Island (FL): StatPearls Publishing; 2022.
- Quinn DM. Acetylcholinesterase: enzyme structure, reaction dynamics, and virtual transition states. Chem Rev 1987;87:955–79. doi: 10.1021/cr00081a005
- Russell DH. Acetylcholinesterase in the hypothalamo-hypophyseal axis of the white-crowned sparrow, Zonotrichia leucophrys gambelii. Gen Comp Endocrinol 1968;11:51–63. doi: 10.1016/0016-6480(68)90106-8
- Westlake GE, Bunyan PJ, Martin AD, Stanley PI, Steed LC. Carbamate poisoning. Effects of selected carbamate pesticides on plasma enzymes and brain esterases of Japanese quail (Coturnix coturnix japonica). J Agric Food Chem 1981;29:779–85. doi: 10.1021/jf00106a022
- Hart ADM. Relationships between behavior and the inhibition of acetylcholinesterase in birds exposed to organophosphorus pesticides. Environ Toxicol Chem 1993;12:321–36. doi: 10.1002/etc.5620120215
- Tully TN, Osofsky A, Jowett PLH, Hosgood G. Acetylcholinesterase concentrations in heparinized blood of Hispaniolan Amazon parrots (Amazona ventralis). J Zoo Wildl Med 2003;34:411–3. doi: 10.1638/02-004
- Anam KK, Maitra SK. Impact of quinalphos on blood glucose and acetylcholinesterase (AChE) activity in brain and pancreas in a rose-ringed parakeet (Psittacula krameri borealis). Arch Environ Contam Toxicol 1995;29:20–3. doi: 10.1007/BF00213081
- Gard NW, Hooper MJ. Age-dependent changes in plasma and brain cholinesterase activities of eastern bluebirds and European starlings. J Wildl Dis 1993;29:1–7. doi: 10.7589/0090-3558-29.1.1
- Santos CSA, Monteiro MS, Soares AMVM, Loureiro S. Characterization of cholinesterases in plasma of three Portuguese native bird species: application to biomonitoring. PLoS One 2012;7:e33975. doi: 10.1371/journal.pone.0033975
- Bjedov D, Mikuška A, Lackmann C, Begović L, Mikuška T, Velki M. Application of non-destructive methods: biomarker assays in blood of white stork (Ciconia ciconia) nestlings. Animals 2021;11:2222. doi: 10.3390/ani11082341
- Potter P, Wadkins R. Carboxylesterases-detoxifying enzymes and targets for drug therapy. Curr Med Chem 2006;13:1045–54. doi: 10.2174/092986706776360969
- Redinbo MR, Potter PM. Mammalian carboxylesterases: from drug targets to protein therapeutics. Drug Discov Today 2005;10:313–25. doi: 10.1016/S1359-6446(05)03383-0
- Yan B. Carboxylesterases. In: Wexler P, editor. Encyclopedia of toxicology. Third Edition. Academic Press, 2014. p. 695–8.
- Bartkowiak DJ, Wilson BW. Avian plasma carboxylesterase activity as a potential biomarker of organophosphate pesticide exposure. Environ Toxicol Chem 1995;14:2149–53. doi: 10.1002/etc.5620141219
- Sogorb MA, Ganga R, Vilanova E, Soler F. Plasma phenylacetate and 1-naphthyl acetate hydrolyzing activities of wild birds as possible non-invasive biomarkers of exposure to organophosphorus and carbamate insecticides. Toxicol Lett 2007;168:278–85. doi: 10.1016/j.toxlet.2006.10.024
- Morcillo SM, Perego MC, Vizuete J, Caloni F, Cortinovis C, Fidalgo LE, López-Beceiro A, Míguez MP, Soler F, Pérez-López M. Reference intervals for B-esterases in gull, Larus michahellis (Nauman, 1840) from Northwest Spain: influence of age, gender, and tissue. Environ Sci Pollut Res 2018;25:1533–42. doi: 10.1007/s11356-017-0630-x
- Leaver MJ, George SG. A piscine glutathione S-transferase which efficiently conjugates the end-products of lipid peroxidation. Mar Environ Res 1998;46:71–4. doi: 10.1016/S0141-1136(97)00071-8
- Strange RC, Jones PW, Fryer AA. Glutathione S-transferase: genetics and role in toxicology. Toxicol Lett 2000;112–113:357–63. doi: 10.1016/s0378-4274(99)00230-1
- Csiszár J, Horváth E, Bela K, Gallé. Glutathione-related enzyme system: glutathione reductase (GR), glutathione transferases (GSTs) and glutathione peroxidases (GPXs). In: Gupta DK, Palma JM, Corpas FJ, editors. Redox state as a central regulator of plant-cell stress responses. Cham: Springer; 2016. p. 137–58.
- Hayes JD, Flanagan JU, Jowsey IR. Glutathione transferases. Annu Rev Pharmacol Toxicol 2005;45:51–88. doi: 10.1146/annurev.pharmtox.45.120403.095857
- Hayes JD, Pulford DJ. The glutathione s-transferase supergene family: Regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Part I. Crit Rev Biochem Mol Biol 1995;30:445–520. doi: 10.3109/10409239509083491
- de la Casa-Resino I, Hernández-Moreno D, Castellano A, Soler Rodríguez F, Pérez-López M. Biomarkers of oxidative status associated with metal pollution in the blood of the white stork (Ciconia ciconia) in Spain. Toxicol Environ Chem 2015;97:588–98. doi: 10.1080/02772248.2015.1051484
- Espín S, Martínez-López E, Jiménez P, María-Mojica P, García-Fernández AJ. Effects of heavy metals on biomarkers for oxidative stress in Griffon vulture (Gyps fulvus). Environ Res 2014;129:59–68. doi: 10.1016/j.envres.2013.11.008
- Espín S, Martínez-López E, León-Ortega M, Martínez JE, García-Fernández AJ. Oxidative stress biomarkers in Eurasian eagle owls (Bubo bubo) in three different scenarios of heavy metal exposure. Environ Res 2014;131:134–44. doi: 10.1016/j.envres.2014.03.015
- Oropesa AL, Gravato C, Guilhermino L, Soler F. Antioxidant defences and lipid peroxidation in wild White Storks, Ciconia ciconia, from Spain. J Ornithol 2013;154:971–6. doi: 10.1007/s10336-013-0964-1
- Amsallem-Holtzman E, Ben-Zvi Z. Drug metabolizing enzymes in the ostrich (Struthio camelus): comparison with the chicken and the rat. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol 1997;116:47–50. doi: 10.1016/s0742-8413(96)00136-3
- 78.
Kregel KC, Zhang HJ. An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations. Am J Physiol Regul Integr Comp Physiol 2007;292:R18–36. doi:
10.1152/ajpregu.00327.2006
KregelKC ZhangHJ An integrated view of oxidative stress in aging: basic mechanisms, functional effects, and pathological considerations Am J Physiol Regul Integr Comp Physiol 2007 292 R18 36 10.1152/ajpregu.00327.2006
- Martin I, Grotewiel MS. Oxidative damage and age-related functional declines. Mech Ageing Dev 2006;127:411–23. doi: 10.1016/j.mad.2006.01.008
- Vleck CM, Haussmann MF, Vleck D. Avian senescence: underlying mechanisms. J Ornithol 2007;148(Suppl 2):S611–24. doi: 10.1007/s10336-007-0186-5
- Carlberg I, Mannervik B. Glutathione reductase. Methods Enzymol 1985:113:484–90. doi: 10.1016/s0076-6879(85)13062-4
- Couto N, Wood J, Barber J. The role of glutathione reductase and related enzymes on cellular redox homoeostasis network. Free Radic Biol Med 2016:95:27–42. doi: 10.1016/j.freeradbiomed.2016.02.028
- Kamiński P, Kurhalyuk N, Kasprzak M, Jerzak L, Tkachenko H, Szady-Grad M, Klawe JJ, Koim B. The impact of element-element interactions on antioxidant enzymatic activity in the blood of white stork (Ciconia ciconia) chicks. Arch Environ Contam Toxicol 2009;56:325–37. doi: 10.1007/s00244-008-9178-6
- Kamiński P, Kurhalyuk N, Jerzak L, Kasprzak M, Tkachenko H, Klawe JJ, Szady-Grad M, Koim B, Wiśniewska E. Ecophysiological determinations of antioxidant enzymes and lipoperoxidation in the blood of White Stork Ciconia ciconia from Poland. Environ Res 2009;109:29–39. doi: 10.1016/j.envres.2008.07.013
- Upton JR, Edens FW, Ferket PR. The effects of dietary oxidized fat and selenium source on performance, glutathione peroxidase, and glutathione reductase activity in broiler chickens. J Appl Poult Res 2009;18:193–202. doi: 10.3382/JAPR.2008-00019
- Fernie KJ, Shutt JL, Mayne G, Hoffman D, Letcher RJ, Drouillard KG, Ritchie IJ. Exposure to Polybrominated Diphenyl Ethers (PBDEs): changes in thyroid, vitamin A, glutathione homeostasis, and oxidative stress in American Kestrels (Falco sparverius). Toxicol Sci 2005;88:375–83. doi: 10.1093/toxsci/kfi295
- Ezeji EU, Anyalogbu EA, Ezejiofor TN, Udensi JU. Determination of reduced glutathione and glutathione S-transferase of poultry birds exposed to permethrin insecticide. Am J Biochem 2012;2:21–4. doi: 10.5923.j.ajb.20120203.01
- Romero-Haro AA, Alonso-Alvarez C. The level of an intracellular antioxidant during development determines the adult phenotype in a bird species: a potential organizer role for glutathione. Am Nat 2015;185:390–405. doi: 10.1086/679613
- Sullivan LB, Chandel NS. Mitochondrial reactive oxygen species and cancer. Cancer Metab 2014;2(1):17. doi: 10.1186/2049-3002-2-17
- Delhaye J, Salamin N, Roulin A, Criscuolo F, Bize P, Christe P. Interspecific correlation between red blood cell mitochondrial ROS production, cardiolipin content and longevity in birds. Age (Dordr) 2016;38:433–43. doi: 10.1007/s11357-016-9940-z
- Schlezinger JJ, Keller J, Verbrugge LA, Stegeman JJ. 3,3′,4,4′-Tetrachlorobiphenyl oxidation in fish, bird and reptile species: relationship to cytochrome P450 1A inactivation and reactive oxygen production. Comp Biochem Physiol C Toxicol Pharmacol 2000;125:273–86. doi: 10.1016/s0742-8413(99)00112-7
- Babula P, Masarik M, Adam V, Eckschlager T, Stiborova M, Trnkova L, Skutkova H, Provaznik I, Hubalek J, Kizek R. Mammalian metallothioneins: properties and functions. Metallomics 2012;4:739–50. doi: 10.1039/c2mt20081c
- Scheuhammer AM, Templeton DM. Metallothionein production: similar responsiveness of avian liver and kidney to chronic cadmium administration. Toxicology 1990;60:151–9. doi: 10.1016/0300-483x(90)90169-h
- Elliott JE, Scheuhammer AM, Leighton FA, Pearce PA. Heavy metal and metallothionein concentrations in Atlantic Canadian seabirds. Arch Environ Contam Toxicol 1992;22:63–73. doi: 10.1007/BF00213303
- Marcinekova P. Metal concentrations in blood of white-tailed eagle (Haliaeetus albicilla) nestlings and potential effects on metallothionein induction. [MSc thesis]. Trondheim: Norwegian University of Science and Technology; 2019 [displayed 11 October 2022]. Available at
https://ntnuopen.ntnu.no/ntnu-xmlui/handle/11250/2621741 - Vanparys C, Dauwe T, Van Campenhout K, Bervoets L, De Coen W, Blust R, Eens M. Metallothioneins (MTs) and δ-aminolevulinic acid dehydratase (ALAd) as biomarkers of metal pollution in great tits (Parus major) along a pollution gradient. Sci Total Environ 2008;401:184–93. doi: 10.1016/j.scitotenv.2008.04.009
- Nam D-H, Anan Y, Ikemoto T, Kim E-Y, Tanabe S. Distribution of trace elements in subcellular fractions of three aquatic birds. Mar Pollut Bull 2005;51:750–6. doi: 10.1016/j.marpolbul.2005.06.002
- Barjaktarovic L, Elliott JE, Scheuhammer AM. Metal and metallothionein concentrations in Scoter (Melanitta spp.) from the Pacific Northwest of Canada, 1989–1994. Arch Environ Contam Toxicol 2002;43:486–91. doi: 10.1007/s00244-002-1273-5
- Espin S, García-Fernández A, Herzke D, Shore R, van Hattum B, Martínez-López E, Coeurdassier M, Eulaers I, Fritsch C, Gómez-Ramírez P, Jaspers VLB, Krone O, Duke G, Helander B, Mateo R, Movalli P, Sonne C, van den Brink NW. Sampling and contaminant monitoring protocol for raports, 2016. doi: 10.13140/RG.2.1.2714.8564
- Jenssen BM, Skaare JU, Ekker M, Vongraven D, Silverstone M. Blood sampling as a non-destructive method for monitoring levels and effects of organochlorines (PCB and DDT) in seals. Chemosphere 1994;28:3–10. doi: 10.1016/0045-6535(94)90196-1
- Hernández LM, González MJ, Rico MC, Fernández MA, Aranda A. Organochlorine and heavy metal residues in Falconiforme and Ciconiforme eggs (Spain). Bull Environ Contam Toxicol 1988;40:86–93. doi: 10.1007/BF01689392
- Gómez G, Baos R, Gómara B, Jiménez B, Benito V, Montoro R, Hiraldo F, González MJ. Influence of a mine tailing accident near Doñana National Park (Spain) on heavy metals and arsenic accumulation in 14 species of waterfowl (1998 to 2000). Arch Environ Contam Toxicol 2004;47:521–9. doi: 10.1007/s00244-004-0189-z
- Piedra JLV, Zienkiewicz A, Khudhur HB, Szymańczyk SE, Rumińska E. Influence of the administration of propolis and bee pollen preparation on the concentration of mercury in the muscles, kidneys and liver of white storks. Med Weter 2018;74:171–4. doi: 10.21521/mw.6082
- Kamiński P, Kurhalyuk N, Szady-Grad M. Heavy metal-induced oxidative stress and changes in physiological process of free radicals in the blood of White Stork (Ciconia ciconia) chicks in polluted areas. Pol J Environ Stud 2007;16:555–62.
- Baos R, Blas J, Bortolotti GR, Marchant TA, Hiraldo F. Adrenocortical response to stress and thyroid hormone status in free-living nestling white storks (Ciconia ciconia) exposed to heavy metal and arsenic contamination. Environ Health Perspect 2006;114:1497–501. doi: 10.1289/ehp.9099
- Baos R, Jovani R, Forero MG, Tella JL, Gómez G, Jiménez B, González MJ, Hiraldo F. Relationships between T-cell-mediated immune response and Pb, Zn, Cu, Cd, and as concentrations in blood of nestling white storks (Ciconia ciconia) and black kites (Milvus migrans) from Doñana (southwestern Spain) after the Aznalcóllar toxic spill. Environ Toxicol Chem 2006;25:1153–9. doi: 10.1897/05-395r.1
- Baos R, Jovani R, Pastor N, Tella JL, Jiménez B, Gómez G, González MJ, Hiraldo F. Evaluation of genotoxic effects of heavy metals and arsenic in wild nestling white storks (Ciconia ciconia) and black kites (Milvus migrans) from southwestern Spain after a mining accident. Environ Toxicol Chem 2006;25:2794–803. doi: 10.1897/05-570r.1
- Pastor N, López-Lázaro M, Tella JL, Baos R, Hiraldo F, Cortés F. Assessment of genotoxic damage by the comet assay in white storks (Ciconia ciconia) after the Doñana Ecological Disaster. Mutagenesis 2001;16:219–23. doi: 10.1093/mutage/16.3.219
- Maia AR, Soler-Rodriguez F, Pérez-López M. Concentration of 12 metals and metalloids in the blood of white stork (Ciconia ciconia): basal values and influence of age and gender. Arch Environ Contam Toxicol 2017;73:522–32. doi: 10.1007/s00244-017-0431-8
- Burger J, Gochfeld M. Age differences in metals in the blood of herring (Larus argentatus) and Franklin’s (Larus pipixcan) gulls. Arch Environ Contam Toxicol 1997;33:436–40. doi: 10.1007/s002449900274
- Martín B, Onrubia A, Ferrer M. Climate change and the spatiotemporal variation in survival of a long-distance migrant (White Stork, Ciconia ciconia) across western Europe. Birds 2021;2:362–80. doi: 10.3390/birds2040027
- Gade M, Comfort N, Re DB. Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms. Environ Res 2021;201:111558. doi: 10.1016/j.envres.2021.111558
- Patel CJ, Cullen MR, Ioannidis JP, Butte AJ. Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels. Int J Epidemiol 2012;41:828–43. doi: 10.1093/ije/dys003
- Espín S, Andevski J, Duke G, Eulaers I, Gómez-Ramírez P, Hallgrimsson GT, Helander B, Herzke D, Jaspers VLB, Krone O, Lourenço R, María-Mojica P, Martínez-López E, Mateo R, Movalli P, Sánchez-Virosta P, Shore RF, Sonne C, van den Brink NW, van Hattum B, Vrezec A, Wernham C, García-Fernández AJ. A schematic sampling protocol for contaminant monitoring in raptors. Ambio 2021;50:95–100. doi: 10.1007/s13280-020-01341-9
- Kulczykowska E, Kasprzak M, Kalamarz H, Kuriata M, Nietrzeba M, Jerzak L, Kamiński P. Melatonin and thyroxine response to pollution in white stork nestlings (Ciconia ciconia): aspects of rhythmicity and age. Comp Biochem Physiol C Toxicol Pharmacol 2007;146:392–7. doi: 10.1016/j.cbpc.2007.04.012
- Smits JE, Bortolotti GR, Baos R, Jovani R, Tella JL, Hoffmann WE. Disrupted bone metabolism in contaminant-exposed white storks (Ciconia ciconia) in southwestern Spain. Environ Pollut 2007;145:538–44. doi: 10.1016/j.envpol.2006.04.032
- Lashev L, Lasheva V, Daskalov Y, Chakarova V. Values of some haematological indices in white storks (Ciconia ciconia), reared in captivity. Bulg J Vet Med 2005;8:265–7.
- Pineda-Pampliega J, Herrera-Dueñas A, Mulder E, Aguirre JI, Höfle U, Verhulst S. Antioxidant supplementation slows telomere shortening in free-living white stork chicks. Proc Biol Sci 2020;287:20191917. doi: 10.1098/rspb.2019.1917
- Puerta ML, Munõz Pulido R, Huecas V, Abelenda M. Hematology and blood chemistry of chicks of white and black storks (Ciconia ciconia and Ciconia nigra). Comp Biochem Physiol A Comp Physiol 1989;94:201–4. doi: 10.1016/0300-9629(89)90535-5
- de la Casa-Resino I, Hernández-Moreno D, Castellano A, Pérez-López M, Soler F. Breeding near a landfill may influence blood metals (Cd, Pb, Hg, Fe, Zn) and metalloids (Se, As) in white stork (Ciconia ciconia) nestlings. Ecotoxicology 2014;23:1377–86. doi: 10.1007/s10646-014-1280-0
- Oropesa AL, Gravato C, Sánchez S, Soler F. Characterization of plasma cholinesterase from the white stork (Ciconia ciconia) and its in vitro inhibition by anticholinesterase pesticides. Ecotoxicol Environ Saf 2013;97:131–8. doi: 10.1016/j.ecoenv.2013.07.022
- Montesinos A, Sainz A, Pablos MV, Mazzucchelli F, Tesouro MA. Hematological and plasma biochemical reference intervals in young white storks. J Wildl Dis 1997;33:405–12. doi: 10.7589/0090-3558-33.3.405
- Höfle U, Hernández JM, Díaz-Sánchez S, Gutiérrez-Guzmán AV. White storks Ciconia ciconia and rubbish dumps, the good, the bad, and the ugly: food, pollutants, and pathogens. In: 1st International White Stork Conference; 4–6 September 2014; Zielona Góra, Poland [displayed 19 March 2025] 2014. Available at
https://digital.csic.es/handle/10261/146199 - Marinov M, Burada A, Doroşencu A, Alexe V, Teodorof L, Tigănus M, Bolboacă L-E, Tosic K, Botond Kiss J, Tudor M. Report on the accumulation of heavy metals in the feathers of some wetland birds in. the Danube delta (Romania). Rom J Biol Zool 2019;64:73–84.
- Meharg AA, Pain DJ, Ellam RM, Baos R, Olive V, Joyson A, Powell N, Green AJ, Hiraldo F. Isotopic identification of the sources of lead contamination for white storks (Ciconia ciconia) in a marshland ecosystem (Doñana, S.W. Spain). Sci Total Environ 2002;300:81–6. doi: 10.1016/s0048-9697(02)00283-8
- Pastor N, Baos R, López-Lázaro M, Jovani R, Tella JL, Hajji N, Hiraldo F, Cortés F. A 4 year follow-up analysis of genotoxic damage in birds of the Doñana area (south west Spain) in the wake of the 1998 mining waste spill. Mutagenesis 2004;19:61–5. doi: 10.1093/mutage/geg035