Figure 1

Figure 2

Figure 3

Association between anti-HBs titre threshold and the number of vaccine doses received (three or less)
| Anti-HBs <10 mIU/mL | Number of participants | Fisher’s exact test | p | |
|---|---|---|---|---|
| Number of vaccine doses | Number of participants | 30 | 7.212 | 0.015 |
| 1 | 2 | |||
| 2 | 5 | |||
| 3 | 23 | |||
| Anti-HBs ≥10 mIU/mL | ||||
| Number of vaccine doses | Number of participants | 170 | ||
| 1 | 6 | |||
| 2 | 8 | |||
| 3 | 156 | |||
Differences in sociodemographic characteristics between participants
| Variables | N (%) | Chi-squared test | p | |
|---|---|---|---|---|
| Health institution | Primary health centre | 100 (50.0) | 0.000 | 1.000 |
| Hospital | 100 (50.0) | |||
| Sex | Male | 14 (7.0) | 147.920 | 0.000 |
| Female | 186 (93.0) | |||
| Field of medicine | Surgery | 60 (30.0) | 1.030 | 0.598 |
| Internal medicine | 71 (35.5) | |||
| General medicine | 69 (34.5) | |||
| Workplace | Outpatient clinic | 102 (51.0) | 33.970 | 0.000 |
| Hospital ward | 63 (31.5) | |||
| Intensive and semi-intensive care | 35 (17.5) | |||
| Occupation | Specialist | 16 (8.0) | 248.750 | 0.000 |
| General practitioner | 7 (3.5) | |||
| College-educated nurse | 19 (9.5) | |||
| Senior nurse | 30 (15.0) | |||
| Nurse | 128 (64.0) |
Association between anti-HBs titre threshold and continuous variables
| Variables | Anti-HBs (mIU/mL) | Fisher’s exact test | p |
|---|---|---|---|
| Age | <10 | 31.334 | 0.854 |
| ≥10 | |||
| Body height | <10 | 1.552 | 0.215 |
| ≥10 | |||
| Body mass | <10 | 50.215 | 0.088 |
| ≥10 | |||
| BMI | <10 | 1.148 | 0.284 |
| ≥10 | |||
| Years of service | <10 | 0.954 | 0.330 |
| ≥10 |
Association between anti-HBs titre threshold and categorical variables
| Variables | Anti-HBs (mIU/mL) | N (%) | ANOVA test | p |
|---|---|---|---|---|
| Healthcare institution | <10 | 30 | 0.360 | 0.549 |
| ≥10 | 170 | |||
| Sex | <10 | 30 | 0.579 | 0.448 |
| ≥10 | 170 | |||
| Field of medicine | <10 | 30 | 0.179 | 0.673 |
| ≥10 | 170 | |||
| Workplace | <10 | 30 | 0.036 | 0.850 |
| ≥10 | 170 | |||
| Profession | <10 | 30 | 3.298 | 0.071 |
| ≥10 | 170 |
Association between anti-HBs titre threshold and chronic, non-infectious conditions and smoking
| Variables | Anti-HBs (mIU/mL) | Mean square | ANOVA test | p |
|---|---|---|---|---|
| Insulin dependent diabetes | <10 | 0.066 | 2.699 | 0.102 |
| ≥10 | ||||
| Insulin independent diabetes | <10 | 0.129 | 0.496 | 0.513 |
| ≥10 | ||||
| Chronic obstructive pulmonary diseases | <10 | 0.003 | 0.124 | 0.725 |
| ≥10 | ||||
| Autoimmune disease | <10 | 0.889 | 22.843 | 0.000 |
| ≥10 | ||||
| Oncological disease | <10 | 0.029 | 6.046 | 0.015 |
| ≥10 | ||||
| Liver disease | <10 | 0.020 | 2.054 | 0.153 |
| ≥10 | ||||
| Prolonged jaundice | <10 | |||
| ≥10 | 0.233 | 4.545 | 0.034 | |
| ≥10 | ||||
| Disturbance of lipid status | <10 | 0.650 | 1.312 | 0.253 |
| ≥10 | ||||
| Tobacco smoking | <10 | 6857.533 | 0.935 | 0.335 |
| ≥10 |
Differences in continuous (numerical) variables
| Variables | Mean | SD | Student’s t-test | p |
|---|---|---|---|---|
| Age | 44.52 | 10.450 | 71.330 | 0.003 |
| Body height | 168.18 | 7.046 | 175.020 | 0.000 |
| Body mass | 69.28 | 13.956 | 135.040 | 0.000 |
| BMI | 24.47 | 4.473 | 7.221 | 0.008 |
| Years of service | 4.33 | 1.939 | 44.800 | 0.000 |