Figure 1
Figure 2
Chromosome aberrations, telomere length and fragility, and oxidative stress parameters by study groups
| Exposed participants with CAs | Exposed participants without CAs | Controls | |
|---|---|---|---|
| 14 | 20 | 30 | |
| No. of dicentrics* | 4 | ||
| No. of excess acentrics* | 9 | ||
| No. of chromosome breaks* | 9 | ||
| No. of chromatid breaks* | 7 | 3 | 3 |
| No. of stable chromosome aberrations* | 2 | ||
| Average rate of breaks per cell | 0.139 | ||
| Telomere length (T/C ratio) | 40.84±1.63 | 43.54±1.08 | 41.71±1.78 |
| Rate of fragile telomeres/cell | 0.64±0.13c | 0.15±0.01c,d | 0.01±0.004 |
| PAB | 21.7±1.42 | 21.91±0.835 | 21.69±0.34 |
| LPP | 5.88±0.38a | 7.58±0.46b,c | 4.59±0.16 |
| 8-oxo dG | 100.85±7.6c | 122.41±8.15c | 45.15±1.62 |
General characteristics of study participants (N=64)
| Participants (N) | Annual TLD dose (mSv) | Male | Female | Age Mean±SD (years) | Job duration Mean±SD (years) | Smokers (N) | |
|---|---|---|---|---|---|---|---|
| Occupationally exposed to ionising radiation | 34 | 5.2±3.6 | 8 | 26 | 35.3±8.2 | 20.2±4.2 | 14 |
| Radiologists | 4 | 4.83±4.44 | 1 | 3 | 36±3.1 | 12.7±1.9 | 1 |
| Technicians | 30 | 5.25±3.46 | 7 | 23 | 43±3.7 | 24.6±2.3 | 13 |
| Controls | 30 | - | 7 | 23 | 39.5±6.8 | 21.8±5.1 | 12 |
| Total | 64 | - | 15 | 49 | 37.8±6.7 | - | 26 |