References
- Garcia-Romeu A, Kersgaard B, Addy PH. Clinical applications of hallucinogens: A review. Exp Clin Psychopharmacol 2016;24:229–68. doi: 10.1037/pha0000084
- Hwang K, Saadabadi A. Lysergic Acid Diethylamide (LSD). Treasure Island (FL): StatPearls; 2021.
- Begola MJ, Schillerstrom JE. Hallucinogens and their therapeutic use: A literature review. J Psychiatr Pract 2019;25:334–46. doi: 10.1097/PRA.0000000000000409
- Bates MLS, Trujillo KA. Use and abuse of dissociative and psychedelic drugs in adolescence. Pharmacol Biochem Behav 2021;203:173129. doi: 10.1016/j.pbb.2021.173129
- Bertron JL, Seto M, Lindsley CW. DARK classics in chemical neuroscience: Phencyclidine (PCP). ACS Chem Neurosci 2018;9:2459–74. doi: 10.1021/acschemneuro.8b00266
- Leikin JB, Krantz AJ, Zell-Kanter M, Barkin RL, Hryhorczuk DO. Clinical features and management of intoxication due to hallucinogenic drugs. Med Toxicol Adverse Drug Exp 1989;4:324–50. doi: 10.1007/BF03259916
- Xie HR, Hu L Sen, Li GY. SH-SY5Y human neuroblastoma cell line: In vitro cell model of dopaminergic neurons in Parkinson’s disease. Chin Med J 2010;123:1086–92. doi: 10.3760/cma.j.issn.0366-6999.2010.08.021
- Dolder PC, Schmid Y, Steuer AE, Kraemer T, Rentsch KM, Hammann F, Liechti ME. Pharmacokinetics and pharmacodynamics of lysergic acid diethylamide in healthy subjects. Clin Pharmacokinet 2017;56:1219–30. doi: 10.1007/s40262-017-0513-9
- Haden M, Woods B. LSD overdoses: Three case reports. J Stud Alcohol Drugs 2020;81:115–8. doi: 10.15288/jsad.2020.81.115
- Kunsman GW, Levine B, Costantino A, Smith ML. Phencyclidine blood concentrations in DRE cases. J Anal Toxicol 1997;21:498–502. doi: 10.1093/jat/21.6.498
- Walberg CB, McCarron MM, Schulze BW. Quantitation of phencyclidine in serum by enzyme immunoassay: Results in 405 patients. J Anal Toxicol 1983;7:106–10. doi: 10.1093/jat/7.2.106
- Zandona A, Katalinić M, Šinko G, Radman Kastelic A, Primožič I, Kovarik Z. Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers. Arch Toxicol 2020;94:3157–71. doi: 10.1007/s00204-020-02811-5
- Tice RR, Agurell E, Anderson D, Burlinson B, Hartmann A, Kobayashi H, Miyamae Y, Rojas E, Ryu JC, Sasaki YF. Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 2000;35:206–21. doi: 10.1002/(sici)1098-2280(2000)35:3<;206::aid-em8>3.0.co;2-j
- Kruszewski M, Sikorska K, Meczynska-Wielgosz S, Grzelak A, Sramkova M, Gabelova A, Kapka-Skrzypczak L. Comet assay in neural cells as a tool to monitor DNA damage induced by chemical or physical factors relevant to environmental and occupational exposure. Mutat Res Genet Toxicol Environ Mutagen 2019;845:402990. doi: 10.1016/j. mrgentox.2018.11.014
- Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988;175:184–91. doi: 10.1016/0014-4827(88)90265-0
- Hartmann A, Agurell E, Beevers C, Brendler-Schwaab S, Burlinson B, Clay P, Collins A, Smith A, Speit G, Thybaud V, Tice RR. Recommendations for conducting the in vivo alkaline Comet assay. Mutagenesis 2003;18:45–51. doi: 10.1093/mutage/18.1.45
- Khoschsorur GA, Winklhofer-Roob BM, Rabl H, Auer T, Peng Z, Schaur RJ. Evaluation of a sensitive HPLC method for the determination of malondialdehyde, and application of the method to different biological materials. Chromatographia 2000;52:181–4. doi: 10.1007/BF02490453
- Griffiths SM, Singh N, Jenkins GJS, Williams PM, Orbaek AW, Barron AR, Wright CJ, Doak SH. Dextran coated ultrafine superparamagnetic iron oxide nanoparticles: Compatibility with common fluorometric and colorimetric dyes. Anal Chem 2011;83:3778–85. doi: 10.1021/ac200103x
- Kamencic H, Lyon A, Paterson PG, Juurlink BHJ. Monochlorobimane fluorometric method to measure tissue glutathione. Anal Biochem 2000;286:35–7. doi: 10.1006/abio.2000.4765
- Cayman Chemical Company. Glutathione Peroxidase Assay Kit 2019 [displayed 11 November 2021]. Available at
https://www.caymanchem.com/pdfs/703102.pdf - Cayman Chemical Company. Superoxide Dismutase Assay Kit 2018:2–8 [displayed 11 November 2021]. Available at
https://www.caymanchem.com/pdfs/706002.pdf - Cayman Chemical Company. Catalase Assay Kit 2017 [displayed 11 November 2021]. Available at
https://www.caymanchem.com/pdfs/707002.pdf - Singh A, Kukreti R, Saso L, Kukreti S. Oxidative stress: A key modulator in neurodegenerative diseases. Molecules 2019;24:1583. doi: 10.3390/molecules24081583
- Traverso N, Ricciarelli R, Nitti M, Marengo B, Furfaro AL, Pronzato MA, Marinari UM, Domenicotti C. Role of glutathione in cancer progression and chemoresistance. Oxid Med Cell Longev 2013;2013:972913. doi: 10.1155/2013/972913
- Apel K, Hirt h. Reactive oxygen species: Metabolism, oxidative stress, and signal transduction. Annu Rev Plant Biol 2004;55:373–99. doi: 10.1146/annurev. arplant.55.031903.141701
- Zorova LD, Popkov VA, Plotnikov EY, Silachev DN, Pevzner IB, Jankauskas SS, Babenko VA, Zorov SD, Balakireva AV, Juhaszova M, Sollott SJ, Zorov DB. Mitochondrial membrane potential. Anal Biochem 2018;552:50–9. doi: 10.1016/j.ab.2017.07.009
- Hu Q-D, Xu LL, Gong Y, Wu GH, Wang YW, Wu SJ, Zhang Z, Mao W, Zhou YS, Li QB, Yuan JS. Lysergic acid diethylamide causes photoreceptor cell damage through inducing inflammatory response and oxidative stress. Cutan Ocul Toxicol 2018;37: 233–9. doi: 10.1080/15569527.2018.1423620
- Richter LHJ, Beck A, Flockerzi V, Maurer HH, Meyer MR. Cytotoxicity of new psychoactive substances and other drugs of abuse studied in human HepG2 cells using an adopted high content screening assay. Toxicol Lett 2019;301:79–89. doi: 10.1016/j.toxlet.2018.11.007
- Wang C, Kaufmann J, Sanchez-Ross M, Johnson K. Mechanisms of N-methyl-D-aspartate-induced apoptosis in phencyclidine-treated cultured forebrain neurons. J Pharmacol Exp Ther 2000;294:287–95. PMID: 10871324
- Azqueta A, Collins AR. The essential comet assay: A comprehensive guide to measuring DNA damage and repair. Arch Toxicol 2013;87:949–68. doi: 10.1007/s00204-013-1070-0
- Collins AR. The comet assay for DNA damage and repair: principles, applications, and limitations. Mol Biotechnol 2004;26:249–61. doi: 10.1385/MB:26:3:249
- Langie SAS, Azqueta A, Collins AR. The comet assay: Past, present, and future. Front Genet 2015;6:266. doi: 10.3389/fgene.2015.00266
- Hoag M, Trevor A, Kalir A, Castagnoli N. Phencyclidine iminium ion. NADPH-dependent metabolism, covalent binding to macromolecules, and inactivation of cytochrome(s) P-450. Drug Metab Dispos 1987;15:486–90. PMID: 2888621
- Kovacic P, Somanathan R. Mechanism of conjugated imine and iminium species, including marine alkaloids: electron transfer, reactive oxygen species, therapeutics and toxicity. Curr Bioact Compd 2010;6:46–59. doi: 10.2174/157340710790711782
- Maiti M, Das S, Sen A, Das A, Suresh Kumar G, Nandi R. Influence of DNA structures on the conversion of sanguinarine alkanolamine form to iminium form. J Biomol Struct Dyn 2002;20:455–64. doi: 10.1080/07391102.2002.10506864
- Lemone Yielding K, Sterglanz h. Lysergic acid diethylamide (LSD) binding to deoxyribonucleic acid (DNA). Proc Soc Exp Biol Med 1968;128:1096–8.
- Wagner TE. In vitro interaction of LSD with purified calf thymus DNA. Nature 1969;222:1170–2.
- Dishotsky NI, Loughman WD, Mogar RE, Lipscomb WR. LSD and genetic damage: Is LSD chromosome damaging, carcinogenic, mutagenic, or teratogenic? Science 1971;172:431–40. doi: 10.1126/science.172.3982.431
- Egozcue J, Irwin S, Maruffo CA. Chromosomal damage in LSD users. J Am Med Assoc 1968;204:214–8. doi: 10.1001/jama.1968.03140160024006
- Cohen M, Marinello M, Back N. Chromosomal damage in human leukocytes induced by lysergic acid diethylamide. Science 1967;155:1417–9. doi: 10.1126/science.155.3768.1417