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Application potential of modulation of cyclooxygenase-2 activity: a cognitive approach

Postępy Higieny i Medycyny Doświadczalnej
Volume 75 (2021): Issue 1 (January 2021)
By:
Open Access
|Dec 2021

Figures & Tables

Figure 1

Schematic diagram of omega-6 and omega-3 PUFA pathways, taking into account diet and diseases in case of imbalance between omega-6 and omega-3.
Schematic diagram of omega-6 and omega-3 PUFA pathways, taking into account diet and diseases in case of imbalance between omega-6 and omega-3.

Figure 2

Basic differences and similarities between COX isoenzymes (COX-1 and COX-2). Cellular and organ expression.
Basic differences and similarities between COX isoenzymes (COX-1 and COX-2). Cellular and organ expression.

Figure 3

Participation of COX in prostanoid biosynthesis and transformations. PGG2 (prostaglandin G2) and PGH2 (prostaglandin H2) as products of COX activity.
Participation of COX in prostanoid biosynthesis and transformations. PGG2 (prostaglandin G2) and PGH2 (prostaglandin H2) as products of COX activity.

Figure 4

Schematic diagram of pathways influencing COX/COX-2 expression in the pathomechanism of cognitive abnormalities/AD.
Schematic diagram of pathways influencing COX/COX-2 expression in the pathomechanism of cognitive abnormalities/AD.
DOI: https://doi.org/10.2478/ahem-2021-0022 | Journal eISSN: 1732-2693
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Language: English
Page range: 837 - 846
Submitted on: Dec 18, 2020
Accepted on: Jun 7, 2021
Published on: Dec 13, 2021
Published by: Hirszfeld Institute of Immunology and Experimental Therapy
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
COX-2,
COX-2 inhibitors,
cognition,
Alzheimer disease,
synaptic plasticity
Related subjects:
Life sciences,
Molecular biology,
Microbiology and virology,
Medicine,
Basic medical science,
Immunology

© 2021 Katarzyna Stachowicz, published by Hirszfeld Institute of Immunology and Experimental Therapy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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