Figure 1.
Figure 2.
Figure 3.
Figure 4.
Eye drops A composition_
| Dexamethasone | 0.05 g |
| Sodium chloride | 0.399 g |
| Carbethopendecinium bromide | 2.5 g |
| Water for injections | ad 50.0 g |
Compositions of solutions for monitoring hemolysis_
| Composition of solutions (ml) | The concentration of NaCl solutions (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1.0% | 0.9% | 0.8% | 0.7% | 0.6% | 0.5% | 0.4% | 0.3% | 0.2% | 0.1% | |
| 1% NaCl solution | 4.5 | 4.0 | 3.5 | 3.0 | 2.5 | 2.0 | 1.5 | 1.0 | 0.5 | 0 |
| Water for injections | 0 | 0.5 | 1.0 | 1.5 | 2.0 | 2.5 | 3.0 | 3.5 | 4.0 | 4.5 |
| RBC suspension | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
Measured pH values of eye drops, the density of eye drops (pycnometrically), and their surface tension (stalagmometrically) – an average of six measurements_
| Eye drops | pH | Density (g cm−3) | Surface tension (N m−1) |
|---|---|---|---|
| A | 6.626 | 1.0088 | 70.9313 |
| B (Ch) | 5.878 | 0.9953 | 70.5043 |
| C | 7.400 | 1.0059 | 35.0392 |
| D (Ch) | 5.800 | 1.0030 | 63.3394 |
| Unidexa 0.1% | 6.757 | 1.0094 | 36.9939 |
Eye drops C composition_
| Dexamethasone sodium phosphate | 0.1 g |
| Sodium chloride | 0.799 g |
| Carbethopendecinium bromide | 1.08 g |
| Water for injections | ad 100.0 g |
Eye drops B composition (with chitosan)_
| Dexamethasone | 0.05 g |
| Chitosan LMW | 0.05 g |
| Lactic acid 80% | 0.5 g |
| Water for injections | ad 50.0 g |
| Sodium hydroxide | q.s. |
Eye drops D composition (with chitosan)_
| Dexamethasone sodium phosphate | 0.1 g |
| Chitosan LMW | 0.1 g |
| Lactic acid 80% | 1.0 g |
| Water for injections | ad 100.0 g |
| Sodium hydroxide | q.s. |