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Chitosan Hydrogel Improves Bioavailability of Megosin Cover

Figures & Tables

Figure 1

Structure of megosin
Structure of megosin

Figure 2

Kinetics of megosin release from 4% chitosan gel samples
Kinetics of megosin release from 4% chitosan gel samples

Figure 3

HPLC analysis of megosin in 4% chitosan gel cross-linked with 1.4% STPP
HPLC analysis of megosin in 4% chitosan gel cross-linked with 1.4% STPP

Figure 4

Infrared spectra of chitosan (A), megosin (B), and the dried gel sample on their bases (C)
Infrared spectra of chitosan (A), megosin (B), and the dried gel sample on their bases (C)

Releasing level of megosin from chitosan hydrogels

Gel compositionRelease percentage of megosin from the gel for 7 h
Chitosan (%)Megosin (mg)STPP (%)
211.420.73 ± 2.33
221.425.88 ± 1.11
212.846.72 ± 2.58
222.832.93 ± 0.89
41059.89 ± 1.80
411.451.62 ± 1.68
412.844.91 ± 1.44
415.611.96 ± 0.69
51011.07 ± 2.13
511.46.71 ± 0.667
Language: English
Page range: 1 - 6
Submitted on: May 10, 2019
Accepted on: Jan 14, 2020
Published on: Nov 18, 2020
Published by: Comenius University in Bratislava, Faculty of Pharmacy
In partnership with: Paradigm Publishing Services
Publication frequency: 2 issues per year
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© 2020 E. M. Sultanova, M. K. Salakhutdinova, Y. I. Oshchepkova, A. M. Asrorov, M. J. Oripova, U. J. Ishimov, S. I. Salikhov, published by Comenius University in Bratislava, Faculty of Pharmacy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.