Figure 1
Structure of megosin
Table 1
Releasing level of megosin from chitosan hydrogels
| Gel composition | Release percentage of megosin from the gel for 7 h | ||
|---|---|---|---|
| Chitosan (%) | Megosin (mg) | STPP (%) | |
| 2 | 1 | 1.4 | 20.73 ± 2.33 |
| 2 | 2 | 1.4 | 25.88 ± 1.11 |
| 2 | 1 | 2.8 | 46.72 ± 2.58 |
| 2 | 2 | 2.8 | 32.93 ± 0.89 |
| 4 | 1 | 0 | 59.89 ± 1.80 |
| 4 | 1 | 1.4 | 51.62 ± 1.68 |
| 4 | 1 | 2.8 | 44.91 ± 1.44 |
| 4 | 1 | 5.6 | 11.96 ± 0.69 |
| 5 | 1 | 0 | 11.07 ± 2.13 |
| 5 | 1 | 1.4 | 6.71 ± 0.667 |
Figure 2
Kinetics of megosin release from 4% chitosan gel samples
Figure 3
HPLC analysis of megosin in 4% chitosan gel cross-linked with 1.4% STPP
Figure 4
Infrared spectra of chitosan (A), megosin (B), and the dried gel sample on their bases (C)