Have a personal or library account? Click to login

Marek Disease Virus in Serbia: Detection and Molecular Characterization (2015 – 2022)

Open Access
|Sep 2025

References

  1. Witter R, Calnek B, Buscaglia C, Gimeno I, Sc hat K: Classification of Marek’s disease viruses according to pathotype: Philosophy and methodology. Avian Pathol. 2005;34(2):75–90.
  2. OIE. Marek´s disease. In Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. In: World Organization for Animal Health (WOAH): Paris, France. 2018. p. 1–3, version adopted in May 2023.
  3. Haesendonck R, Garmyn A, Dorrestein GM, Hellebuyck T, Antonissen G, Pasmans F, Ducatelle R, Martel A: Marek’s disease virus associated ocular lymphoma in Roulroul partridges (Rollulus rouloul). Avian Pathol. 2015;44(5):347–51.
  4. Calnek BW: Pathogenesis of Marek’s Disease Virus Infection Introduction. Sequential Events Pattern of Virus Infection in Susceptible Chickens Infected with Oncogenic (Serotype-I) Virus. Pattern of Virus Infection with Nononcogenic MDV and HVT. Target Cells .. Target. 2001;
  5. Baigent SJ, Smith LP, Nair VK, Currie RJW: Vaccinal control of Marek’s disease: Current challenges, and future strategies to maximize protection. Vet Immunol Immunopathol. 2006;112(1–2):78–86.
  6. Elkhoraibi C, Blatchford RA, Pitesky ME, Mench JA: Backyard chickens in the United States: A survey of flock owners. Poult Sci. 2014;93(11):2920–31.
  7. Spalevic L, Maslic-Strizak D, Kureljusic B, Milicevic V, Radanovic O, Jezdimirovic N: Marek’s disease in the holland white crested chickens. Vet Glas. 2016;70(5–6):225–32.
  8. Song B, Zeb J, Hussain S, Aziz MU, Circella E, Casalino G, Camarda A, Yang G, Buchon N, Sparagano O: A Review on the Marek’s Disease Outbreak and Its Virulence-Related meq Genovariation in Asia between 2011 and 2021. Animals. 2022;12(5).
  9. Dunn JR, Gimeno IM: Current status of Marek’s disease in the United States and worldwide based on a questionnaire survey. Avian Dis. 2013;57(2 SUPPL. 1):483–90.
  10. Handberg KJ, Nielsen OL, Jørgensen PH: The use of serotype 1 – and serotype 3-specific polymerase chain reaction for the detection of Marek’s disease virus in chickens. Avian Pathol. 2001;30(3):243–9.
  11. Tamura K, Nei M: Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees. Mol Biol Evol. 1993;10(3):512–26.
  12. Tamura K, Stecher G, Kumar S: MEGA11: Molecular Evolutionary Genetics Analysis Version 11. Mol Biol Evol. 2021;38(7):3022–7.
  13. Felsenstein J: Confidence limits on phylogenies: an approach using the bootstrap. Evolution (N Y). 1985;39(4):783–91.
  14. ALIMS. Rispens/CVI988 [Internet]. 2024. Available from: https://www.alims.gov.rs/veterinarski-lekovi/pretrazivanje-veterinarskih-lekova/?id=472091
  15. ALIMS. RN 1250 strain [Internet]. 2024. Available from: https://www.alims.gov.rs/veterinarski-lekovi/pretrazivanje-veterinarskih-lekova/?id=489501
  16. ALIMS. vHVT013-69 strain [Internet]. 2024. Available from: https://www.alims.gov.rs/veterinarski-lekovi/pretrazivanje-veterinarskih-lekova/?id=486953
  17. Yehia N, El-Sayed HS, Omar SE, Erfan A, Amer F: Genetic evolution of Marek’s disease virus in vaccinated poultry farms. Vet World. 2021;14(5):1342–53.
  18. Trimpert J, Groenke N, Jenckel M, He S, Kunec D, Szpara ML, Spatz SJ, Osterrieder N, McMahon DP: A phylogenomic analysis of Marek’s disease virus reveals independent paths to virulence in Eurasia and North America. Evol Appl. 2017;10(10):1091–101.
  19. Massot A, Negre F, Vinci C, Dinkel T: Patterns of livestock transport in the EU and to third countries. In European Parliament, Policy Department for Structural and Cohesion Policies, Brussels.; 2021. Available from: https://www.europarl.europa.eu/thinktank/en/document/IPOL_IDA(2021)690883
  20. Krnjaić D: Poultry meat and egg production and processing sector analysis in Serbia [Internet]. Netherlands Enterprise Agency. 2022. Available from: https://zootecnicainternational.com/featured/poultry-meat-egg-production-brazil/
  21. Read AF, Baigent SJ, Powers C, Kgosana LB, Blackwell L, Smith LP, Kennedy DA, Walkden-Brown SW, Nair VK: Imperfect vaccination can enhance the transmission of highly virulent pathogens. PLoS Biol. 2015;13(7):1–18.
  22. Pejović N, Velhner M, Polaček V, Aleksić-Kovačević S, Marinković D, Knežević M: Morphological and immunohistochemical examination of tumor cells in Marek’s disease. Acta Vet Beograd. 2007;57(1):27–35.
  23. Gherman LM, Isachesku E, Zanoaga O, Braicu C, Berindan-Neagoe I: Molecular markers in canine mammary tumors. Acta Vet-Beograd 2024, 74 (2):159-182.
  24. Mete A, Gharpure R, Pitesky ME, Famini D, Sverlow K, Dunn J: Marek’s Disease in Backyard Chickens, A Study of Pathologic Findings and Viral Loads in Tumorous and Nontumorous Birds. Avian Dis. 2016;60(4):826–36.
DOI: https://doi.org/10.2478/acve-2025-0030 | Journal eISSN: 1820-7448 | Journal ISSN: 0567-8315
Language: English
Page range: 403 - 411
Submitted on: Dec 2, 2024
Accepted on: Apr 25, 2025
Published on: Sep 18, 2025
Published by: University of Belgrade, Faculty of Veterinary Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Related subjects:

© 2025 Jelena Maletić, Ljiljana Spalević, Branislav Kureljušić, Nemanja Jezdimirović, Bojan Milovanović, Jasna Kureljušić, Vesna Milićević, published by University of Belgrade, Faculty of Veterinary Medicine
This work is licensed under the Creative Commons Attribution 4.0 License.