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Marek Disease Virus in Serbia: Detection and Molecular Characterization (2015 – 2022)

Open Access
|Sep 2025

Abstract

Out of 236 samples collected from clinically suspected farms and yards, the genome of Marek’s disease virus was detected in 84 (35.59 %) samples. Results showed the significant prevalence of the virus in intensive production/commercial farms (92.86 % of total positive samples) and in the flocks of extensively raised poultry/small-scale farms (7.14 % of total positive samples). Nucleotide sequence analysis of the ICP4 gene revealed that Serbian strains were classified into A and C groups of serotypes 1, showing high similarity (>98 %) with very virulent plus (vv+MDV) pathotypes of the Hungarian strains. A retrospective analysis from 2015 to 2022 showed that the Marek disease virus continually circulates in Serbia. This study aimed to detect and molecularly characterize Marek’s disease virus strain in Serbia.

DOI: https://doi.org/10.2478/acve-2025-0030 | Journal eISSN: 1820-7448 | Journal ISSN: 0567-8315
Language: English
Page range: 403 - 411
Submitted on: Dec 2, 2024
Accepted on: Apr 25, 2025
Published on: Sep 18, 2025
Published by: University of Belgrade, Faculty of Veterinary Medicine
In partnership with: Paradigm Publishing Services
Publication frequency: 4 times per year
Related subjects:

© 2025 Jelena Maletić, Ljiljana Spalević, Branislav Kureljušić, Nemanja Jezdimirović, Bojan Milovanović, Jasna Kureljušić, Vesna Milićević, published by University of Belgrade, Faculty of Veterinary Medicine
This work is licensed under the Creative Commons Attribution 4.0 License.