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Development and evaluation of novel InhA inhibitors inspired by thiadiazole and tetrahydropyran series of inhibitors Cover

Development and evaluation of novel InhA inhibitors inspired by thiadiazole and tetrahydropyran series of inhibitors

Acta Pharmaceutica
Volume 75 (2025): Issue 2 (June 2025)
By: Martina Hrast Rambaher,  Nina Gradišek,  Rok Frlan,  Izidor Sosič,  Aljoša Bolje,  Jakob Kljun,  Martin Juhás,  Stanislav Gobec and  Stane Pajk  
Open Access
|Jul 2025

Authors

Martina Hrast Rambaher

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Nina Gradišek

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Rok Frlan

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Izidor Sosič

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Aljoša Bolje

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Jakob Kljun

University of Ljubljana, Faculty of Chemistry and Chemical Technology, Ljubljana, Slovenia

Martin Juhás

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia
Charles University, Faculty of Pharmacy in Hradec Králové, Czech Republic
University of Hradec Králové, Faculty of Science, Czech Republic

Stanislav Gobec

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Stane Pajk

stane.pajk@ffa.uni-lj.si

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia
DOI: https://doi.org/10.2478/acph-2025-0016 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 185 - 218
Accepted on: May 21, 2025
|
Published on: Jul 3, 2025
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
tuberculosis,
InhA,
direct inhibitors,
click reaction,
1,3-diol synthesis
Related subjects:
Pharmacy,
Pharmacy, other

© 2025 Martina Hrast Rambaher, Nina Gradišek, Rok Frlan, Izidor Sosič, Aljoša Bolje, Jakob Kljun, Martin Juhás, Stanislav Gobec, Stane Pajk, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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