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Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein(s) Cover

Synthesis and biochemical evaluation of new 3-amido-4-substituted monocyclic ß-lactams as inhibitors of penicillin-binding protein(s)

Acta Pharmaceutica
Volume 74 (2024): Issue 3 (September 2024)
By: Katarina Grabrijan,  Nika Strašek Benedik,  Alen Krajnc,  Krištof Bozovičar,  Damijan Knez,  Matic Proj,  Irena Zdovc,  Izidor Sosič,  Carlos Contreras-Martel,  Andréa Dessen,  Martina Hrast Rambaher and  Stanislav Gobec  
Open Access
|Sep 2024

Authors

Katarina Grabrijan

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Nika Strašek Benedik

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Alen Krajnc

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Krištof Bozovičar

The Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Damijan Knez

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Matic Proj

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Irena Zdovc

Institute of Microbiology and Parasitology, Veterinary Faculty University of Ljubljana, Ljubljana, Slovenia

Izidor Sosič

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Carlos Contreras-Martel

University Grenoble Alpes, CNRS CEA, Institut de Biologie Structurale (IBS), Bacterial Pathogenesis Group, Grenoble, France

Andréa Dessen

University Grenoble Alpes, CNRS CEA, Institut de Biologie Structurale (IBS), Bacterial Pathogenesis Group, Grenoble, France

Martina Hrast Rambaher

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia

Stanislav Gobec

stanislav.gobec@ffa.uni-lj.si

The Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia
DOI: https://doi.org/10.2478/acph-2024-0024 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 423 - 440
Accepted on: Jun 3, 2024
Published on: Sep 14, 2024
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
antibacterial agents,
monocyclic-β-lactams,
penicillin-binding proteins,
covalent inhibitors,
transpeptidase
Related subjects:
Pharmacy,
Pharmacy, other

© 2024 Katarina Grabrijan, Nika Strašek Benedik, Alen Krajnc, Krištof Bozovičar, Damijan Knez, Matic Proj, Irena Zdovc, Izidor Sosič, Carlos Contreras-Martel, Andréa Dessen, Martina Hrast Rambaher, Stanislav Gobec, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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