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Design and synthesis of amino-substituted N-arylpiperidinyl-based inhibitors of the (immuno)proteasome Cover

Design and synthesis of amino-substituted N-arylpiperidinyl-based inhibitors of the (immuno)proteasome

Acta Pharmaceutica
Volume 73 (2023): Issue 3 (September 2023)
By: Martina Gobec,  Aleš Obreza,  Marko Jukič,  Ana Baumgartner,  Nja Mihelčič,  Špela Potočnik,  Julija Virant,  Irena Mlinarič,  Raščan Stanislav and  Gobec Izidor Sosič  
Open Access
|Sep 2023

Authors

Martina Gobec

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Aleš Obreza

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Marko Jukič

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia
University of Maribor, Faculty of Chemistry and Chemical Engineering, Maribor, Slovenia

Ana Baumgartner

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Nja Mihelčič

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Špela Potočnik

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Julija Virant

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Irena Mlinarič

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Raščan Stanislav

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia

Gobec Izidor Sosič

izidor.sosic@ffa.uni-lj.si

University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia
DOI: https://doi.org/10.2478/acph-2023-0032 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 441 - 456
Accepted on: Jul 2, 2023
|
Published on: Sep 14, 2023
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year
Keywords:
proteasomes,
scaffold morphing,
optimization,
computational design,
selectivity,
inhibitors
Related subjects:
Pharmacy,
Pharmacy, other

© 2023 Martina Gobec, Aleš Obreza, Marko Jukič, Ana Baumgartner, Nja Mihelčič, Špela Potočnik, Julija Virant, Irena Mlinarič, Raščan Stanislav, Gobec Izidor Sosič, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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