Understanding endometriosis: a threat to fertility

Jeya Verschuren

doi:10.2478/acb-2024-0004

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Understanding endometriosis: a threat to fertility

Medical Journal of Cell Biology

Volume 12 (2024): Issue 1 (July 2024)

By: Jeya Verschuren

Open Access

|Jul 2024

Abstract

Endometriosis is a gynaecological disease that affects female reproductive organs by the growth of endometrium- like tissues inside and outside the pelvic cavity. This paper explored how endometriosis can lead to increased chances of infertility through a dysregulated immune system and impaired oocyte quality.

References

Sims OT, Gupta J, Missmer SA, Aninye IO. Stigma and endometriosis: a brief overview and recommendations to improve psychosocial well-being and diagnostic delay. Int J Environ Res Public Health. 2021;18(15):8210; DOI:10.3390/ijerph18158210.
Search in Google Scholar Back to article
Parasar P, Ozcan P, Terry KL. Endometriosis: epidemiology, diagnosis and clinical management. Curr Obstet Gynecol Rep. 2017;6(1):34-41; DOI:10.1007/s13669-017-0187-1.
Search in Google Scholar Back to article
University of Münster. Translational research on endometriosis. TRENDO Project [Internet]. Brussels: CORDIS European Commission; 2020 [cited 2024 Feb 20]. Available from: https://cordis.europa.eu/project/id/101008193/.
Search in Google Scholar Back to article
Yamamoto A, Johnstone EB, Bloom MS, Huddleston HG, Fujimoto VY. A higher prevalence of endometriosis among Asian women does not contribute to poorer IVF outcomes. J Assist Reprod Genet. 2017;34(6):765-74; DOI:10.1007/s10815-017-0919-1.
Search in Google Scholar Back to article
Velarde MC, Bucu MEM, Habana MAE. Endometriosis as a highly relevant yet neglected gynecologic condition in Asian women. Endocr Connect. 2023;12(11):e230169; DOI:10.1530/EC-23-0169.
Search in Google Scholar Back to article
Ramírez-Pavez TN, Martínez-Esparza M, Ruiz-Alcaraz AJ, Marín-Sánchez P, Machado-Linde F, García-Peñarrubia P. The role of peritoneal macrophages in endometriosis. Int J Mol Sci. 2021;22(19):10792; DOI:10.3390/ijms221910792.
Search in Google Scholar Back to article
Boraschi D. What Is IL-1 for? The functions of interleukin-1 across evolution. Front Immunol. 2022;13:872155; DOI:10.3389/fimmu.2022.872155.
Search in Google Scholar Back to article
Abramiuk M, Grywalska E, Małkowska P, Sierawska O, Hrynkiewicz R, Niedźwiedzka-Rystwej P. The role of the immune system in the development of endometriosis. Cells. 2022;11(13):2028; DOI:10.3390/cells11132028.
Search in Google Scholar Back to article
Arend WP, Malyak M, Guthridge CJ, Gabay C. Interleukin-1 receptor antagonist: role in biology. Annu Rev Immunol. 1998;16:27-55; DOI:10.1146/annurev.immunol.16.1.27.
Search in Google Scholar Back to article
Toczek J, Jastrzębska-Stojko Ż, Stojko R, Drosdzol-Cop A. Endometriosis: new perspective for the diagnosis of certain cytokines in women and adolescent girls, as well as the progression of disease outgrowth: a systematic review. Int J Environ Res Public Health. 2021;18(9):4726; DOI:10.3390/ijerph18094726.
Search in Google Scholar Back to article
Sharpe-Timms KL, Zimmer RL, Ricke EA, Piva M, Horowitz GM. Endometriotic haptoglobin binds to peritoneal macrophages and alters their function in women with endometriosis. Fertil Steril. 2002;78(4):810-9; DOI:10.1016/s0015-0282(02)03317-4.
Search in Google Scholar Back to article
Didziokaite G, Biliute G, Gudaite J, Kvedariene V. Oxidative stress as a potential underlying cause of minimal and mild endometriosis-related infertility. Int J Mol Sci. 2023;24(4):3809; DOI:10.3390/ijms24043809.
Search in Google Scholar Back to article
Wang Y, Zhao S. Cell types of the placenta. In: Wang Y, Zhao S, editors. Vascular biology of the placenta [Internet]. San Rafael (CA): Morgan & Claypool Life Sciences; 2010 [cited 2024 Feb 22]. Chapter 4. Available from: https://www.ncbi.nlm.nih.gov/books/NBK53245/.
Search in Google Scholar Back to article
Renaud SJ, Postovit LM, Macdonald-Goodfellow SK, McDonald GT, Caldwell JD, Graham CH. Activated macrophages inhibit human cytotrophoblast invasiveness in vitro. Biol Reprod. 2005;73(2):237-43; DOI:10.1095/biolreprod.104.038000.
Search in Google Scholar Back to article
Abbasi B, Dong Y, Rui R. Resveratrol hinders postovulatory aging by modulating oxidative stress in porcine oocytes. molecules. 2021;26(21):6346; DOI:10.3390/molecules26216346.
Search in Google Scholar Back to article
Nikbakht R, Mohammadjafari R, Rajabalipour M, Moghadam MT. Evaluation of oocyte quality in Polycystic ovary syndrome patients undergoing ART cycles. Fertil Res Pract. 2021;7(1):2; DOI:10.1186/s40738-020-00094-z.
Search in Google Scholar Back to article
Ai A, Tang Z, Liu Y, Yu S, Li B, Huang H, Wang X, Cao Y, Zhang W. Characterization and identification of human immortalized granulosa cells derived from ovarian follicular fluid. Exp Ther Med. 2019;18(3):2167-77; DOI:10.3892/etm.2019.7802.
Search in Google Scholar Back to article
Wassarman PM. Zona pellucida glycoproteins. J Biol Chem. 2008;283(36):24285-9; DOI:10.1074/jbc.R800027200.
Search in Google Scholar Back to article
Alam MH, Miyano T. Interaction between growing oocytes and granulosa cells in vitro. Reprod Med Biol. 2019;19(1):13-23; DOI:10.1002/rmb2.12292.
Search in Google Scholar Back to article
Clarke HJ. Transzonal projections: essential structures mediating intercellular communication in the mammalian ovarian follicle. Mol Reprod Dev. 2022;89(11):509-25; DOI:10.1002/mrd.23645.
Search in Google Scholar Back to article
Clarke HJ. History, origin, and function of transzonal projections: the bridges of communication between the oocyte and its environment. Anim Reprod. 2018;15(3):215-23; DOI:10.21451/1984-3143-AR2018-0061.
Search in Google Scholar Back to article
Takahashi N, Harada M, Hirota Y, Nose E, Azhary JM, Koike H, Kunitomi C, Yoshino O, Izumi G, Hirata T, Koga K, Wada-Hiraike O, Chang RJ, Shimasaki S, Fujii T, Osuga Y. Activation of endoplasmic reticulum stress in granulosa cells from patients with polycystic ovary syndrome contributes to ovarian fibrosis. Sci Rep. 2017;7(1):10824; DOI:10.1038/s41598-017-11252-7.
Search in Google Scholar Back to article
Kim P. Understanding the unfolded protein response (UPR) pathway: insights into neuropsychiatric disorders and therapeutic potentials. Biomol Ther (Seoul). 2024;32(2):183-91; DOI:10.4062/biomolther.2023.181.
Search in Google Scholar Back to article
Al-Hetty HRAK, Jabbar AD, Eremin VF, Jabbar AM, Jalil AT, Al-Dulimi AG, Gharban HAJ, Khan MUF, Saleh MM. The role of endoplasmic reticulum stress in endometriosis. Cell Stress Chaperones. 2023;28(2):145-50; DOI:10.1007/s12192-023-01323-2.
Search in Google Scholar Back to article
Fribley A, Zhang K, Kaufman RJ. Regulation of apoptosis by the unfolded protein response. Methods Mol Biol. 2009;559:191-204; DOI:10.1007/978-1-60327-017-5_14.
Search in Google Scholar Back to article
Fan W, Yuan Z, Li M, Zhang Y, Nan F. Decreased oocyte quality in patients with endometriosis is closely related to abnormal granulosa cells. Front Endocrinol (Lausanne). 2023;14:1226687; DOI:10.3389/fendo.2023.1226687.
Search in Google Scholar Back to article

Articles in this issue

DOI: https://doi.org/10.2478/acb-2024-0004 | Journal eISSN: 2544-3577

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Language: English

Page range: 30 - 33

Submitted on: Feb 26, 2024

Accepted on: Mar 29, 2024

Published on: Jul 5, 2024

Published by: Foundation for Cell Biology and Molecular Biology

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

endometriosis,

inflammatory cascade,

oocyte,

Related subjects:

© 2024 Jeya Verschuren, published by Foundation for Cell Biology and Molecular Biology
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 12 (2024): Issue 1 (July 2024)