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Best evidence for fluid resuscitation nursing in hypovolemic shock patients in emergency care based on GRADE system Cover

Best evidence for fluid resuscitation nursing in hypovolemic shock patients in emergency care based on GRADE system

Open Access
|Apr 2026

References

  1. Dormann J, Dahms K, Steinfeld E, Ansems K, Janka H, Metzendorf MI, et al. Crystalloid vs colloid solutions in hemorrhagic shock: a randomized clinical trial. J Trauma Acute Care Surg. 2016; 80:665–71.
  2. Heming N, Elatrous S, Jaber S, Dumenil AS, Cousson J, Forceville X, et al. Haemodynamic response to crystalloids or colloids in shock: an exploratory subgroup analysis of a randomised controlled trial. BMJ Open. 2017; 7:e016736. doi: 10.1136/bmjopen-2017-016736
  3. de Souza MA, da Silva Ramos FJ, Svicero BS, Nunes NF, Cunha RC, Machado FR, et al. Assessment of the components of fluid balance in patients with septic shock: a prospective observational study. Braz J Anesthesiol. 2024; 74:844483. doi: 10.1016/j. bjane.2024.844483
  4. Hasman H, Cinar O, Uzun A, Cevik E, Jay L, Comert B. A randomized clinical trial comparing the effect of rapidly infused crystalloids on acid-base status in dehydrated patients in the emergency department. Int J Med Sci. 2012; 9:59–64.
  5. Shaban EE, Elgassim M, Shaban A, Shaban A, Ahmed A, Abdelraman A, et al. Reviving the critically Ill: exploring effective fluid resuscitation approaches for diverse hypovolemic shock cases-a systematic review and meta-analysis. Bull Emerg Trauma. 2024; 12:149–61.
  6. Safiejko K, Smereka J, Pruc M, Ladny JR, Jaguszewski MJ, Filipiak KJ, et al. Efficacy and safety of hypertonic saline solutions fluid resuscitation on hypovolemic shock: a systematic review and meta-analysis of randomized controlled trials. Cardiol J. 2022; 29:966–77.
  7. Zaki HA, Bashir K, Iftikhar H, Alhatemi M, Elmoheen A. Evaluating the effectiveness of pretreatment with intravenous fluid in reducing the risk of developing contrast-Induced nephropathy: a systematic review and meta-analysis. Cureus. 2022; 14:e24825.
  8. Brignardello-Petersen R, Izcovich A, Rochwerg B, Florez ID, Hazlewood G, Alhazanni W, et al. GRADE approach to drawing conclusions from a network meta-analysis using a partially contextualised framework. BMJ. 2020; 371:m3907. doi: 10.1136/bmj.m3907
  9. Ramesh GH, Uma JC, Farhath S. Fluid resuscitation in trauma: what are the best strategies and fluids? Int J of Emerg Med. 2019; 12:38. doi: 10.1186/s12245-019-0253-8
  10. Hahn RG. Adverse effects of crystalloid and colloid fluids. Anaesthesiol Intensive Ther. 2017; 49:303–8.
  11. Bonanno FG. Management of hemorrhagic shock: physiology approach, timing and strategies. J Clin Med. 2022; 12:260. doi: 10.3390/jcm12010260
  12. Kanbay M, Copur S, Mizrak B, Ortiz A, Soler MJ. Intravenous fluid therapy in accordance with kidney injury risk: when to prescribe what volume of which solution. Clin Kidney J. 2022; 16:684–92.
  13. Shah S, Singh A, Kala S, Shetty R. Polygeline in patients with hypovolemia caused by accidental trauma: a prospective, multicentric, safety study. Int Surg J. 2018; 5:1432. doi: 10.18203/2349-2902.isj20181125
  14. Hussmann B, Lefering R, Kauther MD, Ruchholtz S, Moldzio R Lendemans S. Influence of prehospital volume replacement on outcome in polytraumatized children. Crit Care. 2012; 16:R201. doi: 10.1186/cc11809
  15. Lin L, Chu H. Meta-analysis of proportions using generalized linear mixed models. Epidemiology. 2020; 31:713–7.
  16. Moon TS, Sappenfield J. Anesthetic management and challenges in the pregnant patient. Curr Anesthesiol Rep. 2016; 6:89–94.
  17. Bishop S, Maguire S. Anaesthesia and intensive care for major burns. Contin Educ Anaesth Crit Care Pain. 2012; 12:118–22.
  18. Greenhalgh DG. Burn resuscitation: the results of the ISBI/ABA survey. Burns. 2010; 36:176–82.
  19. Poelaert J, Flamée P. Does the choice of colloids interfere with the outcome in critically ill patients? A critical appraisal. J Anaesthesiol Clin Pharmacol. 2015; 31:293–4.
  20. Khorasani EN, Mansouri F. Effect of early enteral nutrition on morbidity and mortality in children with burns. Burns J Int Soc Burn Inj. 2010; 36:1067–71.
  21. Argent LD, Verelst S, Sabbe M. Management of the pregnant trauma patient: A literature study. Open J Trauma.2020; 4(1): 038–046. DOI: https://dx.doi.org/10.17352/ojt.000031.
  22. Prowle JR, Bellomo R. Fluid administration and the kidney. Curr Opin Crit Care. 2013; 19:308–14.
  23. Zarychanski R, Abou-Setta AM, Turgeon AF, Houston BL, McIntyre L, Marshall JC, et al. Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis. JAMA. 2013; 309:678–88.
  24. Landesberg G, Gilon D, Meroz Y, Georgieva M, Levin PD, Goodman S, et al. Diastolic dysfunction and mortality in severe sepsis and septic shock. Eur Heart J. 2012; 33:895–903.
  25. Polli F, Gattinoni L. Balancing volume resuscitation and ascites management in cirrhosis. Curr Opin Anaesthesiol. 2010; 23:151–8.
  26. Nadim MK, Durand F, Kellum JA, Levitsky J, O’Leary JG, Karvellas CJ, et al. Management of the critically ill patient with cirrhosis: a multidisciplinary perspective. J Hepatol. 2016; 64:717–35.
  27. de Lange N, Schol P, Lancé M, Woiski M, Langenveld J, Rijnders R, et al. Restrictive versus massive fluid resuscitation strategy (REFILL study), influence on blood loss and hemostatic parameters in obstetric hemorrhage: study protocol for a randomized controlled trial. Trials. 2018; 19:166. doi: 10.1186/s13063-018-2512-z
  28. Lu YQ, Cai XJ, Gu LH, Wang Q, Huang WD, Bao DG. Experimental study of controlled fluid resuscitation in the treatment of severe and uncontrolled hemorrhagic shock. J Trauma. 2007; 63:798–804.
  29. Singh A, Ali S. Polygeline in hypovolemia due to traumatic injury: results of an open label study in Indian population. Int J Crit Illn Inj Sci. 2016; 6:21. doi: 10.4103/2229-5151.177362
  30. Myburgh JA, Finfer S, Bellomo R, Billot L, Cass A, Gattas D, et al. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. N Engl J Med. 2012; 367:1901–11.
  31. Lewis SR, Pritchard MW, Evans DJ, Butler AR, Alderson P, Smith AF, Roberts I. Colloids versus crystalloids for fluid resuscitation in critically ill people. Cochrane Database Syst Rev. 2018;8(8):CD000567. doi: 10.1002/14651858.CD000567.pub7.
  32. Qureshi SH, Rizvi SI, Patel NN, Murphy GJ. Meta-analysis of colloids versus crystalloids in critically ill, trauma and surgical patients. Br J Surg. 2016; 103:14–26.
  33. Lewis SR, Pritchard MW, Evans DJ, Butler AR, Alderson P, Smith AF, et al. Colloids versus crystalloids for fluid resuscitation in critically ill people. Cochrane Database Syst Rev. 2018; 8:CD000567. doi: 10.1002/14651858.CD000567.pub7
  34. Cecconi M, Hofer C, Teboul JL, Pettila V, Wilkman E, Molnar Z, et al. Fluid challenges in intensive care: the FENICE study. Intensive Care Med. 2015; 41:1529–37.
  35. Semler MW, Self WH, Wanderer JP, Ehrenfeld JM, Wang L, Byrne DW, et al. Balanced crystalloids versus saline in critically ill adults. N Engl J Med. 2018; 378:829–39.
  36. Brown RM, Wang L, Coston TD, Krishnan NI, Casey JD, Wanderer JP, et al. Balanced crystalloids versus saline in sepsis: a secondary analysis of the SMART clinical trial. Am J Respir Crit Care Med. 2019; 200:1487–95.
  37. Self WH, Semler MW, Wanderer JR Wang L, Byrne DW, Collins SR et al. Balanced crystalloids versus saline in noncritically ill adults. N Engl J Med. 2018; 378:819–28.
  38. Van Regenmortel N, Verbrugghe W, Van den Wyngaert T, Jorens PG. Impact of chloride and strong ion difference on ICU and hospital mortality in a mixed intensive care population. Ann Intensive Care. 2016; 6:91. doi: 10.1186/s13613-016-0193-x
  39. Rochwerg B, Alhazzani W, Sindi A, Heels-Ansdell D, Thabane L, Fox-Robichaud A, et al. Fluid resuscitation in sepsis: a systematic review and network meta-analysis. Ann Intern Med. 2014; 161:347–55.
  40. Dellinger RR Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013; 41:580–637.
  41. Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving sepsis campaign: 2021 international guidelines for management of sepsis and septic shock. Intensive Care Med. 2021; 47:1181–247.
  42. Wessels I, Roloff V, Rink L. Intravenous fluid therapy in adults in hospital: NICE guideline. Br J Hosp Med. 2014; 75:C78–80.
  43. Maitland K, Kiguli S, Opoka RO, Engoru C, Olupot-Olupot P, Akech SO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med. 2011; 364:2483–95.
  44. Finfer S, Liu B, Taylor C, Bellomo R, Billot L, Cook D, et al. Resuscitation fluid use in critically ill adults: an international crosssectional study in 391 intensive care units. Crit Care. 2010; 14:R185. doi: 10.1186/cc9293
  45. Malbrain MLNG, Van Regenmortel N, Saugel B, De Tavernier B, Van Gaal PJ, Joannes-Boyau O, et al. Principles of fluid management and stewardship in septic shock: it is time to consider the four D’s and the four phases of fluid therapy. Ann Intensive Care. 2018; 8:66. doi: 10.1186/s13613-018-0402-x
  46. Vincent JL, De Backer D. Circulatory shock. N Engl J Med. 2013; 369:1726–34.
  47. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016; 315:801–10.
  48. Monnet X, Marik PE, Teboul JL. Prediction of fluid responsiveness: an update. Ann Intensive Care. 2016; 6:111. doi: 10.1186/s13613-016-0216-7
  49. Bentzer P, Griesdale DE, Boyd J, MacLean K, Sirounis D, Ayas NT. Will this hemodynamically unstable patient respond to a bolus of intravenous fluids? JAMA. 2016; 316:1298–309.
  50. Lammi MR, Aiello B, Burg GT, Casey JD, Semler MW, et al. Fluid resuscitation in trauma: current clinical practice and emerging strategies. Curr Opin Crit Care. 2020; 26:662–9.
  51. Cannon JW. Hemorrhagic shock. N Engl J Med. 2018; 378:370–9.
  52. Spahn DR, Bouillon B, Cerny V, Duranteau J, Filipescu D, Hunt BJ, et al. The European guideline on management of major bleeding and coagulopathy following trauma: fifth edition. Crit Care. 2019; 23:98. doi: 10.1186/s13054-019-2347-3
  53. Holcomb JB, Tilley BC, Baraniuk S, Fox EE, Wade CE, Podbielski JM, et al. Transfusion of plasma, platelets, and red blood cells in a 1:1:1 ratio improves outcomes in severe trauma: results of the PROPPR trial. JAMA. 2015; 313:471–82.
  54. Brohi K, Gruen RL, Holcomb JB. Why are bleeding trauma patients still dying? Nat Rev Dis Primers. 2019; 5:2.
  55. Kwan I, Bunn F, Roberts I. Timing and volume of fluid administration for patients with bleeding. Cochrane Database Syst Rev. 2014; 3:CD002245. doi: 10.1002/14651858.CD002245.pub2
  56. Balogh ZJ, Reumann MK, Gruen RL, Mayer-Kuckuk P, Schuetz MA, Harris IA, et al. Advances and future directions for management of trauma patients with hemorrhagic shock. Lancet. 2016; 388:1632–48.
  57. Inaba K, Branco BC, Rhee P, Blackbourne LH, Holcomb JB, Teixeira PG, et al. Impact of prehospital blood transfusion on mortality in trauma patients. J Trauma Acute Care Surg. 2010; 69:353–62.
  58. Guyette FX, Brown JB, Zenati MS, Early-Young BJ, Adams PW, Eastridge BJ, et al. Tranexamic acid use by prehospital ground and air medical providers: a retrospective, multicenter study. Prehosp Emerg Care. 2017; 21:744–51.
  59. Green RS, Gunning WT, Gray S, Melanson SW, Brar M, et al. Nursing interventions in fluid resuscitation: a systematic review. Int Emerg Nurs. 2019; 42:34–40.
  60. Koyama T, Yamakawa K, Fujimi S. Fluid therapy in sepsis: a systematic review. Shock. 2019; 51:409–21.
  61. Silversides JA, Major E, Ferguson AJ, Mann EE, McAuley DF, Marshall JC, et al. Conservative fluid management or deresuscitation for patients with sepsis or ARDS. BMJ. 2017; 357:j2783.
  62. Acheampong A, Vincent JL. A positive fluid balance is an independent prognostic factor in patients with sepsis. Crit Care. 2015; 19:251. doi: 10.1186/s13054-015-0970-1
  63. Malbrain MLNG, Caironi P, Hahn RG, Llau JV, McDougall M, Patrão L, Ridley E, Timmins A. Multidisciplinary expert panel report on fluid stewardship: perspectives and practice. Ann Intensive Care. 2023;13(1):89. doi: 10.1186/s13613-023-01177-y
  64. Rhodes A, Evans LE, Alhazzani W, et al. Fluid resuscitation in septic shock: evolving evidence. Curr Opin Crit Care. 2017; 23:346–52.
  65. Shin CH, Long DR, McLean D, Grabitz SD, Ladha K, Timm FP, et al. Effects of intraoperative fluid management on postoperative outcomes: a hospital registry study. Ann Surg. 2018; 267:1084–92.
  66. Van der Heijden M, Verheij J, van Nieuw Amerongen GP, Groeneveld AB. Crystalloids versus colloids: differences in immunomodulatory effects. Intensive Care Med. 2009; 35:2015–24.
  67. Sakr Y, Rubatto Birri PN, Kotfis K, Nanchal R, Shah B, Kluge S, et al. Higher fluid balance increases the risk of death from sepsis: results from a large international audit. Crit Care Med. 2017; 45:386–94.
  68. O’Malley CMN, Frumento RJ, Hardy MA, Benvenisty AI, Brentjens TE, Mercer JS, et al. A randomized, double-blind comparison of lactated Ringer’s and 0.9% NaCl during renal transplantation. Anesth Analg. 2005; 100:1518–24.
  69. Young P, Bailey M, Beasley R, Henderson S, Mackle D, McArthur C, et al. Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: the SPLIT randomized clinical trial. JAMA. 2015; 314:1701–10.
  70. McIntyre LA, Rowe BH, Bagshaw SM, Chittock DR, Dhingra V, Hutchison JS, et al. A randomized trial of normothermic vs hypothermic fluid resuscitation in trauma. J Trauma. 2012; 72:23–31.
  71. Perner A, Haase N, Guttormsen AB, Tenhunen J, Klemenzson G, Åneman A, et al. Hydroxyethyl starch 130/0.42 vs Ringer’s acetate in severe sepsis. N Engl J Med. 2012; 367:124–34.
  72. Annane D, Siami S, Jaber S, Martin C, Elatrous S, Declère AD, et al. Effects of fluid resuscitation with colloids vs crystalloids on mortality in critically ill patients: the CRISTAL randomized trial. JAMA. 2013; 310:1809–17.
  73. Verheij J, van Lingen A, Beishuizen A, Christiaans HM, de Jong JR, Girbes AR, et al. Cardiac performance during acute hypervolemia in patients with septic shock. Crit Care. 2008; 12:R24.
  74. Hébert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, et al. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med. 1999; 340:409–17.
  75. Holst LB, Haase N, Wetterslev J, Wernerman J, Guttormsen AB, Karlsson S, et al. Lower vs higher hemoglobin threshold for transfusion in septic shock. N Engl J Med. 2014; 371:1381–91.
  76. Estcourt LJ, Malouf R, Hopewell S, Doree C, Trivella M, Stanworth S. Prophylactic platelet transfusions prior to surgery for people with a low platelet count. Cochrane Database Syst Rev. 2018; 9:CD012779. doi: 10.1002/14651858.CD012779.pub2
  77. Klein AA, Bailey CR, Charlton AJ, Evans E, Guckian-Fisher M, McCrossan R, et al. Association of anaesthetists guidelines: cell salvage for perioperative blood conservation. Anaesthesia. 2018; 73:1141–50.
  78. Carsetti A, Cecconi M, Rhodes A. Fluid therapy in the perioperative and critical care setting: state of the art and future directions. Crit Care. 2015; 19:259.
  79. Bampoe S, Odor PM, Dushianthan A, Bennett-Guerrero E, Cro S, Gan TJ, et al. Perioperative fluid therapy: a systematic review and meta-analysis. Anesthesiology. 2017; 126:915–32.
  80. Shrestha GS, Singh J, Acharya SP. Fluid resuscitation in burns: an update. JNMA J Nepal Med Assoc. 2015; 53:67–74.
DOI: https://doi.org/10.2478/abm-2026-0009 | Journal eISSN: 1875-855X | Journal ISSN: 1905-7415
Language: English
Page range: 72 - 84
Published on: Apr 30, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2026 Yulian Wang, Jiansheng Lin, Yanhui Lin, published by Chulalongkorn University
This work is licensed under the Creative Commons Attribution 4.0 License.