References
- 1. Papoutsakis C, Dedoussis GV. Gene-diet interactions in childhood obesity: paucity of evidence as the epidemic of childhood obesity continues to rise. Personalized Med 2007;4:133-46.
- 2. Lau FC, Bagchi M, Sen C, Roy S, Bagchi D. Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management. Curr Genomics 2008;9:239-51.
- 3. Kopelman P. Health risks associated with overweight and obesity. Obes Rev 2007;8(Suppl 1):13-7.
- 4. Newbold RR. Impact of environmental endocrine disrupting chemicals on the development of obesity. Hormones 2010;9:206-17.
- 5. Chlebowski RT. Obesity and early-stage breast cancer. J Clin Oncol 2005;23:1345-7.
- 6. Sauter ER, Scott S, Hewett J, Kliethermes B, Ruhlen RL, Basarakodu K, de la Torre R. Biomarkers associated with breast cancer are associated with obesity. Cancer Detect Prev 2008;32:149-55.
- 7. Rose DP, Vona-Davis L. Interaction between menopausal status and obesity in affecting breast cancer risk. Maturitas 2010;66:33-8.
- 8. Strom SS, Wang X, Pettaway CA, Logothetis CJ, Yamamura Y, Do KA, Babaian RJ, Troncoso P. Obesity, weight gain, and risk of biochemical failure among prostate cancer patients following prostatectomy. Clin Cancer Res 2005;11:6889-94.
- 9. Cao Y, Ma J. Body mass index, prostate cancer-specifi c mortality, and biochemical recurrence: a systematic review and meta-analysis. Cancer Prev Res 2011;4:486-501.
- 10. Kanasaki K, Koya D. Biology of obesity: lessons from animal models of obesity. J Biomed Biotechnol 2011;2011:197636. doi: 10.1155/2011/197636
- 11. Agurs-Collins T, Bouchard C. Gene-nutrition and genephysical activity interactions in the etiology of obesity. Obesity 2008;16(Suppl 3):S2-4.
- 12. Rojas J, Arraiz N, Aguirre M, Velasco M, Bermudez V. AMPK as target for intervention in childhood and adolescent o b e s i t y. J O b e s 2 0 11 ; 2 0 11 : 2 5 2 8 1 7 . d o i:10.1155/2011/252817
- 13. Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, Perusse L, Bouchard C. The human obesity gene map: the 2005 update. Obesity 2006;14:529-644.
- 14. Bouchard C. The biological predisposition to obesity: beyond the thrifty genotype scenario. Int J Obes 2007;31:1337-9.
- 15. Bray MS. Implications of gene-behavior interactions: prevention and intervention for obesity. Obesity 2008;16(Suppl 3):S72-8.
- 16. Vimaleswaran KS, Loo RJF. Progress in the genetics of common obesity and type 2 diabetes. Expert Rev Mol Med 2010;12:e7.
- 17. Chung WK, Leibel RL. Considerations regarding the genetics of obesity. Obesity 2008;16(Suppl 3):S33-9.
- 18. Martinez JA, Parra MD, Santos JL, Moreno-Aliaga MJ, Marti A, Martinez-Gonzalez MA. Genotype-dependent response to energy-restricted diets in obese subjects: towards personalized nutrition. Asia Pac J Clin Nutr 2008;117(Suppl 1):119-22.
- 19. Poehlman EE, Tremblay A, Despres JP, Fontaine E, Perusse L, Theriault G, Bouchard C. Genotype-controlled changes in body composition and fat morphology following overfeeding in twins. Am J Clin Nutr 1986;43:723-31.
- 20. Bouchard C, Tremblay A, Despres JP, Nadeau A, Lupien JP, Theriault G, Dussault J, Moorjani S, Pinault S, Fournier G. The response to long-term overfeeding in identical twins. N Engl J Med 1990;322:1477-82.
- 21. Hainer V, Stunkard AJ, Kunesova M, Parizkova J, Stich V, Allison DB. Intrapair resemblance in very low calorie dietinduced weight loss in female obese identical twins. Int J Obes Relat Metab Disord 2000;24:1051-7.
- 22. Poehlman EE, Tremblay A, Nadeau A, Dussault J, Theriault G, Bouchard C. Heredity and changes in hormones and metabolic rates with short-term training. Am J Physiol Endocrinol Metab1986;250:E711-7.
- 23. Bouchard C, Tremblay A, Despres JP, Theriault G, Nadeau A, Lupien PJ, Moorjani S, Prudhomme D, Fournier G. The response to exercise with constant energy intake in identical twins. Obes Res 1994;2:400-10.
- 24. Mammes O, Betoulle D, Aubert R, Giraud V, Tuzet S, Petiet A, Colas-Linhart N, Fumeron F. Novel polymorphisms in the 5′ region of the LEP gene: association with leptin levels and response to lowcalorie diet in human obesity. Diabetes 1998;47:487-9.
- 25. Mammes O, Betoulle D, Aubert R, Herbeth B, Siest G, Fumeron F. Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight. Ann Hum Genet 2000,64:391-4.
- 26. Mammes O, Aubert R, Betoulle D, Pean F, Herbeth B, Visvikis S, Siest G, Fumeron F. LEPR gene polymorphisms: associations with overweight, fat mass and response to diet in women. Eur J Clin Invest 2001;31:398-404.
- 27. de Luis Roman D, de la Fuente RA, Sagrado MG, Izaola O, Vicente RC. Leptin receptor Lys656Asn polymorphism is associated with decreased leptin response and weight loss secondary to a lifestyle modifi cation in obese patients. Arch Med Res 2006;37:854-9.
- 28. Lindi V, Sivenius K, Niskanen L, Laakso M, Uusitupa MI. Effect of the Pro12Ala polymorphism of the PPAR-gamma2 gene on long-term weight change in Finnish non-diabetic subjects. Diabetologia 2001;44:925-6.
- 29. Nicklas BJ, van Rossum EF, Berman DM, Ryan AS, Dennis KE, Shuldiner AR. Genetic variation in the peroxisome proliferator-activated receptor-gamma2 gene (Pro12Ala) affects metabolic responses to weight loss and subsequent weight regain. Diabetes 2001;50:2172-6.
- 30. Choquet H, Meyre D. Genomic insights into early-onset obesity. Genome Med 2010;2:36 [displayed 23 June 2010]. Available at http://genomemedicine.com/content/2/6/36
- 31. Choquet H, Meyre D. Molecular Basis of Obesity: Current Status and Future Prospects. Curr Genomics 2011;12:154-68.
- 32. Choquet H, Meyre D. Genetics of Obesity: What have we Learned? Curr Genomics 2011;12:169-79.
- 33. Su LJ, Mahabir S, Ellison GL, McGuinn LA, Reid BC. Epigenetic contributions to the relationship between cancer and dietary intake of nutrients, bioactive food components, and environmental toxicants. Front Genet 2012;2:91 [displayed 9 January 2012]. Available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3266615/pdf/fgene-02-00091.pdf
- 34. Lau C, Abbott BD, Corton JC, Cunningham ML. PPARs and Xenobiotic-Induced Adverse Effects: Relevance to Human Health. PPAR Res 2010;2010:954639. [displayed 7 June 2011]. Available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124005/?tool=pubmed
- 35. Diamanti-Kandarakis E, Bourguignon J-P, Giudice LC, Hauser R, Prins GS, Soto AM, Zoeller RT, Gore AC. Endocrine-disrupting chemicals: An endocrine society scientifi c statement. Endocrine Rev 2009;30:293-342.
- 36. Jin-Qiang C, Brown TR, Russo J. Regulation of energy metabolism pathways by estrogens and estrogenic chemicals and potential implications in obesity associated with increased exposure to endocrine disruptors. Biochim Biophys Acta 2009;1793:1128-43.
- 37. Stienstra R, Duval C, Muller M, Kersten S. PPARs, obesity, and infl ammation. PPAR Res 2007;2007:95974. [displayed 28 December 2006]. Available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783744/
- 38. Greiner T, Backhed F. Effects of the gut microbiota on obesity and glucose homeostasis. Trends Endocrinol Metab 2011;22:117-23.
- 39. Giovanni M, Gambino R, Cassader M. Obesity, diabetes, and gut microbiota: the hygiene hypothesis expanded? Diabetes Care 2010;33:2277-84.
- 40. Everard A, Lazarevic V, Derrien M, Girard M, Muccioli GG, Neyrinck AM, Possemiers S, Van Holle A, Francois P, de Vos WM, Delzenne NM, Schrenzel J, Cani PD. Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes 2011;60:2775-86.
- 41. Geurts L, Lazarevic V, Derrien M, Everard A, Van Roye M, Knauf C, Valet P, Girard M, Muccioli GG, Francois F, de Vos WM, Schrenzel J, Delzenne NM, Cani PD. Altered gut microbiota and endocannabinoid system tone in obese and diabetic leptin-resistant mice: impact on apelin regulation in adipose tissue. Front Microbiol 2011;2:149. [displayed 13 July 2011]. Available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139240/?tool=pubmed
- 42. McAllister EJ, Dhurandhar NV, Keith SW, Aronne LJ, Barger J, Baskin M, Benca RM, Biggio J, Boggiano MM, Eisenmann JC, Elobeid M, Fontaine KR, Gluckman P, Hanlon EC, Katzmarzyk P, Pietrobelli A, Redden DT, Ruden DM, Wang C, Waterland RA, Wright SM, Allison DB. Ten putative contributors to the obesity epidemic. Crit Rev Food Sci Nutr 2009;49:868-913.
- 43. Steger DJ, Lazar MA. Adipogenic hotspots: where the action is. EMBO J 2011;30:1418-9.
- 44. Ahima RS. Digging deeper into obesity J Clin Invest 2011;121:2076-9.
- 45. Grun F, Blumberg B. Environmental obesogens organotins and endocrine disruption via nuclear receptor signaling. Endocrinology 2006;147(Suppl 6):S50-5.
- 46. Casals-Casas C, Feige JN, Desvergne B. Interference of pollutants with PPARs: endocrine disruption meets metabolism. Int J Obes 2008;32(Suppl 6):S53-61.
- 47. Grun F, Blumberg B. Minireview: the case for obesogens. Mol Endocrinol 2009;23:1127-34.
- 48. Grun F, Blumberg B. Endocrine disrupters as obesogens. Mol Cell Endocrinol 2009;304:19-29.
- 49. Kirchne S, Kieu T, Chow C, Casey S, Blumberg B. Prenatal exposure to the environmental obesogen tributyltin predisposes multipotent stem cells to become adipocytes. Mol Endocrinol 2010;24:526-39.
- 50. Tsuda T, Inoue T, Kojima M, Aoki S. Daily intakes of tributyltin and triphenyltin compounds from meals. J AOAC Int 1995;78:941-3.
- 51. Guerin T, Sirot V, Volatier JL, Leblanc JC. Organotin levels in seafood and its implications for health risk in high-seafood consumers. Sci Total Environ 2007;388:66-77.
- 52. Ohno H, Suzuki M, Nakashima S, Aoyama T, Mitani K. [Determination of organotin compounds in plastic products by GC/MS after ethyl derivatization with sodium tetraethylborate, in Japanese]. Shokuhin Eiseigaku Zasshi 2002;43:208-14.
- 53. Grun F, Watanabe H, Zamanian Z, Maeda L, Arima K, Cubacha R, Gardiner DM, Kanno J, Iguchi T, Blumberg B. Endocrinedisrupting organotin compounds are potent inducers of adipogenesis in vertebrates. Mol Endocrinol 2006;20:2141-55.
- 54. Decherf S, Demeneix BA. The obesogen hypothesis: a shift of focus from the periphery to the hypothalamus. J Toxicol Environ Health B Crit Rev 2011;14:423-48.
- 55. Wetherill YB, Akingbemi BT, Kanno J, McLachlan JA, Nadal A, Sonnenschein C, Watson CS, Zoeller RT, Belcher SM. In vitro molecular mechanisms of bisphenol A action. Reprod Toxicol 2007;24:178-98.
- 56. Richter CA, Birnbaum LS, Farabollini F, Newbold RR, Rubin BS, Talsness CE, Vandenbergh JG, Walser-Kuntz DR, vom Saal FS. In vivo effects of bisphenol A in laboratory rodent studies. Reprod Toxicol 2007;24:199-224.
- 57. Somm E, Schwitzgebel VM, Toulotte A, Cederroth CR, Combescure C, Nef S, Aubert ML, Huppi PS. Perinatal exposure to bisphenol a alters early adipogenesis in the rat. Environ Health Perspect 2009;117:1549-55.
- 58. Rubin BS, Murray MK, Damassa DA, King JC, Soto AM. Perinatal exposure to low doses of bisphenol A affects body weight, patterns of estrous cyclicity, and plasma LH levels. Environ Health Perspect 2001;109:675-80.
- 59. Nikaido Y, Danbara N, Tsujita-Kyutoku M, Yuri T, Uehara N, Tsubura A. Effects of prepubertal exposure to xenoestrogen on development of estrogen target organs in female CD-1 mice. In Vivo 2005;19:487-94.
- 60. Honma S, Suzuki A, Buchanan DL, Katsu Y, Watanabe H, Iguchi T. Low dose effect of in utero exposure to bisphenol A and diethylstilbestrol on female mouse reproduction. Reprod Toxicol 2002;16:117-22.
- 61. Goldberg RB. The new clinical trials with thiazolidinediones - DREAM, ADOPT, and CHICAGO: promises fulfi lled? Curr Opin Lipidol 2007;18:435-42.
- 62. Tiwari HK, Patki A, Lieberman J, Stroup TS, Allison DB, Leibel RL, Chung WK. Association of allelic variation in genes mediating aspects of energy homeostasis with weight gain during administration of antipsychotic drugs (CATIE Study). Front Genet 2011;2:56 [displayed 1 September 2011]. Available at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202977/?tool=pubmed
- 63. Graham JD, Ouellet-Hellstrom R, MaCurdy TE, Farzana Ali F, Christopher Sholley C, Worrall C, Kelman JA. Risk of acute myocardial infarction, stroke, heart failure, and death in elderly Medicare patients treated with rosiglitazone or pioglitazone. JAMA 2010;304:411-8.
- 64. Agurs-Collins T, Khoury MJ, Simon-Morton D, Olster DH. Public health genomics: translating obesity genomics research into population health benefits. Obesity 2008;16(Suppl 3):S85-94.
- 65. Caulfi eld T, Shelley J, Alfonso V, Bubela T. Nutrigenomics and the promise of prevention: representations and realities. Health Law J 2008;1:41-66.
- 66. Lairon D, Defoort C, Martin JC, Amiot-Carlin MJ, Gastaldi M, Planells R. Nutrigenetics: links between genetic background and response to Mediterranean-type diets. Public Health Nutr 2009;12:1601-6.
- 67. Miggiano GA, De Sanctis R. [Nutritional genomics: toward a personalized diet, in Italian]. Clin Ter 2006;157:355-61.
- 68. Nutritional outlook. The future of Nutrigenomics [displayed 16 October 2006]. Available at http://www.nutritionaloutlook.com/article/future-nutrigenomics
- 69. Bašić M, Zrnec D, Butorac A, Landeka Jurčević I, Đikić D, Bačun-Družina V. Što je nutrigenomika? [What is nutrigenomics? in Croatian]. Croat J Food Technol Biotechnol Nutr 2011;6:37-44.
- 70. Arkadianos I, Valdes AM, Marinos E, Florou A, Gill RD, Grimaldi KA. Improved weight management using genetic information to personalize a calorie controlled diet. Nutr J 2007;6:29 [displayed 18 October 2007]. Available at http:// www.ncbi.nlm.nih.gov/pmc/articles/PMC2151062/
- 71. Gorduza EV, Indrei LL, Gorduza VM. Nutrigenomics in postgenomic era. Rev Med Chir Soc Med Nat Iasi 2008;112:152-64.
- 72. Kim EJ, Kim E, Kwon EY, Jang HS, Hur CG, Choi MS. Network analysis of hepatic genes responded to high-fat diet in C57BL/6J mice: nutrigenomics data mining from recent research fi ndings. J Med Food 2010;13:743-56.
- 73. Levesque L, Ozdemir V, Godard B. Socio-ethical analysis of equity in access to nutrigenomics interventions for obesity prevention: a focus group study. OMICS 2008;12:273-8.
- 74. Steemburgo T, Azevedo MJ, Martinez JA. [Gene-nutrient interaction and its association with obesity and diabetes mellitus, in Portuguese]. Arq Bras Endocrinol Metabol 2009;53:497-508.
- 75. Tapsell LC, Probst YC. Nutrition in the prevention of chronic diseases. World Rev Nutr Diet 2008;98:94-105.
- 76. Ordovas JM. Genotype-phenotype associations: modulation by diet and obesity. Obesity 2008;16(Suppl 3):S40-6.
- 77. Sotos-Prieto M, Guillen M, Guillem-Saiz P, Portoles O, Corella D. The rs1466113 polymorphism in the somatostatin receptor 2 gene is associated with obesity and food intake in a Mediterranean population. Ann Nutr Metab 2010;57:124-31.
- 78. Ntalla I, Dedoussis G, Yannakoulia M, Smart MC, Louizou E, Sakka SD, Papoutsakis C, Talmud PJ. ADIPOQ gene polymorphism rs1501299 interacts with fi bre intake to affect adiponectin concentration in children: the GENe-Diet Attica Investigation on childhood obesity. Eur J Nutr 2009;48:493-7.
- 79. Varma V, Wise C, Kaput J. Carbohydrate metabolic pathway genes associated with quantitative trait loci (QTL) for obesity and type 2 diabetes: identifi cation by data mining. Biotechnol J 2010;5:942-9.
- 80. Stryjecki C, Mutch DM. Fatty acid-gene interactions, adipokines and obesity. Eur J Clin Nutr 2011;65:285-97.
- 81. Hotamisligil GS. Infl ammation and metabolic disorders. Nature 2006;444:860-7.
- 82. Ronti T, Lupattelli G, Mannarino E. The endocrine function of adipose tissue: an update. Clin Endocrinol 2006;64:355-65.
- 83. Trayhurn P, Beattie JH. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc 2001;60:329-39.
- 84. Wang P, Mariman E, Renes J, Keijer J. The secretory function of adipocytes in the physiology of white adipose tissue. J Cell Physiol 2008;216:3-13.
- 85. Pischon T, Girman CJ, Hotamisligil GS, Rifai N, Hu FB, Rimm EB. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 2004;291:1730-7.
- 86. Schulze MB, Rimm EB, Shai I, Rifai N, Hu FB. Relationship between adiponectin and glycemic control, blood lipids, and infl ammatory markers in men with type 2 diabetes. Diabetes Care 2004;27:1680-7.
- 87. Hu FB, Meigs JB, Li TY, Rifai N, Manson JE. Infl ammatory markers and risk of developing type 2 diabetes in women. Diabetes 2004;53:693-700.
- 88. Danesh J, Wheeler JG, Hirschfi eld GM, Eda S, Eiriksdottir G, Rumley A, Lowe GD, Pepys MB, Gudnason V. C-reactive protein and other circulating markers of infl ammation in the prediction of coronary heart disease. N Engl J Med 2004;350:1387-97.
- 89. Puglisi MJ, Fernandez ML. Modulation of C-reactive protein, tumor necrosis factor-α, and adiponectin by diet, exercise, and weight loss. J Nutr 2008;138:2293-6.
- 90. Trichopoulou A, Bamia C, Trichopoulos D. Anatomy of health effects of Mediterranean diet: Greek EPIC prospective cohort study. B M J 2009;338:b2337. [displayed 23 June 2009]. Available at http://www.ncbi.nlm. nih.gov/pmc/articles/PMC3272659/?tool=pubmed
- 91. Esposito K, Marfella R, Ciotola M, Di Palo C, Giugliano F, Giugliano G, D’Armiento M, D’Andrea F, Giugliano D. Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular infl ammation in the metabolic syndrome: a randomized trial. JAMA 2004;292:1440-6.
- 92. Bakker GC, van Erk MJ, Pellis L, Wopereis S, Rubingh CM, Cnubben NHP. An antiinfl ammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach. Am J Clin Nutr 2010;91:1044-59.
- 93. Goyenechea E, Parra D, Crujeiras AB, Abete I, Martinez JA. A nutrigenomic infl ammation-related PBMC-based approach to predict the weight-loss regain in obese subjects. Ann Nutr Metab 2009;54:43-51.
- 94. Caimari A, Oliver P, Keijer J, Palou A. Peripheral blood mononuclear cells as a model to study the response of energy homeostasis-related genes to acute changes in feeding conditions. OMICS 2010;14:129-41.
- 95. Goyenechea E, Crujeiras AB, Abete I, Martinez JA. Expression of two infl ammation-related genes (RIPK3 and RNF216) in mononuclear cells is associated with weight-loss regain in obese subjects. J Nutrigenet Nutrigenomics 2009;2:78-84.
- 96. Rimbach G, Minihane AM. Nutrigenetics and personalised nutrition: how far have we progressed and are we likely to get there. Proc Nutr Soc 2009;68:162-72.
- 97. Stewart-Knox BJ, Bunting BP, Gilpin S, Parr HJ, Pinhao S, Strain JJ, de Almeida MD, Gibney M. Attitudes toward genetic testing and personalised nutrition in a representative sample of European consumers. Br J Nutr 2009;101:982-9.
- 98. Alfredo Martinez J, Martinez-Hernandez A, Enriquez L, Moreno-Aliaga MJ, Moreno-Moreno MJ, Marti A. Genetics of obesity. Public Health Nutr 2007;10:1138-44.