References
- Anonimous: The renaissance of rational polytherapy: the new generation of antiepileptic medications. Neurology, 1995, 45: 35–38.
- Barcs G., Walker E.B., Elger C.E., Scaramelli A., Stefan H., Sturm T. et al.: Oxcarbazepine placebo-controlled, dose-ranging trial in refractory partial epilepsy. Epilepsia, 2000, 4: 1597–1607.
- Barker-Haliski M., Sills G.J., White H.S.: What are the arguments for and against rational therapy for epilepsy? Adv. Exp. Med. Biol., 2014, 813: 295–308. Available at: https://link.springer.com/chapter/10.1007%2F978-94-017-8914-1_24.
- Baulac M., Brodie M.J., Patten A., Segieth J., Giorgi L.: Efficacy and tolerability of zonisamide versus controlled-release carbamazepine for newly diagnosed partial epilepsy: a phase 3, randomised, double-blind, non-inferiority trial. Lancet Neurol., 2012, 11: 579–588.
- Beghi E., Tonini C., Ben-Menachem E., Chadwick D.W., Nikanorova M.: Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial. Epilepsy Res., 2003, 57: 1–13.
- Ben-Menachem E.: Medical management of refractory epilepsy-practical treatment with novel antiepileptic drugs. Epilepsia, 2014, 55: 3–8.
- Besag F.M., Berry D.J., Pool F., Newberg J.E., Subel B.: Carbamazepine toxicity with lamotrigine: pharmacokinetic or pharmacodynamic interaction? Epilepsia, 1998, 39: 183–187.
- Borowicz K.K., Swiader M., Luszczki J., Czuczwar S. J.: Effect of gabapentin on the anticonvulsant activity of antiepileptic drugs against electroconvulsions in mice: an isobolographic analysis. Epilepsia, 2002, 43: 956–963. Available at: http://onlinelibrary.wiley.com/store/10.1046/j.1528-1157.2002.34301.x/asset/j.1528-1157.2002.34301.x.pdf?v=1&;t=jeirjnx7&s=1bbfc6383dd021f64099062233d819038b8eecbd.
- Brigo F., Ausserer H., Tezzon F., Nardone R.: When one plus one makes three: the quest for rational antiepileptic polytherapy with supraadditive anticonvulsant efficacy. Epilepsy Behav., 2013, 27: 439–442.
- Brodie M.J., French J.A., McDonald S.A., Lee W.-J., Adams B., Scott A., Nohria V., DeRossett S.: Adjunctive use of ezogabine/ retigabine with either traditional sodium channel blocking antiepileptic drugs (AEDs) or AEDs with other mechanisms of action: Evaluation of efficacy and tolerability. Epilepsy Res., 2014, 108: 989–994. Available at: https://www.sciencedirect.com/science/article/pii/S0920121114000825?via%3Dihub.
- Brodie M.J.: Road to refractory epilepsy: the Glasgow story. Epilepsia, 2013, 54: 5–8.
- Brodie M.J.: Pharmacological treatment of drug-resistant epilepsy in adults: a practical guide. Curr. Neurol. Neurosci. Rep., 2016, 16: 82. doi: 10.1007/s11910-016-0678-x
- Brodie M.J., Munford J.P.: Double-blind substitution of vigabatrin and valproate in carbamazepine-resistant partial epilepsy. 012 Study group. Epilepsy Res., 1999, 34: 199–205.
- Brodie M.J., Sills G.J.: Combining antiepileptic drugs-rational polytherapy? Seizure, 2011, 20: 369–375.
- Brodie M.J., Yuen A.W.: Lamotrigine substitution study: evidence for synergism with sodium valproate? 105 Study Group. Epilepsy Res., 1997, 26: 423–432.
- Brodie M.J., Bamagous G.K.P.: Improved outcomes in newly diagnosed epilepsy. Epilepsia, 2009, 50: 411–412.
- Cereghino J.J., Brock J.T., Van Meter J.C., Penry J.K., Smith L.D., White B.G.: The efficacy of carbamazepine combinations in epilepsy. Clin. Pharmacol. Ther., 1975, 18: 733–741.
- Chez M.G., Bourgeois B.F., Pipenger C.E., Knowles W.D.: Pharmacodynamic interactions between phenytoin and valproate: individual and combined antiepileptic and neurotoxic actions in mice. Clin. Neuropharmacol., 1994, 17: 32–37.
- Chung S., Ben-Menachem E., Sperling M.R., Rosenfeld W., Foutain N., Benbadis S.: Examining the clinical utility of lacosamide: pooled analyses of three phase II/III clinical trials. CNS Drugs, 2010, 24: 1041–1054. doi: 10.2165/11586830-000000000-00000.
- Cuadrado A., Chevas D.L., Valdizan E.M., Armijo J.A.: Synergistic interaction between valproate and lamotrigine against seizures induced by 4-aminopyridine and pentylenetetrazole in mice. Eur. J. Pharmacol., 2002, 453: 43–52.
- Deckers C.L., Czuczwar S.J., Hekster Y.A., Keyser A., Kubova H., Meinardi H.: Selection of antiepileptic drug polytherapy based on mechanisms of action: the evidence reviewed. Epilepsia, 2000, 4: 1364–1374.
- Deckers C.L.P., Hekster T.A., Keyser A., van Lier H.J.J., Meinardi H., Renier W.O.: Monotherapy versus polytherapy for epilepsy: A multicenter double-blind randomized study. Epilepsia, 2001, 42: 1387–1394.
- Ferrendelli J.A.: Relating pharmacology to clinical practice: the pharmacologic basis of rational polypharmacy. Neurology, 1995, 45: 12–16.
- Flores L., Kemp S., Colbeck K., Moran N., Quirk J., Ramkolea P. et al: Clinical experience with oral lacosamide as adjunctive therapy in adult patients with uncontrolled epilepsy: A multicentre study in epilepsy clinics in the United Kingdom (UK). Seizure, 2012, 21: 512–517. http://www.ncbi.nlm.nih.gov/pubmed/7898740.
- French J.A., Faught E.: Rational polytherapy. Epilepsia, 2009, 50: 63–68. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19702736.
- Halasz P., Cramer J.A., Hodoba D., Czionkowska A., Guekht A., Maia J.: Long-term efficacy and safety of eslicarbazepine acetate: results of a 1-year open-label extension study in partial-onset seizures in adults with epilepsy. Epilepsia, 2010, 51: 1963–1969.
- Jonker D.M., Voskuyl R.A., Danhof M.: Synergistic combinations of anticonvulsant agents: what is the evidence from animal experiments? Epilepsia, 2007, 48: 412–434.
- Kwan P., Brodie M.J.: Early identification of refractory epilepsy. N. Engl. J. Med., 2000a, 342: 314–319.
- Kwan P., Brodie M.J.: Epilepsy after the first drug fails: substitution or add-on? Seizure, 2000b, 9: 464–468.
- Leach J.P., Brodie M.J.: Synergism with GABAergic drugs in refractory epilepsy. Lancet, 1994, 343: 1650.
- Luszczki J.J., Czuczwar P., Cioczek-Czuczwar A., Wojcik-Cwikla J., Ratnaraj N.: Interactions of lamotrigine with topiramate and first-generation antiepileptic drugs in the maximal electroshock test in mice: an isobolographic analysis. Epilepsia, 2003, 44: 1003–1013.
- Luszczki J.J., Czuczwar S.J.: Interaction between lamotrigine and felbamate in the maximal electroshock-induced seizures in mice: an isobolographic analysis. Eur. Neuropsychopharmacol., 2005, 15: 133–142.
- Margolis J.M., Chu B-C., Wang Z.J., Copher R., Cavazos J.E.: Effectiveness of antiepileptic drug combination therapy for partial-onset seizures based on mechanisms of action. JAMA Neurol., 2014, 71: 985–993. Available at: https://jamanetwork.com/journals/jamaneurology/articlepdf/1877433/noi140030.pdf.
- Masuda Y., Utsui Y., Shiraishi T., Karasawa T., Yoshida K., Shimizu M.: Evidence for a synergistic interaction between phenytoin and phenobarbital in experimental animals. J.Pharmacol. Exp. Ther., 1981, 217: 805–811.
- Mattson R.H., Cramer J.A., Collins J.F.: A comparison of valproate with carbamazepine for the treatment of complex partial seizures and secondarily generalized tonic-clonic seizures in adults. The Department of Veterans Affairs Epilepsy Cooperative Study No. 264 Group. N. Engl. J. Med., 1992, 327: 765–771.
- Mawer G.E., Pleuvry B.J.: Interactions involving new antiepileptic drugs. Pharmacol. Ther., 1995, 68: 209–231. Available at: http://www.ncbi.nlm.nih.gov/pubmed/8719968.
- Moeller J.J., Rahey S.R., Sadler R.M.: Lamotrigine-valproic acid combination therapy for medically refractory epilepsy. Epilepsia, 2009, 50: 475–479.
- Perucca E.: Clinically relevant drug interactions with antiepileptic drugs. Br. J. Clin. Pharmacol., 2006, 61: 246–255.
- Pisani F., Oteri G., Russo M.F., Di Perri R., Perruca E., Richens A.: The efficacy of valproate-lamotrigine comedication in refractory complex partial seizures: evidence for a pharmacodynamic interaction. Epilepsia, 1999, 40: 1141–1146.
- Reynolds E.H., Chadwick D., Galbraith A.W.: One drug (phenytoin) in the treatment of epilepsy. The Lancet, 1976, 307: 923–926.
- Reynolds E.H., Shorvon S.D.: Monotherapy or polytherapy for epilepsy? Epilepsia, 1981, 22: 1–10.
- Rowan A.J., de Beer-Pawlikowski N., van der Geest P., Meinardi H.: Valproate-ethosuximide combination therapy for refractory absence seizures. Arch. Neurol., 1983, 40: 797–802.
- Russmann V., Salvamoser J.D., Rettenbeck M.L., Komori T., Potschka H.: Synergism of perampanel and zonisamide in the rat amygdala kindling model of temporal lobe epilepsy. Epilepsia, 2016, 57: 638–647.
- Sake J-K., Herbert D., Isojarvi J., Doty P., De Backer M., Davies K. et al: A pooled analysis of lacosamide clinical trial data grouped by mechanism of action of concomitamt antiepileptic drugs. CNS Drugs, 2010, 24: 1055–1068.
- Shandra A., Shandra P., Kaschenko O., Matagne A., Stöhr T.: Synergism of lacosamide with established antiepileptic drugs in the 6-Hz seizure model in mice. Epilepsia, 2013, 54: 1167–1175.
- Shank R.P., Gardocki J.F., Vaught J.L., Schupski J.J., Raffa R.B.: Topiramate: preclinical evaluation of structurally novel anticonvulsant. Epilepsia, 1994, 35: 450–460.
- St Louis E.K.: Truly “rational” polytherapy: maximizing efficacy and minimizing drug interactions, drug load, and adverse effects. Curr. Neuropharmacol., 2009, 7: 96–105.
- Stephen L.J., Brodie M.J.: Seizure freedom with more than one antiepileptic drug. Seizure, 2002, 11: 349–351.
- Stephen L.J., Sills, G.J., Brodie M.J.: Lamotrigine and topiramate may be a useful combination. Lancet, 1998, 351: 958–959.
- Walker J.E., Koon R.: Carbamazepine versus valproate versus combine therapy for refractory partial complex seizures with secondary generalization. Epilepsia, 1988, 29: 693 (abst).