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Axillary adenopathy after COVID-19 vaccine in patients undergoing breast ultrasound Cover

Figures & Tables

Fig. 1.

Example of vaccine-associated adenopathy in a 66-year-old female patient undergoing breast ultrasound for routine breast imaging with history of breast cancer in the left breast. A. US in the left shoulder showing left axillary adenopathy (22 mm) with fatty hilum and thickened cortex. B. A core biopsy was performed. C. The histology was negative for lymph node malignancy (normal lymphocytes and histiocytes in hematoxylin-eosin staining)
Example of vaccine-associated adenopathy in a 66-year-old female patient undergoing breast ultrasound for routine breast imaging with history of breast cancer in the left breast. A. US in the left shoulder showing left axillary adenopathy (22 mm) with fatty hilum and thickened cortex. B. A core biopsy was performed. C. The histology was negative for lymph node malignancy (normal lymphocytes and histiocytes in hematoxylin-eosin staining)

Fig. 2.

Example of vaccine-associated adenopathy in a 29-year-old female undergoing breast ultrasound for routine breast imaging due to increased breast density. A. US in the left shoulder showing asymmetric left axillary adenopathy (18 mm) with preserved fatty hilum but irregular cortex. B. Four-week follow-up: axillary sonography of the same patient demonstrates decreased size (13 cm) and some residual cortical thickening. C. Eight-week follow-up: axillary ultrasound shows normal sized lymph node
Example of vaccine-associated adenopathy in a 29-year-old female undergoing breast ultrasound for routine breast imaging due to increased breast density. A. US in the left shoulder showing asymmetric left axillary adenopathy (18 mm) with preserved fatty hilum but irregular cortex. B. Four-week follow-up: axillary sonography of the same patient demonstrates decreased size (13 cm) and some residual cortical thickening. C. Eight-week follow-up: axillary ultrasound shows normal sized lymph node

Breast ultrasound features of axillary lymph nodes

Number of patientPatient age (years)Previous breast cancerUS feature axillary lymph node: axillary lymph node sideUS feature axillary lymph node: size (mm of short-axis)US feature axillary lymph node: focal cortical thickeningUS feature axillary lymph node: visible hilar fatUS BI-RADSPerformed biopsyHistology after biopsyVaccination dateUS date
129NoLeft18NoYesE3NoNo02/202103/2021
266Yes: in 2017 IDC in left breast with negative ipsilateral axillary lymph nodesLeft22NoYesE4bYesnormal lymphocytes and histiocytes in hematoxylin-eosin staining02/202103/2021
334NoRight11YesYesE3No 02/202103/2021
454Yes: in 2015 DCIS in left breast with negative ipsilateral axillary lymph nodesLeft23NoYesE4bYesnormal lymphocytes and histiocytes in hematoxylin-eosin staining03/202104/2021
574NoLeft15YesYesE3No 03/202104/2021
646Yes: in 2018 IDC in left breast with negative ipsilateral axillary lymph nodesLeft13YesYesE4bYesnormal lymphocytes and histiocytes in hematoxylin-eosin staining03/202105/2021
776Yes: in 2018 IDC in right breast with negative ipsilateral axillary lymph nodesRight20NoYesE4bYesnormal lymphocytes and histiocytes in hematoxylin-eosin staining04/202105/2021
859Yes: in 2020 IDC in left breast with negative ipsilateral axillary lymph nodesLeft20NoYesE4bYesnormal lymphocytes and histiocytes in hematoxylin-eosin staining04/202105/2021
939NoLeft22NoYesE3No 05/202105/20121
1028NoRight20YesYesE3No 05/202105/2021
DOI: https://doi.org/10.15557/jou.2021.0060 | Journal eISSN: 2451-070X | Journal ISSN: 2084-8404
Language: English
Page range: 361 - 364
Submitted on: Jun 22, 2021
Accepted on: Nov 5, 2021
Published on: Dec 15, 2021
Published by: MEDICAL COMMUNICATIONS Sp. z o.o.
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2021 Sara De Giorgis, Alessandro Garlaschi, Nicole Brunetti, Simona Tosto, Giuseppe Rescinito, Francesco Monetti, Claudio Oddone, Barbara Massa, Francesca Pitto, Massimo Calabrese, Alberto Stefano Tagliafico, published by MEDICAL COMMUNICATIONS Sp. z o.o.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.