Reliability of knee joint sonography in the evaluation of gouty arthritis

Anjum, Zafar Iqbal; Bacha, Raham; Manzoor, Iqra; Gilani, Syed Amir

doi:10.15557/jou.2021.0051

Abstract

Objective: To determine the reliability of knee joint sonography in the evaluation of gouty arthritis. Methodology: A search of Google Scholar, PubMed, NCBI, MEDLINE, and Medscape databases, from 1988 up to 2020. The key search terms used were knee joint; knee joint ultrasound; gout; gouty arthritis, knee joint pain; sensitivity; specificity. The reviewer independently screened the titles and abstracts of the relevant articles and full-text downloads to determine whether the inclusion or exclusion criteria were met. Results: In total, 103 articles were identified through the database search. In addition, 11 articles were identified through other sources. Then, screening was performed, and 9 articles were removed due to duplication. Further screening was done for 105 articles, and 27 articles were excluded due to insufficient information. Seventy-eight full-text articles were assessed for eligibility. A total of 13 full-text articles were excluded due to research performed on animals, as the study had been designed as a review of only human studies. Sixty-three studies were included that had a qualitative synthesis. Conclusion: The knee is a weight-bearing joint and may be affected by a myriad of different pathological conditions, therefore a proper diagnosis is of prime importance for a proper management plan. Ultrasound is a non-invasive, radiation-free, and readily available modality that has high sensitivity and specificity in the evaluation of gouty arthritis.

References

Sudoł-Szopińska I, Pracoń G: Diagnostic imaging of psoriatic arthritis. Part II: magnetic resonance imaging and ultrasonography. J Ultrason 2016; 16: 163–174.
Search in Google Scholar Back to article
Singh K, Gupta K, Kaur S: High resolution ultrasonography of the tibial nerve in diabetic peripheral neuropathy. J Ultrason 2017; 17: 246–252.
Search in Google Scholar Back to article
Richette P, Bardin T: Gout. Lancet 2010; 375: 318–328.
Search in Google Scholar Back to article
Sudoł-Szopińska I, Jans L, Teh J: Rheumatoid arthritis: what do MRI and ultrasound show. J Ultrason 2017; 17: 5–16.
Search in Google Scholar Back to article
Perez-Ruiz F, Dalbeth N, Urresola A, de Miguel E, Schlesinger N: Imaging of gout: findings and utility. Arthritis Res Ther 2009; 11: 232.
Search in Google Scholar Back to article
Wright SA, Filippucci E, McVeigh C, Grey A, McCarron M, Grassi W et al.: High-resolution ultrasonography of the first metatarsal phalangeal joint in gout: a controlled study. Ann Rheum Dis 2007; 66: 859–864.
Search in Google Scholar Back to article
Thiele RG, Schlesinger N: Diagnosis of gout by ultrasound. Rheumatology 2007; 46: 1116–1121.
Search in Google Scholar Back to article
Filippucci E, Gutierrez M, Georgescu D, Salaffi F, Grassi W: Hyaline cartilage involvement in patients with gout and calcium pyrophosphate deposition disease. An ultrasound study. Osteoarthritis Cartilage 2009; 17: 178–181.
Search in Google Scholar Back to article
Sconfienza L, Silvestri E, Bartolini B, Garlaschi G, Cimmino MA: Sonoelastography may help in the differential diagnosis between rheumatoid nodules and tophi. Clin Exp Rheumatol 2010; 28: 144–145.
Search in Google Scholar Back to article
Neogi T, Jansen TLTA, Dalbeth N, Fransen J, Schumacher HR, Berendsen D et al.: 2015 gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheumatol 2015; 67: 2557–2568.
Search in Google Scholar Back to article
Dalbeth N, Doyle A, McQueen FM: Imaging in gout: insights into the pathological features of disease. Curr Opin Rheumatol 2012; 24: 132–138.
Search in Google Scholar Back to article
Das S, Ghosh A, Ghosh P, Lahiri D, Sinhamahapatra P, Basu K: Sensitivity and specificity of ultrasonographic features of gout in intercritical and chronic phase. Int J Rheum Dis 2017; 20: 887–893.
Search in Google Scholar Back to article
Ogdie A, Taylor WJ, Weatherall M, Fransen J, Jansen TL, Neogi T et al.: Imaging modalities for the classification of gout: systematic literature review and meta-analysis. Ann Rheum Dis 2015; 74: 1868–1874.
Search in Google Scholar Back to article
Thiele RG: Role of ultrasound and other advanced imaging in the diagnosis and management of gout. Curr Rheum Rep 2011; 13: 146–153.
Search in Google Scholar Back to article
Gutierrez M, Schmidt WA, Thiele RG, Keen HI, Kaeley GS, Naredo E et al.: International consensus for ultrasound lesions in gout: results of Delphi process and web-reliability exercise. Rheumatology 2015; 54: 1797–1805.
Search in Google Scholar Back to article
Chowalloor PV, Keen HI: A systematic review of ultrasonography in gout and asymptomatic hyperuricaemia. Ann Rheum Dis 2013; 72: 638–645.
Search in Google Scholar Back to article
Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP et al.: The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 2009; 62: e1–e34.
Search in Google Scholar Back to article
Ogdie A, Taylor WJ, Neogi T, Fransen J, Jansen TL, Schumacher HR et al.: Performance of ultrasound in the diagnosis of gout in a multicenter study: comparison with monosodium urate monohydrate crystal analysis as the gold standard. Arthritis Rheumatol 2017; 69: 429–438.
Search in Google Scholar Back to article
Elsaman AM, Muhammad EM, Pessler F: Sonographic findings in gouty arthritis: diagnostic value and association with disease duration. Ultrasound Med Biol 2016; 42: 1330–1136.
Search in Google Scholar Back to article
Löffler C, Sattler H, Peters L, Löffler U, Uppenkamp M, Bergner R: Distinguishing gouty arthritis from calcium pyrophosphate disease and other arthritides. J Rheumatol 2015; 42: 513–520.
Search in Google Scholar Back to article
Grassi W, Filippucci E, Farina A, Salaffi F, Cervini C: Ultrasonography in the evaluation of bone erosions. Ann Rheum Dis 2001; 60: 98–104.
Search in Google Scholar Back to article
Cajas LJ, Casallas A, Medina YF, Quintana G, Rondón F: Pannus and rheumatoid arthritis: historic and pathophysiological evolution. Rev Colomb Reumatol 2019; 26: 118–128.
Search in Google Scholar Back to article
Nalbant S, Corominas H, Hsu B, Chen LX, Schumacher HR, Kitumnuaypong T: Ultrasonography for assessment of subcutaneous nodules. J Rheumatol 2003; 30: 1191–1195.
Search in Google Scholar Back to article
Grassi W, Meenagh G, Pascual E, Filippucci E: „Crystal clear”-sonographic assessment of gout and calcium pyrophosphate deposition disease. Semin Arthritis Rheum 2006; 36: 197–202.
Search in Google Scholar Back to article
Rettenbacher T, Ennemoser S, Weirich H, Ulmer H, Hartig F, Klotz W et al.: Diagnostic imaging of gout: comparison of high-resolution US versus conventional X-ray. Eur Radiol 2008; 18: 621–630.
Search in Google Scholar Back to article
Iagnocco A, Ceccarelli F, Perricone C, Valesini G: The role of ultrasound in rheumatology. Semin Ultrasound CT MRI 2011; 32: 66–73.
Search in Google Scholar Back to article
Carter JD, Kedar RP, Anderson SR, Osorio AH, Albritton NL, Gnanashanmugam S et al.: An analysis of MRI and ultrasound imaging in patients with gout who have normal plain radiographs. Rheumatology 2009; 48: 1442–1446.
Search in Google Scholar Back to article
Filippucci E, Scirè CA, Delle Sedie A, Iagnocco A, Riente L, Meenagh G et al.: Ultrasound imaging for the rheumatologist XXV. Sonographic assessment of the knee in patients with gout and calcium pyrophosphate deposition disease. Clin Exp Rheumatol 2010; 28: 2–5.
Search in Google Scholar Back to article
Pineda C, Amezcua-Guerra LM, Solano C, Rodriguez-Henríquez P, Hernández-Díaz C, Vargas A et al.: Joint and tendon subclinical involvement suggestive of gouty arthritis in asymptomatic hyperuricemia: an ultrasound controlled study. Arthritis Res Ther 2011; 13: R4.
Search in Google Scholar Back to article
Howard RG, Pillinger MH, Gyftopoulos S, Thiele RG, Swearingen CJ, Samuels J: Reproducibility of musculoskeletal ultrasound for determining monosodium urate deposition: concordance between readers. Arthritis Care Res 2011; 63: 1456–1462.
Search in Google Scholar Back to article
de Ávila Fernandes E, Kubota ES, Sandim GB, Mitraud SA, Ferrari AJ, Fernandes AR: Ultrasound features of tophi in chronic tophaceous gout. Skeletal Radiol 2011; 40: 309–315.
Search in Google Scholar Back to article
De Miguel E, Puig JG, Castillo C, Peiteado D, Torres RJ, Martín-Mola E: Diagnosis of gout in patients with asymptomatic hyperuricaemia: a pilot ultrasound study. Ann Rheum Dis 2012; 71: 157–158.
Search in Google Scholar Back to article
Filippucci E, Meenagh G, Delle Sedie A, Sakellariou G, Iagnocco A, Riente L et al.: Ultrasound imaging for the rheumatologist XXXVI. Sonographic assessment of the foot in gout patients. Clin Exp Rheumatol 2011; 29: 901–905.
Search in Google Scholar Back to article
Ottaviani S, Allard A, Bardin T, Richette P: An exploratory ultrasound study of early gout. Clin Exp Rheumatol 2011; 29: 816–821.
Search in Google Scholar Back to article
Choi HK, Burns LC, Shojania K, Koenig N, Reid G, Abufayyah M et al.: Dual energy CT in gout: a prospective validation study. Ann Rheum Dis 2012; 71: 1466–1471.
Search in Google Scholar Back to article
Dalbeth N, Schauer C, MacDonald P, Perez-Ruiz F, Schumacher HR, Hamburger S et al.: Methods of tophus assessment in clinical trials of chronic gout: a systematic literature review and pictorial reference guide. Ann Rheum Dis 2011; 70: 597–604.
Search in Google Scholar Back to article
Glazebrook KN, Guimarães LS, Murthy NS, Black DF, Bongartz T, Manek NJ et al.: Identification of intraarticular and periarticular uric acid crystals with dual-energy CT: initial evaluation. Radiology 2011; 261: 516–524.
Search in Google Scholar Back to article
Roddy E, Menon A, Hall A, Datta P, Packham J: Polyarticular sonographic assessment of gout: a hospital-based cross-sectional study. Joint Bone Spine 2013; 80: 295–300.
Search in Google Scholar Back to article
McQueen FM, Reeves Q, Dalbeth N: New insights into an old disease: advanced imaging in the diagnosis and management of gout. Postgrad Med J 2013; 89: 87–93.
Search in Google Scholar Back to article
Ottaviani S, Richette P, Allard A, Ora J, Bardin T: Ultrasonography in gout: a case-control study. Clin Exp Rheumatol 2012; 30: 499–504.
Search in Google Scholar Back to article
Girish G, Melville DM, Kaeley GS, Brandon CJ, Goyal JR, Jacobson JA et al.: Imaging appearances in gout. Arthritis 2013; 2013.
Search in Google Scholar Back to article
Bergner R, Peters L, Schmitt V, Sattler H, Löffler C: SAT0382 Arthrosonographic Findings in Crystal Arthropathies. Ann Rheum Dis 2013; 72 (Suppl 3): A713.
Search in Google Scholar Back to article
Huppertz A, Hermann K-GA, Diekhoff T, Wagner M, Hamm B, Schmidt WA: Systemic staging for urate crystal deposits with dual-energy CT and ultrasound in patients with suspected gout. Rheumatol Int 2014; 34: 763–771.
Search in Google Scholar Back to article
Zhang Q, Gao F, Sun W, Ma J, Cheng L, Li Z: The diagnostic performance of musculoskeletal ultrasound in gout: a systematic review and meta-analysis. PloS One 2018; 13: e0199672.
Search in Google Scholar Back to article
Lamers-Karnebeek F, Van Riel P, Jansen T: Additive value for ultrasonographic signal in a screening algorithm for patients presenting with acute mono-/oligoarthritis in whom gout is suspected. Clin Rheumatol 2014; 33: 555–559.
Search in Google Scholar Back to article
Naredo E, Uson J, Jiménez-Palop M, Martínez A, Vicente E, Brito E et al.: Ultrasound-detected musculoskeletal urate crystal deposition: which joints and what findings should be assessed for diagnosing gout? Ann Rheum Dis 2014; 73: 1522–1528.
Search in Google Scholar Back to article
Atik OŞ, Ergişi Y, Ayanoğlu T, Tokgöz MA, Sezgin EA, Göçün PU: Is it easy to clinically distinguish inflammatory arthritis of bacterial origin from monoarthritis attacks of gout disease? Eklem Hastalik Cerrahisi 2016; 27: 167–170.
Search in Google Scholar Back to article
Zufferey P, Valcov R, Fabreguet I, Dumusc A, Omoumi P, So A: A prospective evaluation of ultrasound as a diagnostic tool in acute microcrystalline arthritis. Arthritis Res Ther 2015; 17: 188.
Search in Google Scholar Back to article
Bongartz T, Glazebrook KN, Kavros SJ, Murthy NS, Merry SP, Franz WB et al.: Dual-energy CT for the diagnosis of gout: an accuracy and diagnostic yield study. Ann Rheum Dis 2015; 74: 1072–1077.
Search in Google Scholar Back to article
Diekhoff T, Ziegeler K, Feist E, Kiefer T, Mews J, Hamm B et al.: First experience with single-source dual-energy computed tomography in six patients with acute arthralgia: a feasibility experiment using joint aspiration as a reference. Skeletal Radiol 2015; 44: 1573–1577.
Search in Google Scholar Back to article
Das S, Goswami RP, Ghosh A, Ghosh P, Lahiri D, Basu K: Temporal evolution of urate crystal deposition over articular cartilage after successful urate-lowering therapy in patients with gout: an ultrasonographic perspective. Mod Rheumatol 2017; 27: 518–523.
Search in Google Scholar Back to article
Zhu L, Zheng S, Wang W, Zhou Q, Wu H: Combining hyperechoic aggregates and the double-contour sign increases the sensitivity of sonography for detection of monosodium urate deposits in gout. J Ultrasound Med 2017; 36: 935–940.
Search in Google Scholar Back to article
Ahmad Z, Gupta AK, Sharma R, Bhalla AS, Kumar U, Sreenivas V: Dual energy computed tomography: a novel technique for diagnosis of gout. Int J Rheum Dis 2016; 19: 887–896.
Search in Google Scholar Back to article
Ventura-Ríos L, Sánchez-Bringas G, Pineda C, Hernández-Díaz C, Reginato A, Alva M et al.: Tendon involvement in patients with gout: an ultrasound study of prevalence. Clin Rheumatol 2016; 35: 2039–2044.
Search in Google Scholar Back to article
Stewart S, Dalbeth N, Vandal AC, Allen B, Miranda R, Rome K: Are ultrasound features at the first metatarsophalangeal joint associated with clinically-assessed pain and function? A study of people with gout, asymptomatic hyperuricaemia and normouricaemia. J Foot Ankle Res 2017; 10: 22.
Search in Google Scholar Back to article
Stewart S, Dalbeth N, Vandal AC, Allen B, Miranda R, Rome K: Ultrasound features of the first metatarsophalangeal joint in gout and asymptomatic hyperuricemia: comparison with normouricemic individuals. Arthritis Care Res 2017; 69: 875–883.
Search in Google Scholar Back to article
Lee YH, Song GG: Diagnostic accuracy of ultrasound in patients with gout: a meta-analysis. Semin Arthritis Rheum 2018; 47: 703–709.
Search in Google Scholar Back to article
Pattamapaspong N, Vuthiwong W, Kanthawang T, Louthrenoo W: Value of ultrasonography in the diagnosis of gout in patients presenting with acute arthritis. Skeletal Radiol 2017; 46: 759–767.
Search in Google Scholar Back to article
Tekaya R, Tekaya AB, Saidane O, Said HB, Gaja A, Sahli H et al.: Tophaceous hip gouty arthritis revealing asymptomatic axial gout. Egyptian Rheumatol 2018; 40: 209–212.
Search in Google Scholar Back to article
Bhadu D, Das SK, Wakhlu A, Dhakad U, Sharma M: Ultrasonographic detection of double contour sign and hyperechoic aggregates for diagnosis of gout: two sites examination is as good as six sites examination. Int J Rheum Dis 2018; 21: 523–531.
Search in Google Scholar Back to article
Gamala M, Linn-Rasker S, Nix M, Heggelman B, Van Laar J, Pasker-de Jong P et al.: Gouty arthritis: decision-making following dual-energy CT scan in clinical practice, a retrospective analysis. Clin Rheumatol 2018; 37: 1879–1884.
Search in Google Scholar Back to article
Dalbeth N, Doyle AJ: Imaging tools to measure treatment response in gout. Rheumatology 2018; 57 (suppl_1): i27–i34.
Search in Google Scholar Back to article
Jia E, Zhu J, Huang W, Chen X, Li J: Dual-energy computed tomography has limited diagnostic sensitivity for short-term gout. Clin Rheumatol 2018; 37: 773–777.
Search in Google Scholar Back to article
Ramon A, Bohm-Sigrand A, Pottecher P, Richette P, Maillefert J-F, Devilliers H et al.: Role of dual-energy CT in the diagnosis and follow-up of gout: systematic analysis of the literature. Clin Rheumatol 2018; 37: 587–595.
Search in Google Scholar Back to article
Di Matteo A, Filippucci E, Cipolletta E, Musca A, Di Donato E, Martire V et al.: Ultrasound and clinical features of hip involvement in patients with gout. Joint Bone Spine 2019; 86: 633–666.
Search in Google Scholar Back to article
Cazenave T, Martire V, Reginato AM, Gutierrez M, Waimann CA, Pineda C et al.: Reliability of OMERACT ultrasound elementary lesions in gout: results from a multicenter exercise. Rheumatol Int 2019; 39: 707–713.
Search in Google Scholar Back to article
Murayama M, Nishida M, Kudo Y, Deguchi T, Marukawa K, Fujieda Y et al.: Case with long-standing gout showing various ultrasonographic features caused by monosodium urate monohydrate crystal deposition. Modern Rheumatology Case Rep 2020; 4: 110–115.
Search in Google Scholar Back to article
Micu MC, Dogaru BG: Monstrous gout devastating hands and feet. Clin Rheumatol 2019; 38: 3309–3310.
Search in Google Scholar Back to article
Persons B, Kissin EY: Scruples over speckles. J Med Ultrasound 2020; 28: 179–180.
Search in Google Scholar Back to article
Sakellariou G, Scirè CA, Adinolfi A, Batticciotto A, Bortoluzzi A, Delle Sedie A et al.: Differential diagnosis of inflammatory arthropathies by musculoskeletal ultrasonography: a systematic literature review. Front Med 2020; 7: 141.
Search in Google Scholar Back to article
Scirocco C, Rutigliano IM, Finucci A, Iagnocco A: Musculoskeletal ultrasonography in gout. Med Ultrason 2015; 17: 535–540.
Search in Google Scholar Back to article

Reliability of knee joint sonography in the evaluation of gouty arthritis

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