Fig. 1.
Fig. 2.
The comparison of lipid profiles, atherogenic lipid indicates and carotid intima-media thickness in the non-obese children and the obese children divided according to the value of TSH level
| Variable | Non-obese children (n = 38) | Obese children | ||
|---|---|---|---|---|
| Total (n = 110) | TSH ≤4 μIU/ml (n = 104) | TSH >4 μIU/ml (n = 5) | ||
| TC (mg/dl) | 156.77 ± 23.85 | 177.47 ± 29.52*** | 176.4 ± 29.18 | 196.0 ± 31.79 |
| HDL-C (mg/dl) | 54 (33–92) | 42 (25–92)*** | 42 (25–92) | 49.5 (30–58) |
| LDL-C (mg/dl) | 84.26 ± 25.64 | 106.31 ± 27.19*** | 105.58 ± 27.01 | 119.0 ± 29.66 |
| TG (mg/dl) | 73 (23–167) | 124 (39–458)*** | 123 (39–458) | 162.5 (106–219) |
| TG/HDL-C | 1.29 (0.33–4.28) | 2,99 (0.53–14.31)*** | 2.99 (0.53–14.31) | 3.75 (2.0–6,1) |
| LDL C/HDL C | 1.56 (0.09–3.03) | 2.47 (0.7–6.76)*** | 2.44 (0.7–6.76) | 2.64 (1,71–5.0) |
| TC/HDL-C | 2.94 (1.36–4.87) | 4.16 (2.0–10.32)*** | 4.16 (2.0–10.32) | 4.29 (3.29–7.23) |
| IMT | 0.58 (0.25–0.73) | 0.6 (0.22–1.4) | 0.6 (0.22–1.4) | 0.65 (0.5–0.7) |
Multivariate regression analysis of intima-media thickness (dependent variable)
| Independent variables | B | SE | p-value | 95% CI |
|---|---|---|---|---|
| MODEL 1 | ||||
| Age (years) | 0.008 | 0.007 | 0.258 | −0.006−0.021 |
| Sex (male = 1/female = 2) | −0.052 | 0.036 | 0.153 | −0.124−0.019 |
| SDS BMI | 0,.047 | 0.041 | 0.259 | −0.034−0.127 |
| TSH (μIU/ml) | 0.041 | 0.020 | 0.041 | 0.003−0.080 |
| MODEL 2 | ||||
| Age (years) | 0.008 | 0.007 | 0.282 | −0.006−0.022 |
| Sex (male = 1/female = 2) | −0.052 | 0.038 | 0.0170 | −0.126−0.022 |
| SDS BMI | 0.049 | 0.043 | 0.255 | −0.035−0.134 |
| TC (mg/dl) | 0.000 | 0.002 | 0.844 | −0.004−0.004 |
| LDL-C (mg/dl) | 0.000 | 0.002 | 0.838 | −0.005−0.004 |
| TG (mg/dl) | 0.000 | 0.000 | 0.878 | −0.001−0.001 |
| TSH (μIU/ml) | 0.040 | 0.021 | 0.058 | −0.001−0.081 |