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Role of lung ultrasound in diagnosing and differentiating transient tachypnea of the newborn and respiratory distress syndrome in preterm neonates Cover

Role of lung ultrasound in diagnosing and differentiating transient tachypnea of the newborn and respiratory distress syndrome in preterm neonates

Open Access
|Feb 2022

Figures & Tables

Fig. 1

USG appearance of normal lung – which appears hypoechoic with visible pleural and A-lines. Curvilinear echogenic ribs are also seen, casting posterior acoustic shadowing
USG appearance of normal lung – which appears hypoechoic with visible pleural and A-lines. Curvilinear echogenic ribs are also seen, casting posterior acoustic shadowing

Fig. 2

Area of subpleural consolidation with air bronchograms
Area of subpleural consolidation with air bronchograms

Fig. 3

White out lung arising from 3-mm apart confluent B-lines and represents alveolar edema
White out lung arising from 3-mm apart confluent B-lines and represents alveolar edema

Fig. 4

Alveolar-interstitial syndrome, characterized by abnormal B-lines which are echogenic ring down artifacts, and are 7 mm apart arising from the pleural line and are representative of edema involving interlobular septa
Alveolar-interstitial syndrome, characterized by abnormal B-lines which are echogenic ring down artifacts, and are 7 mm apart arising from the pleural line and are representative of edema involving interlobular septa

Fig. 5

Double lung point sign, a sharp cutoff point arising due to more compact B-lines in lower and less compact B-lines in upper lung fields
Double lung point sign, a sharp cutoff point arising due to more compact B-lines in lower and less compact B-lines in upper lung fields

General information about patients in the two groups

Neonate groupGA (weeks)weight Birth (GMS)Gender (M/F)CS (n)
RDS (n = 50)31.3 ± 2.41511 ± 04928/2232
TTN (n = 50)33.0 ± 1.62030 ± 51031/1933

Distribution of ultrasound findings in the two groups

Ultrasound findingsRDS (n group = 50)TTN (n = group 50)p value
Consolidation bronchograms with air or fluid50 (100%)0<0.001*
Double lung point sign0 (0%)43 (86%)<0.001*
White out lungs (severe alveolar-interstitial syndrome)/Absent A-lines44 (88%)3 (6%)<0.001*
Interstitial syndrome06 (12%)47 (94%)<0.001*
Absence of spared areas50 (100%)3(6%)<0.001*
Pleural effusion bilateral – unilateral/09 (18%)05 (10%)>0.05**
Pleural line abnormalities50 (100%)50 (100%)>0.05**

USG findings in the TTN group

LUS findings in TTNObservations
SensitivitySpecificityPPVNPV
Double (DLP) sign lung point94.00%100%100%94.3%
Alveolar-syndrome interstitial94.0%88.0%88.7%93.6%
Pleural line abnormalities100%0%50%-
Absent White out A-lines/ lungs6.00%0%5.7%0%
Pleural effusion10.0%82.0%35.7%47.7%

USG findings in the RDS group

LUS findings in RDSObservations
SensitivitySpecificityPPVNPV
Consolidation or fluid bronchograms with air100%100%100%100%
White out lungs (severe alveolar-interstitial syndrome)/Absent A-lines88.0%94.0%93.6%88.7%
Absence of spared areas100%94.0%94.3%100%
Pleural line abnormalities100%0%50%-
Pleural effusion18.0%90.0%64.2%52.3%
DOI: https://doi.org/10.15557/JoU.2022.0001 | Journal eISSN: 2451-070X | Journal ISSN: 2084-8404
Language: English
Page range: 1 - 5
Submitted on: Nov 20, 2021
Accepted on: Dec 16, 2021
Published on: Feb 8, 2022
Published by: MEDICAL COMMUNICATIONS Sp. z o.o.
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2022 Srinivasan S, Neeti Aggarwal, Sushma Makhaik, Anupam Jhobta, Sumala Kapila, Rohit Bhoil, published by MEDICAL COMMUNICATIONS Sp. z o.o.
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.