Computational Fluid Dynamics Methods and Their Applications in Medical Science

Kowalewski, Wojciech; Roszak, Magdalena; Kołodziejczak, Barbara; Ren-Kurc, Anna; Bręborowicz, Andrzej

doi:10.1515/slgr-2016-0047

Abstract

As defined by the National Institutes of Health: “Biomedical engineering integrates physical, chemical, mathematical, and computational sciences and engineering principles to study biology, medicine, behavior, and health”. Many issues in this area are closely related to fluid dynamics. This paper provides an overview of the basic concepts concerning Computational Fluid Dynamics and its applications in medicine.

References

Allen, M. P. (2004). Introduction to Molecular Dynamics Simulation. In N. Attig, K. Binder, H. Grubmüller, & K. Kremer (Eds.), Computational Soft Matter: From Synthetic Polymers to Proteins, Lecture Notes, NIC Series Volume 23 (pp. 1–28). Jülich: John von Neumann Institute for Computing (NIC).
Search in Google Scholar Back to article
Chandran, K. B., Rittgers, S. E., & Yoganathan, A. P. (2012). Biofluid Mechanics: The Human Circulation (Second Edition). Boca-Raton: CRC Press.10.1201/b11709
Search in Google Scholar Back to article
de Lima e Silva, A. L. F., da Silva, A. R., & da Silveira-Neto, A. (2007). Numerical simulation of two-dimensional complex flows around bluff bodies using the immersed boundary method. Journal of the Brazilian Society of Mechanical Sciences and Engineering, 29(4), 379–387.
Search in Google Scholar Back to article
Frenkel, D. & Smit, B. (2001). Understanding Molecular Simulation: From Algorithms to Applications. Computational Science. San Diego, San Francisco, New York, Boston, London, Sydney, Tokyo: Academic Press.
Search in Google Scholar Back to article
Jarmuła, A. (2013). Dynamika molekularna: charakterystyka podstawowa, metody i zastosowanie w projektowaniu leków. Retrieved from http://www.ebiotechnologia.pl/Artykuly/Dynamika-molekularna-charakterystyka-podstawowametodyi-zastosowanie--w-projektowaniu-lekow/
Search in Google Scholar Back to article
Lemkul, J. A. (2013). GROMACS Tutorial, Lysozyme in Water. Retrieved from http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin/gmxtutorials/lysozyme/
Search in Google Scholar Back to article
Marić, T., Höpken, J., & Mooney, K. (2014). The OpenFOAM Technology Primer. Sourceflux UG.
Search in Google Scholar Back to article
Pozrikidis, C. (2010). Computational Hydrodynamics of Capsules and Biological Cells. Series: Chapman & Hall/CRC Mathematical and Computational Biology (Book 35). Boca Raton: CRC Press.10.1201/EBK1439820056
Search in Google Scholar Back to article
Price, J. F. (2006). Lagrangian and Eulerian Representations of Fluid Flow: Kinematics and the Equations of Motion. Retrieved from http://www.whoi.edu/science/PO/people/jprice/class/ELreps.pdf
Search in Google Scholar Back to article
Rubenstein, D., Yin, W., & Frame, M. D. (2015). Biofluid Mechanics: An Introduction to Fluid Mechanics, Macrocirculation, and Microcirculation. Biomedical Engineering. Academic Press Series in Biomedical Engineering.
Search in Google Scholar Back to article
Spagnolie, S. E. (Ed.). (2015). Complex Fluids in Biological Systems: Experiment, Theory, and Computation. Biological and Medical Physics, Biomedical Engineering. New York: Springer.10.1007/978-1-4939-2065-5
Search in Google Scholar Back to article
Spiegelman, M. (2000). Myths & Methods in Modeling. Retrieved from http://www.ldeo.columbia.edu/~mspieg/mmm/course.pdf
Search in Google Scholar Back to article
Tautermann, C. S., Seeliger, D., & Kriegl, J. M. (2015). What can we learn from molecular dynamics simulations for GPCR drug design? Computational and Structural Biotechnology Journal, 13, 111–121.10.1016/j.csbj.2014.12.002
Search in Google Scholar Back to article
Tu, J., Inthavong, K., & Ahmadi, G. (2013). Computational Fluid and Particle Dynamics in the Human Respiratory System. Biological and Medical Physics, Biomedical Engineering. New York: Springer.10.1007/978-94-007-4488-2
Search in Google Scholar Back to article
Tu, J., Inthavong, K., & Wong, K. K. L. (2015). Computational Hemodynamics – Theory, Modelling and Applications. New York: Springer.10.1007/978-94-017-9594-4
Search in Google Scholar Back to article
Versteeg, H., & Malalasekera, W. (2007). An Introduction to Computational Fluid Dynamics: The Finite Volume Method (2nd Edition). England: Pearson.
Search in Google Scholar Back to article
Zhao, H., & Caflisch, A. (2015). Molecular dynamics in drug design. European Journal of Medicinal Chemistry, 91, 4–14.10.1016/j.ejmech.2014.08.004
Search in Google Scholar Back to article

Computational Fluid Dynamics Methods and Their Applications in Medical Science

Abstract

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