Have a personal or library account? Click to login
Expression Of The Bcl2 Gene In Chronic Lymphocytic Leukaemia Patients Cover

References

  1. 1. Sagatys EM, Zhang L. Clinical and laboratory prognostic indicators in chronic lymphocytic leukemia. Cancer Control 2012;19(1):18-25.10.1177/10732748120190010322143059
  2. 2. Chiorazzi N. Implications of new prognostic markers in chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2012;2012:76-87.10.1182/asheducation.V2012.1.76.3806845
  3. 3. Obermann EC, Went P, Tzankov A, et al. Cell cycle phase distribution analysis in chronic lymphocytic leukaemia: a significant number of cells reside in early G1-phase. J Clin Pathol 2007;60(7):794-7.10.1136/jcp.2006.040956199579516950856
  4. 4. Thomadaki H, Scorilas A. BCL2 family of apoptosis-related genes: functions and clinical implications in cancer. Crit Rev Clin Lab Sci 2006;43(1):1-67.10.1080/1040836050029562616531274
  5. 5. Garrido C, Galluzzi L, Brunet M, et al. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ 2006;13(9):1423-33.10.1038/sj.cdd.440195016676004
  6. 6. Leibowitz B, Yu J. Mitochondrial signaling in cell death via the Bcl-2 family. Cancer Biol Ther 2010;9(6):417-22.10.4161/cbt.9.6.11392287411620190564
  7. 7. Burlacu A. Regulation of apoptosis by Bcl-2 family proteins. J Cell Mol Med 2003;7(3):249-57.10.1111/j.1582-4934.2003.tb00225.x674133514594549
  8. 8. Tzifi F, Economopoulou C, Gourgiotis D, et al. The Role of BCL2 Family of Apoptosis Regulator Proteins in Acute and Chronic Leukemias. Adv Hematol 2012;2012:524308.10.1155/2012/524308317372821941553
  9. 9. Mariano MT, Moretti L, Donelli A, et al. bcl-2 gene expression in hematopoietic cell differentiation. Blood 1992;80(3):768-75.10.1182/blood.V80.3.768.768
  10. 10. Meijerink JP. t(14;18), a journey to eternity. Leukemia 1997;11(12):2175-87.10.1038/sj.leu.24008499447838
  11. 11. Hanada M, Delia D, Aiello A, Stadtmauer E, Reed JC. bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 1993;82(6):1820-8.10.1182/blood.V82.6.1820.1820
  12. 12. Calin GA, Dumitru CD, Shimizu M, et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A 2002;99(24):15524-9.10.1073/pnas.24260679913775012434020
  13. 13. Cimmino A, Calin GA, Fabbri M, et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci U S A 2005;102(39):13944-9.10.1073/pnas.0506654102123657716166262
  14. 14. Nuckel H, Frey UH, Bau M, et al. Association of a novel regulatory polymorphism (-938C>A) in the BCL2 gene promoter with disease progression and survival in chronic lymphocytic leukemia. Blood 2007;109(1):290-7.10.1182/blood-2006-03-00756716960146
  15. 15. Majid A, Tsoulakis O, Walewska R, et al. BCL2 expression in chronic lymphocytic leukemia: lack of association with the BCL2 938A>C promoter single nucleotide polymorphism. Blood 2008;111(2):874-7.10.1182/blood-2007-07-09868117959858
  16. 16. Dohner H, Stilgenbauer S, Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000;343(26):1910-6.10.1056/NEJM20001228343260211136261
  17. 17. Pettitt AR, Sherrington PD, Stewart G, et al. p53 dys-function in B-cell chronic lymphocytic leukemia: inactivation of ATM as an alternative to TP53 mutation. Blood 2001;98(3):814-22.10.1182/blood.V98.3.81411468183
  18. 18. Rossi D, Cerri M, Deambrogi C, et al. The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of Del17p13: implications for overall survival and chemorefractoriness. Clin Cancer Res 2009;15(3):995-1004.10.1158/1078-0432.CCR-08-163019188171
  19. 19. Cuni S, Perez-Aciego P, Perez-Chacon G, et al. A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells. Leukemia 2004;18(8):1391-400.10.1038/sj.leu.240339815175625
  20. 20. Ringshausen I, Schneller F, Bogner C, et al. Constitutively activated phosphatidylinositol-3 kinase (PI-3K) is involved in the defect of apoptosis in BCLL: association with protein kinase Cdelta. Blood 2002;100(10):3741-8.10.1182/blood-2002-02-053912393602
  21. 21. Barragan M, Bellosillo B, Campas C, et al. Involvement of protein kinase C and phosphatidylinositol 3-kinase pathways in the survival of B-cell chronic lymphocytic leukemia cells. Blood 2002;99(8):2969-76.10.1182/blood.V99.8.2969
  22. 22. Hewamana S, Alghazal S, Lin TT, et al. The NF-kappaB subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target. Blood 2008;111(9):4681-9.10.1182/blood-2007-11-12527818227347
  23. 23. Panayiotidis P, Ganeshaguru K, Foroni L, Hoffbrand AV. Expression and function of the FAS antigen in B chronic lymphocytic leukemia and hairy cell leukemia. Leukemia 1995;9(7):1227-32.
  24. 24. Osorio LM, Aguilar-Santelises M, De Santiago A, et al. Increased serum levels of soluble Fas in progressive BCLL. Eur J Haematol 2001;66(5):342-6.10.1034/j.1600-0609.2001.066005342.x11422415
  25. 25. Pepper C, Lin TT, Pratt G, et al. Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers. Blood 2008;112(9):3807-17.10.1182/blood-2008-05-15713118599795
  26. 26. Vogler M, Butterworth M, Majid A, et al. Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia. Blood 2009;113(18):4403-13.10.1182/blood-2008-08-17331019008458
  27. 27. Karan-Djurasevic T, Palibrk V, Zukic B, et al. Expression of Bcl2L12 in chronic lymphocytic leukemia patients: association with clinical and molecular prognostic markers. Med Oncol 2013;30(1):405.10.1007/s12032-012-0405-723292833
  28. 28. Robertson LE, Plunkett W, McConnell K, Keating MJ, McDonnell TJ. Bcl-2 expression in chronic lymphocytic leukemia and its correlation with the induction of apoptosis and clinical outcome. Leukemia 1996;10(3):456-9.
  29. 29. Caligaris-Cappio F, Hamblin TJ. B-cell chronic lymphocytic leukemia: a bird of a different feather. Journal of Clinical Oncology 1999;17:399-408.10.1200/JCO.1999.17.1.39910458259
  30. 30. Faderl S, Keating MJ, Do KA, et al. Expression profile of 11 proteins and their prognostic significance in patients with chronic lymphocytic leukemia (CLL). Leukemia 2002;16(6):1045-52.10.1038/sj.leu.240254012040436
  31. 31. Aviram A, Rabizadeh E, Zimra Y, et al. Expression of bcl-2 and bax in cells isolated from B-chronic lymphocytic leukemia patients at different stages of the disease. Eur J Haematol 2000;64(2):80-4.10.1034/j.1600-0609.2000.90042.x10997327
  32. 32. Saxena A, Viswanathan S, Moshynska O, et al. Mcl-1 and Bcl-2/Bax ratio are associated with treatment response but not with Rai stage in B-cell chronic lymphocytic leukemia. Am J Hematol 2004;75(1):22-33.10.1002/ajh.1045314695629
  33. 33. Packham G, Stevenson FK. Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia. Immunology 2005;114(4):441-9.10.1111/j.1365-2567.2005.02117.x178211815804279
  34. 34. Placzek WJ, Wei J, Kitada S, et al. A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy. Cell Death Dis 2010;1:e40.10.1038/cddis.2010.18303231221364647
  35. 35. Rogalinska M, Franiak-Pietryga I, Blonski JZ, et al. Toward personalized therapy for chronic lymphocytic leukemia: DSC and cDNA microarray assessment of two cases. Cancer Biol Ther 2013;14(1):6-12.10.4161/cbt.22623356605423114648
DOI: https://doi.org/10.1515/sjecr-2015-0024 | Journal eISSN: 2956-2090 | Journal ISSN: 2956-0454
Language: English
Page range: 187 - 191
Submitted on: Dec 25, 2014
|
Accepted on: Feb 20, 2015
|
Published on: Oct 14, 2015
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2015 Ksenija Vucicevic, Vladimir Jakovljevic, Jasmina Sretenovic, Natasa Tosic, Tatjana Kostic, Irena Glumac, Milica Colovic, Natasa Colovic, Sonja Pavlovic, Teodora Karan-Djurasevic, published by University of Kragujevac, Faculty of Medical Sciences
This work is licensed under the Creative Commons Attribution 4.0 License.