Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Peter Peciar; Maroš Eckert; Roman Fekete; Viliam Hrnčiar

doi:10.1515/scjme-2016-0012

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Analysis of Pharmaceutical Excipient MCC Avicel PH102 Using Compaction Equations

Strojnícky časopis - Journal of Mechanical Engineering

Volume 66 (2016): Issue 1 (July 2016)

By: Peter Peciar, Maroš Eckert, Roman Fekete and Viliam Hrnčiar

Open Access

|Aug 2016

Abstract

This paper focuses on the characterization of the tabletting process and analysis one of the most common pharmaceutical excipients MCC Avicel PH102 by Heckel, Kawakita, Cooper-Eaton and Adams compaction equations. Experimental material was determined by measuring its parameters as particle size distribution, angle of wall friction and flow properties and for more detailed characteristics of the material particles, microscopy images of the powder before and after compressing were created.

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Articles in this issue

DOI: https://doi.org/10.1515/scjme-2016-0012 | Journal eISSN: 2450-5471 | Journal ISSN: 0039-2472

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Language: English

Page range: 65 - 82

Published on: Aug 19, 2016

Published by: Slovak University of Technology in Bratislava

In partnership with: Paradigm Publishing Services

Publication frequency: 2 issues per year

Keywords:

Compaction equation,

tabletting,

angle of internal friction,

angle of wall friction

Related subjects:

Engineering,

Mechanical engineering,

Fundamentals of mechanical engineering,

Mechanics

© 2016 Peter Peciar, Maroš Eckert, Roman Fekete, Viliam Hrnčiar, published by Slovak University of Technology in Bratislava
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 66 (2016): Issue 1 (July 2016)