Two (Sulfone-Amidosulphonyl)-Amides Derived from N-(P-Amidobenzoyl)-L-Glutamine; Optimized Synthesis and Toxicity Study
Abstract
Two derivatives of glutamine were synthesized and the most convenient physical conditions for obtaining reactions were established in factorial experiments with temperature and time of reactions considered as relevant variables. A quantum-mechanical characterization for the new compounds was performed by using HyperChem 8.0.6 Programs and their physical and chemical properties were theoretically estimated. The toxicity of two new compounds was experimentally determined.
DOI: https://doi.org/10.1515/kbo-2016-0105 | Journal eISSN: 2451-3113
Language: English
Page range: 609 - 615
Published on: Jul 27, 2016
Published by: Nicolae Balcescu Land Forces Academy
In partnership with: Paradigm Publishing Services
Publication frequency: 3 issues per year
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© 2016 Corina Cheptea, Andreea Celia Benchea, Marius Gaina, Dana Ortansa Dorohoi, Valeriu Sunel, published by Nicolae Balcescu Land Forces Academy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.