References
- Chaudhury A, Duvoor C, Reddy Dendi VS, Kraleti S, Chada A, Ravilla R, et al. Clinical review of antidiabetic drugs: Implications for type 2 diabetes mellitus management. Front Endocrinol. 2017;8:6. 10.3389/fendo.2017.00006.
- Zaccardi F, Webb DR, Yates T, Davies MJ. Pathophysiology of type 1 and type 2 diabetes mellitus a 90-year perspective. Postgrad Med J. 2016;92(1084):63–9.
- Ozougwu J, Obimba K, Belonwu CD, Unakalamba CB. The pathogenesis and pathophysiology of type 1 and type 2 diabetes mellitus. J Physiol Pathophysiol. 2013;4(4):46–57.
- Tangvarasittichai S. Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus. World J Diabetes. 2015;6(3):456–80.
- Filippatos G, Anker SD, Bohm M, Gheorghiade M, Kober L, Krum H, et al. A randomized controlled study of finerenone vs. eplerenone in patients with worsening chronic heart failure and diabetes mellitus and/or chronic kidney disease. Eur Heart J. 2016;37(27):2105–14.
- Nogueira-Machado JA, Chaves MM. From hyperglycemia to AGE-RAGE interaction on the cell surface a dangerous metabolic route for diabetic patients. Expert Opin Ther Targets. 2008;12(7):871–82.
- Shen Y, Cheng L, Xu M, Wang W, Wan Z, Xiong H, et al. SGLT2 inhibitor empagliflozin downregulates miRNA-34a-5p and targets GREM2 to inactivate hepatic stellate cells and ameliorate non-alcoholic fatty liver disease-associated fibrosis. Metabolism. 2023;146:155657. 10.1016/j.metabol.2023.155657.
- Zeng Y, Wei X, Ma SQ, Wang QG, Qi Z, Duan ZC, et al. Preclinical evidence of reno-protective effect of quercetin on acute kidney injury: a meta-analysis of animal studies. Front Pharmacol. 2023;14:1310023. 10.3389/fphar.2023.1310023.
- Yi-Wen Z, Mei-Hua B, Xiao Ya L, Yu C, Jing Y, Hong Hao Z. Effects of oridonin on hepatic cytochrome P450 expression and activities in PXR-humanized mice. Biol Pharm Bull. 2018;41(5):707–12.
- Cheng X, Huang J, Li H, Zhao D, Liu Z, Zhu L, et al. Quercetin A promising therapy for diabetic encephalopathy through inhibition of hippocampal ferroptosis. Phytomedicine. 2024;126:112285. org/10.1016/j.phymed.2023.154887.
- Li W, Liu X, Liu Z, Xing Q, Liu R, Wu Q, et al. The signaling pathways of selected traditional Chinese medicine prescriptions and their metabolites in the treatment of diabetic cardiomyopathy: a review. Front Pharmacol. 2024;15:416403. 10.3389/fphar.2024.1416403.
- Suthar M, Rathore GS, Pareek A. Antioxidant and antidiabetic activity of Helicteres isora (L.) fruits. Indian J Pharm Sci. 2009;71(6):695.
- Bilal H, Khan MA, Shah SWA, Ghias M, Hussain H, Ali HR, et al. Pre-clinical safety profile and behavioral effects of helicteres isora linn in an animal model. 2023;37(11):6231–45.
- Siano F, Picariello G, Castaldo D, Cautela D, Caruso T, Vasca E. Monitoring antioxidants by coulometry: Quantitative assessment of the strikingly high antioxidant capacity of bergamot (Citrus bergamia R.) by-products. Talanta. 2023;251:123765. 10.1016/j.talanta.2022.123765.
- Ali A, Khalil AA, Khuda F, Nazir N, Ullah R, Bari A, et al. Phytochemical and biological screening of leaf, bark and fruit extracts from Ilex dipyrena wall. Life. 2021;11(8):837.
- Shah SWA, Ghias M, Shoaib M, Ali N, Shah I, Umar MN, et al. Antidiabetic potential of flavonoids from Artemisia macrocephalla Jaquem in streptozotocin-induced diabetic rats: Pharmacological and biochemical approach. 2019;32(6):2865–71.
- Bischoff M, Mukai SK. Ramaiah, Liver toxicity, in Veterinary toxicology. Amsterdam: Elsevier; 2018. p. 239–57.
- Pizzorno J. The kidney dysfunction epidemic, part 1: causes. Integr Med. 2015;14(6):8–13.
- Jamal A. Embracing Nature’s therapeutic potential herbal medicine. Int J Multidiscip Sci Arts. 2023;2(1):117–26.
- Akbari B, Yazdi N, Bahmaie M, Mahdavi Abhari F. The role of plant‐derived natural antioxidants in reduction of oxidative stress. BioFactors. 2022;48(3):611–33.
- Dosoky NS, Setzer WN. Chemical composition and biological activities of essential oils of Curcuma species. Nutrients. 2018;10(9):10091196. 10.3390/nu10091196.
- Venkatesh S, Madhava Reddy B, Dayanand Reddy G, Mullangi R, Lakshman M. Antihyperglycemic and hypolipidemic effects of Helicteres isora roots in alloxan-induced diabetic rats: a possible mechanism of action. J Nat Med. 2010;64:295–304.
- Khanum R, Thevanayagam H. Lipid peroxidation: Its effects on the formulation and use of pharmaceutical emulsions. Asian J Pharm Sci. 2017;12(5):401–11.
- Othman RA, Moghadasian MH. Beyond cholesterol-lowering effects of plant sterols: clinical and experimental evidence of anti-inflammatory properties. Nutr Rev. 2011;69(7):371–82.
- Hauser AS, Attwood MM, RaskAndersen M, Schioth HB, Gloriam DE. Trends in GPCR drug discovery: new agents, targets and indications. 2017;16(12):829–42.
- Khan MS, Razzaq A. Ethnobotanical indices based ethnoveterinary plant profile of Jabban hills. Malak Hindu Kush range Pak. 2018;50(5):1899–905.
- Belhattab R, Amor L, Barroso JG, Pedro LG. Essential oil from Artemisia herba-alba Asso grown wild in Algeria: Variability assessment and comparison with an updated literature survey. 2014;7(2):243–51.
- Gupta RN, Pareek A, Suthar M, Rathore GS, Basniwal PK, Jain D. Study of glucose uptake activity of Helicteres isora Linn. fruits in L-6 cell lines. Int J Diabetes Dev Ctries. 2009;29(4):170–3.
- Mworia JK, Kibiti CM, Ngugi MP, Ngeranwa JN. Antipyretic potential of dichloromethane leaf extract of Eucalyptus globulus (Labill) and Senna didymobotrya (Fresenius) in rats models. Heliyon. 2019;5(12):e02924. 10.1016/j.heliyon.2019.e02924.
- Kumar N, Singh AK. Plant profile, phytochemistry and pharmacology of Avartani (Helicteres isora Linn.) A review. Asian Pac J Trop Biomed. 2014;4:22–6.