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MMP-2 Plays an Important Role During the Early Acute Developmental Phase of Oligofructose-Induced Equine Laminitis Cover

MMP-2 Plays an Important Role During the Early Acute Developmental Phase of Oligofructose-Induced Equine Laminitis

Journal of Veterinary Research
Volume 59 (2015): Issue 1 (March 2015)
By: ,  ,  ,  ,  ,  ,  ,   and    
Open Access
|Apr 2015
References

References

  1. 1. Bailey S.R., Adair H.S., Reinemeyer C.R., Morgan S.J., Brooks A.C., Longhofer S.L., Elliott J.: Plasma concentrations of endotoxin and platelet activation in the developmental stage of oligofructose-induced laminitis. Vet Immunol Immunopathol 2009, 129, 167–173.
    Open DOISearch in Google Scholar
  2. 2. Belknap J.K.: Black walnut extract: an inflammatory model. Vet Clin North Am Equine Pract 2010, 26, 95–101.
    Open DOISearch in Google Scholar
  3. 3. Brooks A.C., Menzies-Gow N.J., Wheeler-Jones C., Bailey S.R., Cunningham F.M., Elliott J.: Endotoxin-induced activation of equine platelets: evidence for direct activation of p38 MAPK pathways and vasoactive mediator production. Inflamm Res 2007, 56, 154–161.
    Open DOISearch in Google Scholar
  4. 4. Collins S.N., van Eps A.W., Pollitt C.C., Kuwano A.: The lamellar wedge. Vet Clin North Am Equine Pract 2010, 26, 179–195.
    Open DOISearch in Google Scholar
  5. 5. Antonella D., Rosa D., Michele Q., Vittorio M., Porzia C., Angelo P., Vito M.G., Cosimo D.G., Gennaro G.C., Eufemia S., Rosanna M., Antonia B., Vito F.: Clinical and prognostic role of circulating MMP-2 and its inhibitor TIMP-2 in HCC patients prior to and after trans-hepatic arterial chemo-embolization. Clin Biochem 2013, 47, 184–190.
    Open DOISearch in Google Scholar
  6. 6. De Laat M.A., Clement C.K., McGowan C.M., Sillence M.N., Pollitt C.C., Lacombe V.A.: Toll-like receptor and pro-inflammatory cytokine expression during prolonged hyperinsulinaemia in horses: Implications for laminitis. Vet Immunol Immunopathol 2014, 157, 78–86.
    Open DOISearch in Google Scholar
  7. 7. De Laat M.A., Kyaw-Tanner M.T., Nourian A.R., McGowan C.M., Sillence M.N., Pollitt C.C.: The developmental and acute phases of insulin-induced laminitis involve minimal metalloproteinase activity. Vet Immunol Immunopathol 2011, 140, 275–281.
    Open DOISearch in Google Scholar
  8. 8. De Laat M.A., Patterson-Kane J.C., Pollitt C.C., Sillence M.N., McGowan C.M.: Histological and morphometric lesions in the pre-clinical, developmental phase of insulin-induced laminitis in Standardbred horses. Vet J 2013, 195, 305–312.
    Open DOISearch in Google Scholar
  9. 9. Donnini S., Morbidelli L., Taraboletti G., Ziche M.: ERK1-2 and p38 MAPK regulate MMP/TIMP balance and function in response to thrombospondin-1 fragments in the microvascular endothelium. Life Sci 2004, 74, 2975–2985.
    Open DOISearch in Google Scholar
  10. 10. Dugdale A.H., Grove-White D., Curtis G.C., Harris P.A., Argo C.M.: Body condition scoring as a predictor of body fat in horses and ponies. Vet J 2012, 194, 173–178.
    Open DOISearch in Google Scholar
  11. 11. Eades S.C.: Overview of current laminitis research. Vet Clin North Am Equine Pract 2010, 26, 51–63.
    Open DOISearch in Google Scholar
  12. 12. Eps A.V., Pollitt C.C.: Equine laminitis induced with oligofructose. Equine Vet J 2006, 38, 203–208.
    Open DOISearch in Google Scholar
  13. 13. Howard E.W., Crider B.J., Updike D.L., Bullen E.C., Parks E.E., Haaksma C.J., Sherry D.M., Tomasek J.J.: MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype. Exp Cell Res 2012, 318, 1542-1553.
    Open DOISearch in Google Scholar
  14. 14. Loftus J.P., Johnson P.J., Belknap J.K, Pettigrew A, Black S.J.: Leukocyte-derived and endogenous matrix metalloproteinases in the lamellae of horses with naturally acquired and experimentally induced laminitis. Vet Immunol Immunopathol 2009, 129, 221-230.
    Open DOISearch in Google Scholar
  15. 15. Longland A.C, Byrd B.M.: Pasture nonstructural carbohydrates and equine laminitis. J Nutr 2006, 136, 2099-2102.
    Open DOISearch in Google Scholar
  16. 16. Menzies-Gow N.J., Bailey S.R, Katz L.M., Marr CM., Elliott J.: Endotoxin-induced digital vasoconstriction in horses: associated changes in plasma concentrations of vasoconstrictor mediators. Equine Vet J 2004, 36, 273-278.
    Open DOISearch in Google Scholar
  17. 17. Moore J.N., Garner H.E., Berg J.N., Sprouse R.F.: Intracecal endotoxin and lactate during the onset of equine laminitis: a preliminary report. Am J Vet Res 1979, 40, 722-723.
    Search in Google Scholar
  18. 18. Morris D.D.: Endotoxemia in horses: a review of cellular and humoral mediators involved in its pathogenesis. J Vet Intern Med 1991, 5, 167-181.
    Open DOISearch in Google Scholar
  19. 19. Pollitt CC: The anatomy and physiology of the suspensory apparatus of the distal phalanx. Vet Clin North Am Equine Pract 2010, 26, 29-49.
    Open DOISearch in Google Scholar
  20. 20. Pollitt CC, Visser M.B.: Carbohydrate alimentary overload laminitis. Vet Clin North Am Equine Pract 2010, 26, 65-78.
    Open DOISearch in Google Scholar
  21. 21. Pons M, Cousins S.W., Alcazar O, Striker G.E, Marin-Castaño M.E.: Angiotensin II-Induced MMP-2 activity and MMP-14 and Basigin protein expression are mediatedthe angiotensin II receptor type 1-mitogen-activated protein kinase 1 pathway in retinal pigment epithelium: implications for age-related macular degeneration. Am J Pathol 2011, 178, 2665-2681.
    Open DOISearch in Google Scholar
  22. 22. Radziwon-Balicka A, Ramer C, Moncada de la Rosa C., Zielnik-Drabik B, Jurasz P.: Angiostatin inhibits endothelial MMP-2 and MMP-14 expression: a hypoxia specific mechanism of action. Vascul Pharmacol 2013, 58, 280-291.
    Open DOISearch in Google Scholar
  23. 23. Stewart AJ, Pettigrew A, Cochran A.M, Belknap J.K.: Indices of inflammation in the lung and liver in the early stages of the black walnut extract model of equine laminitis. Vet Immunol Immunopathol 2009, 129, 254-260.
    Open DOISearch in Google Scholar
  24. 24. Tadros E.M, Frank N, Horohov D.W.: Inflammatory cytokine gene expression in blood during the development of oligofructose-induced laminitis in horses. J Equine Vet Sci 2013, 33, 802-808.
    Open DOISearch in Google Scholar
  25. 25. Taylor D, Hood D.M, Wagner I.P.: Short-term effect of therapeutic shoeing on severity of lameness in horses with chronic laminitis. Am J Vet Res 2002, 63, 1629-1633.
    Open DOISearch in Google Scholar
  26. 26. Toth F, Frank N, Chameroy K.A, Boston R.C.: Effects of endotoxaemia and carbohydrate overload on glucose and insulin dynamics and the development of laminitis in horses. Equine Vet J 2009, 41, 852-858.
    Open DOISearch in Google Scholar
  27. 27. Visser M.B, Pollitt CC: Lamellar leukocyte infiltration and involvement of IL-6 during oligofructose-induced equine laminitis development. Vet Immunol Immunopathol 2011, 144, 120-128.
    Open DOISearch in Google Scholar
  28. 28. Wang L, Pawlak E.A, Johnson P.J, Belknap J.K, Alfandari D, Black S.J.: Expression and activity of metalloproteinases in the digital laminae of horses with starch gruel-induced laminitis. J Equine Vet Sci 2011, 31, 566.
    Open DOISearch in Google Scholar
  29. 29. Wilkinson J.M, Davidson R.K, Swingler T.E, Jones E.R, Corps A.N, Johnston P, Riley G.P, Chojnowski AJ, Clark I.M.: MMP-14 and MMP-2 are key metalloproteases in Dupuytren's disease fibroblast-mediated contraction. Biochim Biophys Acta 2012, 1822, 897-905.
    Open DOISearch in Google Scholar
  30. 30. Yang J, Wang G, Gao C, Shao G, Kang N.: Effects of hyperbaric oxygen on MMP-2 and MMP-9 expression and spinal cord edema after spinal cord injury. Life Sci 2013, 93, 1033-1038.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.1515/bvip-2015-0022 | Journal eISSN: 2450-8608 (formerly 2300-3235)
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Language: English
Page range: 149 - 153
Submitted on: Jul 18, 2014
Accepted on: Jan 14, 2015
Published on: Apr 1, 2015
Published by: National Veterinary Research Institute in Pulawy
In partnership with: Paradigm Publishing Services
Keywords:
horses,
laminitis,
oligofructose,
MMP-2,
P38 MAPK
Related subjects:
Life sciences,
Molecular biology,
Microbiology and virology,
Life sciences, other,
Medicine,
Veterinary medicine

© 2015 Xinran Li, Renli Jiang, Guanying Wang, Yue Li, Xiaojing Fan, Xu Liu, Jinglu Wang, Jialiang Pan, Li Gao, published by National Veterinary Research Institute in Pulawy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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