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The therapeutic agents that target ATP-sensitive potassium channels Cover

The therapeutic agents that target ATP-sensitive potassium channels

Acta Pharmaceutica
Volume 66 (2016): Issue 1 (March 2016)
By:   
Open Access
|Mar 2016
References

References

  1. 1. B. Hille,Sinauer Associates, Sunderland 2001, p. 814.
    Search in Google Scholar
  2. 2. S. Choe, Potassium channel structures,.(2002) 115–121; DOI: 10.1038/nrn727.
    Open DOISearch in Google Scholar
  3. 3. C. C. Shieh, M. Coghlan, J. P. Sullivan and M. Gopalakrishnan, Potassium channels: molecular defects, diseases, and therapeutic opportunities,.(2000) 557–594.
    Search in Google Scholar
  4. 4. C. A. Doupnik, N. Davidson and H. A. Lester, The inward rectifier potassium channel family,.(1995) 268–277; DOI: 10.1016/0959-4388(95)80038-7.
    Open DOISearch in Google Scholar
  5. 5. C. G. Nichols and A. N. Lopatin, Inward rectifier potassium channels,.(1997) 171–191; DOI: 10.1146/annurev.physiol.59.1.171.
    Open DOISearch in Google Scholar
  6. 6. D. Bichet, F. A. Haass and L. Y. Jan, Merging functional studies with structures of inward-rectifier K(+) channels,.(2003) 957–967; DOI: 10.1038/nrn1244.
    Open DOISearch in Google Scholar
  7. 7. D. E. Logothetis, D. Lupyan and A. Rosenhouse-Dantsker, Diverse Kir modulators act in close proximity to residues implicated in phosphoinositide binding,.(2007) 953–965; DOI: 10.1113/jphysiol.2007.133157.
    Open DOISearch in Google Scholar
  8. 8. L. H. Xie, S. A. John, B. Ribalet and J. N. Weiss, Activation of inwardly rectifying potassium (Kir) channels by phosphatidylinosital-4,5-bisphosphate (PIP2): interaction with other regulatory ligands,.(2007) 320–335; DOI: 10.1016/j.pbiomolbio.2006.04.001.
    Open DOISearch in Google Scholar
  9. 9. A. Noma, ATP-regulated Kchannels in cardiac muscle,(1983) 147–148; DOI: 10.1038/305147a0.
    Open DOISearch in Google Scholar
  10. 10. D. L. Cook and C. N. Hales, Intracellular ATP directly blocks Kchannels in pancreatic B-cells,(1984) 271–273; DOI: 10.1038/311271a0.
    Open DOISearch in Google Scholar
  11. 11. A. E. Spruce, N. B. Standen and P. R. Stanfield, Voltage-dependent ATP-sensitive potassium channels of skeletal muscle membrane,(1985) 736–738; DOI: 10.1038/316736a0.
    Open DOISearch in Google Scholar
  12. 12. S. J. Ashcroft and F. M. Ashcroft, Properties and functions of ATP-sensitive K-channels,.(1990) 197–214; DOI 10.1016/0898-6568(90)90048-F.
    Open DOISearch in Google Scholar
  13. 13. N. B. Standen, J. M. Quayle, N. W. Davies, J. E. Brayden, Y. Huang and M. T. Nelson, Hyperpolarizing vasodilators activate ATP-sensitive Kchannels in arterial smooth muscle,(1989) 177–180; DOI: 10.1126/science.2501869.
    Open DOISearch in Google Scholar
  14. 14. L. Aguilar-Bryan and J. Bryan, Molecular biology of adenosine triphosphate-sensitive potassium channels,.(1999) 101–135; DOI: 10.1210/edrv.20.2.0361.
    Open DOISearch in Google Scholar
  15. 15. G. E. Billman, The cardiac sarcolemmal ATP-sensitive potassium channel as a novel target for anti-arrhythmic therapy,.(2008) 54–70; DOI: 10.1016/j.pharmthera.2008.07.004.
    Open DOISearch in Google Scholar
  16. 16. S. Isomoto and Y. Kurachi, [Molecular and biophysical aspects of potassium channels],. ()(1996) 660–666.
    Search in Google Scholar
  17. 17. J. Bryan and L. Aguilar-Bryan, Sulfonylurea receptors: ABC transporters that regulate ATP-sensitive K(+) channels,(1999) 285–303; DOI: 10.1016/S0005-2736(99)00164-9.
    Open DOISearch in Google Scholar
  18. 18. N. Inagaki and S. Seino, ATP-sensitive potassium channels: structures, functions, and pathophysiology,.(1998) 397–412; DOI: 10.2170/jjphysiol.48.397.
    Open DOISearch in Google Scholar
  19. 19. M. Matsuo, K. Tanabe, N. Kioka, T. Amachi and K. Ueda, Different binding properties and affinities for ATP and ADP among sulfonylurea receptor subtypes, SUR1, SUR2A, and SUR2B,.(2000) 28757–28763; DOI: 10.1074/jbc.M004818200.
    Open DOISearch in Google Scholar
  20. 20. M. Dean, A. Rzhetsky and R. Allikmets, The human ATP-binding cassette (ABC) transporter superfamily,.(2001) 1156–1166; DOI: 10.1101/gr.184901.
    Open DOISearch in Google Scholar
  21. 21. L. Aguilar-Bryan, J. P. Clement IV, G. Gonzalez, K. Kunjilwar, A. Babenko and J. Bryan, Toward understanding the assembly and structure of KATP channels,.(1998) 227–245.
    Open DOISearch in Google Scholar
  22. 22. B. G. Gabrielsson, A. C. Karlsson, M. Lonn, L. E. Olofsson, J. M. Johansson, J. S. Torgerson, L. Sjostrom, B. Carlsson, S. Eden and L. M. Carlsson, Molecular characterization of a local sulfonylurea system in human adipose tissue,.(2004) 65–71; DOI: 10.1023/B:MCBI.0000012837.11847.c8.
    Open DOISearch in Google Scholar
  23. 23. C. F. Higgins, ABC transporters: physiology, structure and mechanism-an overview,.(2001) 205–210.
    Search in Google Scholar
  24. 24. J. E. Walker, M. Saraste, M. J. Runswick and N. J. Gay, Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold,.(1982) 945–951.
    Open DOISearch in Google Scholar
  25. 25. R. Mannhold, KATP channel openers: structure-activity relationships and therapeutic potential,.(2004) 213–266; DOI: 10.1002/med.10060.
    Open DOISearch in Google Scholar
  26. 26. J. P. Clement IV, K. Kunjilwar, G. Gonzalez, M. Schwanstecher, U. Panten, L. Aguilar-Bryan and J. Bryan, Association and stoichiometry of K(ATP) channel subunits,(1997) 827–838; DOI: 10.1016/S0896-6273(00)80321-9.
    Open DOISearch in Google Scholar
  27. 27. D. Enkvetchakul, G. Loussouarn, E. Makhina and C. G. Nichols, ATP interaction with the open state of the K(ATP) channel,.(2001) 719–728; DOI: 10.1016/S0006-3495(01)76051-1.
    Open DOISearch in Google Scholar
  28. 28. M. A. Burke, R. K. Mutharasan and H. Ardehali, The sulfonylurea receptor, an atypical ATP-bin ding cassette protein, and its regulation of the KATP channel,.(2008) 164–176; DOI: 10.1161/CIRCRESAHA.107.165324.
    Open DOISearch in Google Scholar
  29. 29. F. M. Ashcroft and F. M. Gribble, Correlating structure and function in ATP-sensitive Kchannels,.(1998) 288–294; DOI: 10.1016/S0166-2236(98)01225-9.
    Open DOISearch in Google Scholar
  30. 30. S. Seino, Physiology and pathophysiology of K(ATP) channels in the pancreas and cardiovascular system: a review,.(2003) 2–5; DOI: 10.1016/S1056-8727(02)00274-X.
    Open DOISearch in Google Scholar
  31. 31. S. Sattiraju, S. Reyes, G. C. Kane and A. Terzic, K(ATP) channel pharmacogenomics: from bench to bedside,.(2008) 354–357; DOI: 10.1038/sj.clpt.6100378.
    Open DOISearch in Google Scholar
  32. 32. K. Hussain and K. E. Cosgrove, From congenital hyperinsulinism to diabetes mellitus: the role of pancreatic beta-cell KATP channels,(2005) 103–113; DOI: 10.1111/j.1399-543X.2005.00109.x.
    Open DOISearch in Google Scholar
  33. 33. N. Deutsch, T. S. Klitzner, S. T. Lamp and J. N. Weiss, Activation of cardiac ATP-sensitive Kcurrent during hypoxia: correlation with tissue ATP levels,.(1991) H671-6.
    Search in Google Scholar
  34. 34. Y. G. Kwak, S. K. Park, U. H. Kim, M. K. Han, J. S. Eun, K. P. Cho and S. W. Chae, Intracellular ADP-ribose inhibits ATP-sensitive K+ channels in rat ventricular myocytes,.(1996) C464-8.
    Open DOISearch in Google Scholar
  35. 35. H. Yokoshiki, M. Sunagawa, T. Seki and N. Sperelakis, ATP-sensitive Kchannels in pancreatic, cardiac, and vascular smooth muscle cells,.(1998) C25–C37.
    Open DOISearch in Google Scholar
  36. 36. J. E. Brayden, Functional roles of KATP channels in vascular smooth muscle,.(2002) 312–316; DOI: 10.1046/j.1440-1681.2002.03650.x.
    Open DOISearch in Google Scholar
  37. 37. M. Yamada, S. Isomoto, S. Matsumoto, C. Kondo, T. Shindo, Y. Horio and Y. Kurachi, Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive Kchannel,.(1997) 715–20; DOI: 10.1113/jphysiol.1997.sp021963.
    Open DOISearch in Google Scholar
  38. 38. J. Roper and F. M. Ashcroft, Metabolic inhibition and low internal ATP activate K-ATP channels in rat dopaminergic substantia nigra neurones,.(1995) 44–54; DOI: 10.1007/BF00373838.
    Open DOISearch in Google Scholar
  39. 39. I. M. Stanford and M. G. Lacey, Electrophysiological investigation of adenosine trisphosphate-sensitive potassium channels in the rat substantia nigra pars reticulata,(1996) 499–509; DOI: 10.1016/0306-4522(96)00151-0.
    Open DOISearch in Google Scholar
  40. 40. M. L. Ashford, P. R. Boden and J. M. Treherne, Tolbutamide excites rat glucoreceptive ventromedial hypothalamic neurones by indirect inhibition of ATP-Kchannels,.(1990) 531–540; DOI: 10.1111/j.1476-5381.1990.tb14116.x.
    Open DOISearch in Google Scholar
  41. 41. M. Chien, I. Morozova, S. Shi, H. Sheng, J. Chen, S. M. Gomez, G. Asamani, K. Hill, J. Nuara, M. Feder, J. Rineer, J. J. Greenberg, V. Steshenko, S. H. Park, B. Zhao, E. Teplitskaya, J. R. Edwards, S. Pampou, A. Georghiou, I. C. Chou, W. Iannuccilli, M. E. Ulz, D. H. Kim, A. Geringer-Sameth, C. Goldsberry, P. Morozov, S. G. Fischer, G. Segal, X. Qu, A. Rzhetsky, P. Zhang, E. Cayanis, P. J. De Jong, J. Ju, S. Kalachikov, H. A. Shuman and J. J. Russo, The genomic sequence of the accidental pathogen,(2004) 1966–1968; DOI: 10.1126/science.1099776.
    Open DOISearch in Google Scholar
  42. 42. K. Yamada and N. Inagaki, ATP-sensitive K(+) channels in the brain: sensors of hypoxic conditions,.(2002) 127–30.
    Search in Google Scholar
  43. 43. N. W. Davies, Modulation of ATP-sensitive Kchannels in skeletal muscle by intracellular protons,(1990) 375–377; DOI: 10.1038/343375a0.
    Open DOISearch in Google Scholar
  44. 44. J. J. Nielsen, M. Kristensen, Y. Hellsten, J. Bangsbo and C. Juel, Localization and function of ATP-sensitive potassium channels in human skeletal muscle,.(2003) R558-R63; DOI: 10.1152/ajpregu.00303.2002.
    Open DOISearch in Google Scholar
  45. 45. S. M. Gopalakrishnan, C. Chen and M. F. Lokhandwala, Identification of alpha 1-adrenoceptor subtypes in rat renal proximal tubules,.(1993) 469–472; DOI: 10.1016/0014-2999(93)90036-H.
    Open DOISearch in Google Scholar
  46. 46. A. P. Babenko, L. Aguilar-Bryan and J. Bryan, A view of sur/KIR6.X, KATP channels,.(1998) 667–687; DOI: 10.1146/annurev.physiol.60.1.667.
    Open DOISearch in Google Scholar
  47. 47. S. Seino, ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies,.(1999) 337–362; DOI: 10.1146/annurev.physiol.61.1.337.
    Open DOISearch in Google Scholar
  48. 48. N. Inagaki, T. Gonoi, J. P. Clement IV, N. Namba, J. Inazawa, G. Gonzalez, L. Aguilar-Bryan, S. Seino and J. Bryan, Reconstitution of: an inward rectifier subunit plus the sulfonylurea receptor,(1995) 1166–1170; DOI: 10.1126/science.270.5239.1166.
    Open DOISearch in Google Scholar
  49. 49. S. Isomoto, C. Kondo, M. Yamada, S. Matsumoto, O. Higashiguchi, Y. Horio, Y. Matsuzawa and Y. Kurachi, A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive Kchannel,.(1996) 24321–24324; DOI: 10.1074/jbc.271.40.24321.
    Open DOISearch in Google Scholar
  50. 50. P. Proks, F. Reimann, N. Green, F. Gribble and F. Ashcroft, Sulfonylurea stimulation of insulin secretion,(2002) S368–S376; DOI: 10.2337/diabetes.51.2007.S368.
    Open DOISearch in Google Scholar
  51. 51. F. M. Gribble and F. Reimann, Pharmacological modulation of K(ATP) channels,.(2002) 333–339; DOI: 10.1042/bst0300333.
    Open DOISearch in Google Scholar
  52. 52. T. Hamaguchi, T. Hirose, H. Asakawa, Y. Itoh, K. Kamado, K. Tokunaga, K. Tomita, H. Masuda, N. Watanabe and M. Namba, Efficacy of glimepiride in type 2 diabetic patients treated with glibenclamide,.(2004) S129–S132; DOI: 10.1016/j.diabres.2003.12.012.
    Open DOISearch in Google Scholar
  53. 53. N. C. Sturgess, M. L. Ashford, D. L. Cook and C. N. Hales, The sulphonylurea receptor may be an ATP-sensitive potassium channel,(1985) 474–475; DOI: 10.1016/S0140-6736(85)90403-9.
    Open DOISearch in Google Scholar
  54. 54. F. M. Gribble, S. J. Tucker and F. M. Ashcroft, The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive Kchannel currents expressed in Xenopus oocytes: a reinterpretation,.(1997) 35–45; DOI: 10.1111/j.1469-7793.1997.00035.x.
    Open DOISearch in Google Scholar
  55. 55. F. M. Gribble and F. M. Ashcroft, Differential sensitivity of beta-cell and extrapancreatic K(ATP) channels to gliclazide,(1999) 845–848; DOI: 10.1007/s001250051236.
    Open DOISearch in Google Scholar
  56. 56. F. Reimann, P. Proks and F. M. Ashcroft, Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel,.(2001) 1542–1548; DOI: 10.1038/sj.bjp.0703962.
    Open DOISearch in Google Scholar
  57. 57. Y. Sunaga, T. Gonoi, T. Shibasaki, K. Ichikawa, H. Kusama, H. Yano and S. Seino, The effects of mitiglinide (KAD-1229), a new anti-diabetic drug, on ATP-sensitive Kchannels and insulin secretion: comparison with the sulfonylureas and nateglinide,.(2001) 119–125; DOI: 10.1016/S0014-2999(01)01412-1.
    Open DOISearch in Google Scholar
  58. 58. F. M. Ashcroft and F. M. Gribble, Tissue-specific effects of sulfonylureas: lessons from studies of cloned K(ATP) channels,.(2000) 192–196; DOI: 10.1016/S1056-8727(00)00081-7.
    Open DOISearch in Google Scholar
  59. 59. S. Hu, S. Wang and B. E. Dunning, Tissue selectivity of antidiabetic agent nateglinide: study on cardiovascular and beta-cell K(ATP) channels,.(1999) 1372–1379.
    Search in Google Scholar
  60. 60. A. Melander, Kinetics-effect relations of insulin-releasing drugs in patients with type 2 diabetes: brief overview,(2004) S151–S155; DOI: 10.2337/diabetes.53.suppl_3.S151.
    Open DOISearch in Google Scholar
  61. 61. R. I. Shorr, W. A. Ray, J. R. Daugherty and M. R. Griffin, Individual sulfonylureas and serious hypoglycemia in older people,.(1996) 751–755; DOI: 10.1111/j.1532-5415.1996.tb03729.x.
    Open DOISearch in Google Scholar
  62. 62. A. Jonsson, T. Rydberg, G. Ekberg, B. Hallengren and A. Melander, Slow elimination of glyburide in NIDDM subjects,(1994) 142–145; DOI: 10.2337/diacare.17.2.142.
    Open DOISearch in Google Scholar
  63. 63. A. Holstein, A. Plaschke and E. H. Egberts, Lower incidence of severe hypoglycaemia in patients with type 2 diabetes treated with glimepiride versus glibenclamide,.(2001) 467–473; DOI: 10.1002/dmrr.235.
    Open DOISearch in Google Scholar
  64. 64. A. Basit, M. Riaz and A. Fawwad, Glimepiride: evidence-based facts, trends, and observations,.(2012) 463–472; DOI: 10.2147/HIV.S33194.
    Search in Google Scholar
  65. 65. J. A. Hirst, A. J. Farmer, A. Dyar, T. W. Lung and R. J. Stevens, Estimating the effect of sulfonylurea on HbA1c in diabetes: a systematic review and meta-analysis,(2013) 973–984; DOI: 10.1007/s00125-013-2856-6.
    Open DOISearch in Google Scholar
  66. 66. K. Kaku, Y. Inoue and T. Kaneko, Extrapancreatic effects of sulfonylurea drugs,.(1995) S105–S108; DOI: 10.1016/0168-8227(95)01078-R.
    Open DOISearch in Google Scholar
  67. 67. A. Terzic, A. Jahangir and Y. Kurachi, Cardiac ATP-sensitive Kchannels: regulation by intracellular nucleotides and Kchannel-opening drugs,.(1995) C525–C545.
    Open DOISearch in Google Scholar
  68. 68. J. P. Arena and R. S. Kass, Activation of ATP-sensitive K channels in heart cells by pinacidil: dependence on ATP,.(1989) H2092–2096.
    Search in Google Scholar
  69. 69. G. Edwards, T. Ibbotson and A. H. Weston, Levcromakalim may induce a voltage-independent K-current in rat portal veins by modifying the gating properties of the delayed rectifier,.(1993) 1037–1048; DOI: 10.1111/j.1476-5381.1993.tb13918.x.
    Open DOISearch in Google Scholar
  70. 70. M. Schwanstecher, C. Sieverding, H. Dorschner, I. Gross, L. Aguilar-Bryan, C. Schwanstecher and J. Bryan, Potassium channel openers require ATP to bind to and act through sulfonylurea receptors,.(1998) 5529–5535; DOI: 10.1093/emboj/17.19.5529.
    Open DOISearch in Google Scholar
  71. 71. S. Shyng, T. Ferrigni and C. G. Nichols, Regulation of KATP channel activity by diazoxide and MgADP. Distinct functions of the two nucleotide binding folds of the sulfonylurea receptor,.(1997) 643–654; DOI: 10.1085/jgp.110.6.643.
    Open DOISearch in Google Scholar
  72. 72. F. M. Gribble, F. Reimann, R. Ashfield and F. M. Ashcroft, Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A,.(2000) 1256–1261.
    Search in Google Scholar
  73. 73. C. Moreau, A. L. Prost, R. Derand and M. Vivaudou, SUR, ABC proteins targeted by KATP channel openers,.(2005) 951–963; DOI: 10.1016/j.yjmcc.2004.11.030.
    Open DOISearch in Google Scholar
  74. 74. A. P. Babenko, G. Gonzalez and J. Bryan, Pharmaco-topology of sulfonylurea receptors. Separate domains of the regulatory subunits of K(ATP) channel isoforms are required for selective interaction with K(+) channel openers,.(2000) 717–720; DOI: 10.1074/jbc.275.2.717.
    Open DOISearch in Google Scholar
  75. 75. I. Uhde, A. Toman, I. Gross, C. Schwanstecher and M. Schwanstecher, Identification of the potassium channel opener site on sulfonylurea receptors,.(1999) 28079–28082; DOI: 10.1074/jbc.274.40.28079.
    Open DOISearch in Google Scholar
  76. 76. G. Edwards and A. H. Weston, Potassium channel openers and vascular smooth muscle relaxation,.(1990) 237–258; DOI: 10.1016/0163-7258(90)90082-D.
    Open DOISearch in Google Scholar
  77. 77. A. H. Weston, J. Longmore, D. T. Newgreen, G. Edwards, K. M. Bray and S. Duty, The potassium channel openers: a new class of vasorelaxants,.(1990) 306–313; DOI 10.1159/000158823.
    Search in Google Scholar
  78. 78. J. C. Clapham,, in(Ed. J. M. Evans), 1st ed., Taylor & Francis, London 1996, pp. 448.
    Search in Google Scholar
  79. 79. M. Burian, M. Piske, D. Petkovic and V. Mitrovic, Lack of anti-ischemic efficacy of the potassium channel opener bimakalim in patients with stable angina pectoris,.(2004) 37–46; DOI: 10.1023/B:CARD.0000025754.08942.03.
    Open DOISearch in Google Scholar
  80. 80. H. Ueda, Y. Nakayama, K. Tsumura, K. Yoshimaru, T. Hayashi and J. Yoshikawa, Intravenous nicorandil can reduce the occurrence of ventricular fibrillation and QT dispersion in patients with successful coronary angioplasty in acute myocardial infarction,.(2004) 625–629.
    Search in Google Scholar
  81. 81. I. S. Group, Effect of nicorandil on coronary events in patients with stable angina: the impact of nicorandil in angina (IONA) randomised trial,(2002) 1269–1275; DOI: 10.1016/S0140-6736(02)08265-X.
    Open DOISearch in Google Scholar
  82. 82. D. J. Milligan and A. M. Fields, Levosimendan: calcium sensitizer and inodilator,.(2010) 753–760; DOI: 10.1016/j.anclin.2010.08.003.
    Open DOISearch in Google Scholar
  83. 83. F. Follath, J. G. F. Cleland, H. Just, J. G. Y. Papp, H. Scholz, K. Peuhkurinen, V. P. Harjola, V. Mitrovic, M. Abdalla, E.-P. Sandell and L. Lehtonen, for the Steering Committee and Investigators of the Levosimendan Infusion versus Dobutamine (LIDO) Study, Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart failure (the LIDO study): a randomised double-blind trial,(2002) 196–202; DOI: 10.1016/S0140-6736(02)09455-2.
    Open DOISearch in Google Scholar
  84. 84. V. S. Moiseyev, P. Poder, N. Andrejevs, M. Y. Ruda, A. P. Golikov, L. B. Lazebnik, Z. D. Kobalava, L. A. Lehtonen, T. Laine, M. S. Nieminen, K. I. Lie and RUSSLAN Study Investigators, Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSS-LAN),.(2002) 1422–1432.
    Open DOISearch in Google Scholar
DOI: https://doi.org/10.1515/acph-2016-0006 | Journal eISSN: 1846-9558 | Journal ISSN: 1330-0075
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Language: English
Page range: 23 - 34
Accepted on: Sep 15, 2015
Published on: Mar 7, 2016
Published by: Croatian Pharmaceutical Society
In partnership with: Paradigm Publishing Services
Keywords:
ATP-sensitive potassium channels,
therapeutic agents,
diabetes,
cardiovascular,
inwardly rectifying potassium channels,
sulphonylurea receptor
Related subjects:
Pharmacy,
Pharmacy, other

© 2016 Hussein N. Rubaiy, published by Croatian Pharmaceutical Society
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

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