Rapidly Progressive Apical Hypertrophic Cardiomyopathy: Not Everything is What It Seems

Ahmed K. Mahmoud; Juan M. Farina; Kamal Awad; Milagros Pereyra; Isabel G. Scalia; Mohammed Tiseer Abbas; Timothy Barry; Said Alsidawi; Chadi Ayoub; Reza Arsanjani

doi:10.14797/mdcvj.1386

Rapidly Progressive Apical Hypertrophic Cardiomyopathy: Not Everything is What It Seems

Methodist DeBakey Cardiovascular Journal

Volume 20 (2024): Issue 1

By: Ahmed K. Mahmoud , Juan M. Farina , Kamal Awad , Milagros Pereyra , Isabel G. Scalia , Mohammed Tiseer Abbas , Timothy Barry , Said Alsidawi , Chadi Ayoub and Reza Arsanjani

Open Access

|Jun 2024

Abstract

Apical hypertrophic cardiomyopathy (HCM) is a rare variant of HCM. A 43-year-old female with a past medical history significant for hypertension and kidney transplantation presented with recurrent syncopal episodes and dyspnea on exertion. Electrocardiogram showed characteristic diffuse giant T-waves inversion, and cardiac magnetic resonance showed HCM with circumferential apical thickening. This case highlights the rapid development of apical HCM and its challenging diagnostic characteristics.

References

Hughes RK, Knott KD, Malcolmson J, et al. Advanced Imaging Insights in Apical Hypertrophic Cardiomyopathy. JACC Cardiovasc Imaging. 2020 Feb;13(2 Pt 2):624–30. doi: 10.1016/j.jcmg.2019.09.010
Open DOI Search in Google Scholar Back to article
Doeblin P, Gebker R, Pieske B, Kelle S. Late onset apical hypertrophic cardiomyopathy: a case report. Eur Heart J Case Rep. 2020 Dec 12;5(1):ytaa493. doi: 10.1093/ehjcr/ytaa493
Open DOI Search in Google Scholar Back to article
Hughes RK, Knott KD, Malcolmson J, et al. Apical Hypertrophic Cardiomyopathy: The Variant Less Known. J Am Heart Assoc. 2020 Mar 3;9(5):e015294. doi: 10.1161/JAHA.119.015294
Open DOI Search in Google Scholar Back to article
Lorenzini M, Norrish G, Field E, et al. Penetrance of Hypertrophic Cardiomyopathy in Sarcomere Protein Mutation Carriers. J Am Coll Cardiol. 2020 Aug 476(5):550–9. doi: 10.1016/j.jacc.2020.06.011
Open DOI Search in Google Scholar Back to article
Huang G, Fadl SA, Sukhotski S, Matesan M. Apical variant hypertrophic cardiomyopathy “multimodality imaging evaluation.” Int J Cardiovasc Imaging. 2020 Mar;36(3):553–61. doi: 10.1007/s10554-019-01739-x
Open DOI Search in Google Scholar Back to article
Parisi R, Mirabella F, Secco GG, Fattori R. Multimodality imaging in apical hypertrophic cardiomyopathy. World J Cardiol. 2014 Sep 26;6(9):916–23. doi: 10.4330/wjc.v6.i9.916
Open DOI Search in Google Scholar Back to article
Rouskas P, Katranas S, Zegkos T, et al. Apical Hypertrophic Cardiomyopathy: Diagnosis, Natural History, and Management. Cardiol Rev. 2023 Jul 3. Online ahead of print. doi: 10.1097/CRD.0000000000000579
Open DOI Search in Google Scholar Back to article

Articles in this issue

DOI: https://doi.org/10.14797/mdcvj.1386 | Journal eISSN: 1947-6108

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Language: English

Page range: 54 - 58

Submitted on: Apr 3, 2024

Accepted on: Apr 16, 2024

Published on: Jun 21, 2024

Published by: Houston Methodist DeBakey Heart & Vascular Center

In partnership with: Paradigm Publishing Services

Keywords:

syncope,

© 2024 Ahmed K. Mahmoud, Juan M. Farina, Kamal Awad, Milagros Pereyra, Isabel G. Scalia, Mohammed Tiseer Abbas, Timothy Barry, Said Alsidawi, Chadi Ayoub, Reza Arsanjani, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 20 (2024): Issue 1