Figure 1.
The role of macrophages and smooth muscle cells (SMCs) in atherogenesis.
Figure 2.
Macrophage- and smooth muscle cell (SMC)-related inflammatory pathways involved in atherosclerosis progression and plaque rapture. Bioactive molecules produced by macrophages are noted in red, the molecules produced by SMCs in blue. IL: interleukin, GM-CSF: granulocyte macrophage colony-stimulating factor, M-CSF: macrophage colony-stimulating factor, TNFα: tumor necrosis factor α, IFN-γ: interferon γ, CD40L: soluble CD40 ligand, MMP: matrix metalloproteinase, ROS: reactive oxygen species.