Local Inhibition of Macrophage and Smooth Muscle Cell Proliferation to Suppress Plaque Progression

Roman A. Sukhovershin; Naama E. Toledano Furman; Ennio Tasciotti; Barry H. Trachtenberg

doi:10.14797/mdcj-12-3-141

Local Inhibition of Macrophage and Smooth Muscle Cell Proliferation to Suppress Plaque Progression

Methodist DeBakey Cardiovascular Journal

Volume 12 (2016): Issue 3

By: Roman A. Sukhovershin, Naama E. Toledano Furman, Ennio Tasciotti and Barry H. Trachtenberg

Open Access

|Jul 2016

Abstract

Atherosclerosis is a complex process responsible for a major burden of cardiovascular morbidity and mortality. Macrophages and smooth muscle cells (SMCs) are abundant within atherosclerotic plaques. This review discusses the role of macrophages and SMCs in plaque progression and provides an overview of nanoparticle-based approaches and other current methods for local targeting of atherosclerotic plaques.

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Articles in this issue

DOI: https://doi.org/10.14797/mdcj-12-3-141 | Journal eISSN: 1947-6108

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Language: English

Page range: 141 - 145

Published on: Jul 1, 2016

Published by: Houston Methodist DeBakey Heart & Vascular Center

In partnership with: Paradigm Publishing Services

Keywords:

plaque,

© 2016 Roman A. Sukhovershin, Naama E. Toledano Furman, Ennio Tasciotti, Barry H. Trachtenberg, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.

Volume 12 (2016): Issue 3