Neural Mechanisms and Therapeutic Opportunities for Atrial Fibrillation
By: Takashi Kusayama, Juyi Wan, Yuan Yuan and Peng-Sheng Chen
References
-
Benjamin
E J
Chen
P S
Bild
D E
Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop
Circulation
2009
119
4
606
618
10.1161/CIRCULATIONAHA.108.825380 -
Chen
Peng-Sheng
Chen
Lan S.
Fishbein
Michael C.
Lin
Shien-Fong
Nattel
Stanley
Role of the Autonomic Nervous System in Atrial Fibrillation
Circulation Research
2014
114
9
1500
1515
0009-7330, 1524-4571 10.1161/circresaha.114.303772 Ovid Technologies (Wolters Kluwer Health)https://dx.doi.org/10.1161/circresaha.114.303772 -
Armour
J. Andrew
Murphy
David A.
Yuan
Bing-Xiang
MacDonald
Sara
Hopkins
David A.
Gross and microscopic anatomy of the human intrinsic cardiac nervous system
The Anatomical Record
1997
247
2
289
298
0003-276X, 1097-0185 10.1002/(sici)1097-0185(199702)247:2<;289::aid-ar15>3.0.co;2-l Wileyhttps://dx.doi.org/10.1002/(sici)1097-0185(199702)247:2<289::aid-ar15>3.0.co;2-l - Kawashima T The autonomic nervous system of the human heart with special reference to its origin, course, and peripheral distribution Anat Embryol 2005 209 6 425 463
- Shen M J Hao-Che C Park H W Low-level vagus nerve stimulation upregulates small conductance calcium-activated potassium channels in the stellate ganglion Heart Rhythm 2013 10 6 910 915
-
Apostolova
G.
Loy
B.
Dorn
R.
Dechant
G.
The Sympathetic Neurotransmitter Switch Depends on the Nuclear Matrix Protein Satb2
Journal of Neuroscience
2010
30
48
16356
16364
0270-6474, 1529-2401 10.1523/jneurosci.3502-10.2010 Society for Neurosciencehttps://dx.doi.org/10.1523/jneurosci.3502-10.2010 -
Chiou
Chuen-Wang
Eble
John N.
Zipes
Douglas P.
Efferent Vagal Innervation of the Canine Atria and Sinus and Atrioventricular Nodes
Circulation
1997
95
2573
2584
0009-7322, 1524-4539 Ovid Technologies (Wolters Kluwer Health)10.1161/01.cir.95.11.2573 https://dx.doi.org/10.1161/01.cir.95.11.2573 -
Kawagishi
K
Fukushima
N
Yokouchi
K
Sumitomo
N
Kakegawa
A
Moriizumi
T
Tyrosine hydroxylase-immunoreactive fibers in the human vagus nerve
J Clin Neurosci
2008
15
9
1023
1026
10.1016/j.jocn.2007.08.032 Kakegawa A, Moriizumi - Seki A Green H R Lee T D Sympathetic nerve fibers in human cervical and thoracic vagus nerves Heart Rhythm 2014 11 8 1411 1418
-
Pauza
Dainius H.
Skripka
Valdas
Pauziene
Neringa
Morphology of the Intrinsic Cardiac Nervous System in the Dog: A Whole-Mount Study Employing Histochemical Staining with Acetylcholinesterase
Cells Tissues Organs
2002
172
4
297
320
1422-6405, 1422-6421 10.1159/000067198 S. Karger AGhttps://dx.doi.org/10.1159/000067198 - Hou Y Scherlag B J Lin J Ganglionated plexi modulate extrinsic cardiac autonomic nerve input: effects on sinus rate, atrioventricular conduction, refractoriness, and inducibility of atrial fibrillation J Am Coll Cardiol 2007 50 1 61 69
-
Tan
Alex Y.
Li
Hongmei
Wachsmann-Hogiu
Sebastian
Chen
Lan S.
Chen
Peng-Sheng
Fishbein
Michael C.
Autonomic Innervation and Segmental Muscular Disconnections at the Human Pulmonary Vein-Atrial Junction
Journal of the American College of Cardiology
2006
48
1
132
143
0735-1097 10.1016/j.jacc.2006.02.054 Elsevier BVhttps://dx.doi.org/10.1016/j.jacc.2006.02.054 -
Bers
Donald M.
Cardiac excitation–contraction coupling
Nature
2002
415
6868
198
205
0028-0836, 1476-4687 10.1038/415198a Springer Science and Business Media LLChttps://dx.doi.org/10.1038/415198a - Wijffels M C Kirchhof C J Dorland R Allessie M A Atrial fibrillation begets atrial fibrillation. A study in awake chronically instrumented goats Circulation 1995 92 7 1954 68
-
Fareh
Samir
Villemaire
Christine
Nattel
Stanley
Importance of Refractoriness Heterogeneity in the Enhanced Vulnerability to Atrial Fibrillation Induction Caused by Tachycardia-Induced Atrial Electrical Remodeling
Circulation
1998
98
20
2202
2209
0009-7322, 1524-4539 10.1161/01.cir.98.20.2202 Ovid Technologies (Wolters Kluwer Health)https://dx.doi.org/10.1161/01.cir.98.20.2202 -
Burashnikov
Alexander
Antzelevitch
Charles
Reinduction of Atrial Fibrillation Immediately After Termination of the Arrhythmia Is Mediated by Late Phase 3 Early Afterdepolarization–Induced Triggered Activity
Circulation
2003
107
18
2355
2360
0009-7322, 1524-4539 10.1161/01.cir.0000065578.00869.7c Ovid Technologies (Wolters Kluwer Health)https://dx.doi.org/10.1161/01.cir.0000065578.00869.7c -
PATTERSON
EUGENE
JACKMAN
WARREN M.
BECKMAN
KAREN J.
LAZZARA
RALPH
LOCKWOOD
DEBORAH
SCHERLAG
BENJAMIN J.
WU
RICHARD
PO
SUNNY
Spontaneous Pulmonary Vein Firing in Man: Relationship to Tachycardia-Pause Early Afterdepolarizations and Triggered Arrhythmia in Canine Pulmonary Veins In Vitro
Journal of Cardiovascular Electrophysiology
2007
18
1067
1075
1045-3873, 1540-8167 Wiley10.1111/j.1540-8167.2007.00909.x https://dx.doi.org/10.1111/j.1540-8167.2007.00909.x - Verma A Jiang C Y Betts T R Approaches to catheter ablation for persistent atrial fibrillation N Engl J Med 2015 372 1812 1834
-
Demaurex
N.
CELL BIOLOGY: Apoptosis--the Calcium Connection
Science
2003
300
5616
65
67
0036-8075, 1095-9203 10.1126/science.1083628 American Association for the Advancement of Science (AAAS)https://dx.doi.org/10.1126/science.1083628 -
Andiné
Peter
Jacobson
Ingemar
Hagberg
Henrik
Calcium Uptake Evoked by Electrical Stimulation is Enhanced Postischemically and Precedes Delayed Neuronal Death in CA1 of Rat Hippocampus: Involvement of N-Methyl-D-Aspartate Receptors
Journal of Cerebral Blood Flow & Metabolism
1988
8
6
799
807
0271-678X, 1559-7016 10.1038/jcbfm.1988.135 SAGE Publicationshttps://dx.doi.org/10.1038/jcbfm.1988.135 - Wan J Chen M Yuan Y Antiarrhythmic and proarrhythmic effects of subcutaneous nerve stimulation in ambulatory dogs Heart Rhythm 2019 16 8 1251 60
- Yuan Y Jiang Z Zhao Y Long-term intermittent high-amplitude subcutaneous nerve stimulation reduces sympathetic tone in ambulatory dogs Heart Rhythm 2018 15 3 451 460
-
Yuan
Y
Liu
X
Wan
J
Subcutaneous nerve stimulation for rate control in ambulatory dogs with persistent atrial fibrillation
Heart Rhythm
2019
16
9
1383
1391
10.1016/j.hrthm.2019.05.029 -
Kusayama
Takashi
Wan
Juyi
Yuan
Yuan
Liu
Xiao
Li
Xiaochun
Shen
Changyu
Fishbein
Michael C.
Everett
Thomas H.
Chen
Peng-Sheng
Effects of subcutaneous nerve stimulation with blindly inserted electrodes on ventricular rate control in a canine model of persistent atrial fibrillation
Heart Rhythm
2021
18
2
261
270
1547-5271 10.1016/j.hrthm.2020.09.009 Elsevier BVhttps://dx.doi.org/10.1016/j.hrthm.2020.09.009 -
Katritsis
Demosthenes G.
Pokushalov
Evgeny
Romanov
Alexander
Giazitzoglou
Eleftherios
Siontis
George C.M.
Po
Sunny S.
Camm
A. John
Ioannidis
John P.A.
Autonomic Denervation Added to Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation
Journal of the American College of Cardiology
2013
62
24
2318
2325
0735-1097 10.1016/j.jacc.2013.06.053 Elsevier BVhttps://dx.doi.org/10.1016/j.jacc.2013.06.053 -
Pokushalov
Evgeny
Romanov
Alexandr
Katritsis
Demosthenes G.
Artyomenko
Sergey
Shirokova
Natalya
Karaskov
Alexandr
Mittal
Suneet
Steinberg
Jonathan S.
Ganglionated plexus ablation vs linear ablation in patients undergoing pulmonary vein isolation for persistent/long-standing persistent atrial fibrillation: A randomized comparison
Heart Rhythm
2013
10
9
1280
1286
1547-5271 10.1016/j.hrthm.2013.04.016 Elsevier BVhttps://dx.doi.org/10.1016/j.hrthm.2013.04.016 -
Krum
Henry
Schlaich
Markus
Whitbourn
Rob
Sobotka
Paul A
Sadowski
Jerzy
Bartus
Krzysztof
Kapelak
Boguslaw
Walton
Anthony
Sievert
Horst
Thambar
Suku
Abraham
William T
Esler
Murray
Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study
The Lancet
2009
373
9671
1275
1281
0140-6736 10.1016/s0140-6736(09)60566-3 Elsevier BVhttps://dx.doi.org/10.1016/s0140-6736(09)60566-3 -
Esler
M.
Renal denervation for hypertension: observations and predictions of a founder
European Heart Journal
2014
35
18
1178
1185
0195-668X, 1522-9645 10.1093/eurheartj/ehu091 Oxford University Press (OUP)https://dx.doi.org/10.1093/eurheartj/ehu091 -
Linz
Dominik
Mahfoud
Felix
Schotten
Ulrich
Ukena
Christian
Neuberger
Hans-Ruprecht
Wirth
Klaus
Böhm
Michael
Renal Sympathetic Denervation Suppresses Postapneic Blood Pressure Rises and Atrial Fibrillation in a Model for Sleep Apnea
Hypertension
2012
60
1
172
178
0194-911X, 1524-4563 10.1161/hypertensionaha.112.191965 Ovid Technologies (Wolters Kluwer Health)https://dx.doi.org/10.1161/hypertensionaha.112.191965 -
Linz
Dominik
van Hunnik
Arne
Hohl
Mathias
Mahfoud
Felix
Wolf
Milan
Neuberger
Hans-Ruprecht
Casadei
Barbara
Reilly
Svetlana N.
Verheule
Sander
Böhm
Michael
Schotten
Ulrich
Catheter-Based Renal Denervation Reduces Atrial Nerve Sprouting and Complexity of Atrial Fibrillation in Goats
Circulation: Arrhythmia and Electrophysiology
2015
8
2
466
474
1941-3149, 1941-3084 10.1161/circep.114.002453 Ovid Technologies (Wolters Kluwer Health)https://dx.doi.org/10.1161/circep.114.002453 -
Tsai
W C
Chan
Y H
Chinda
K
Effects of renal sympathetic denerva- tion on the stellate ganglion and brain stem in dogs
Heart Rhythm
2017
14
2
255
62
10.1016/j.hrthm.2016.10.003 - Steinberg J S Shabanov V Ponomarev D Effect of Renal Denervation and Catheter Ablation vs Catheter Ablation Alone on Atrial Fibrillation Recurrence Among Patients With Paroxysmal Atrial Fibrillation and Hyper- tension: The ERADICATE-AF Randomized Clinical Trial JAMA 2020 323 3 248 55
-
Feyz
Lida
Theuns
Dominic A.
Bhagwandien
Rohit
Strachinaru
Mihai
Kardys
Isabella
Van Mieghem
Nicolas M.
Daemen
Joost
Atrial fibrillation reduction by renal sympathetic denervation: 12 months’ results of the AFFORD study
Clinical Research in Cardiology
2019
108
6
634
642
1861-0684, 1861-0692 10.1007/s00392-018-1391-3 Springer Science and Business Media LLChttps://dx.doi.org/10.1007/s00392-018-1391-3 -
Patterson
Eugene
Po
Sunny S.
Scherlag
Benjamin J.
Lazzara
Ralph
Triggered firing in pulmonary veins initiated by in vitro autonomic nerve stimulation
Heart Rhythm
2005
2
624
631
1547-5271 Elsevier BV10.1016/j.hrthm.2005.02.012 https://dx.doi.org/10.1016/j.hrthm.2005.02.012 - Yu L Scherlag B J Li S Low-level vagosympathetic nerve stimulation inhibits atrial fibrillation inducibility: direct evidence by neural recordings from intrinsic cardiac ganglia J Cardiovasc Electrophysiol 2011 22 4 455 63
- Sheng X Scherlag B J Yu L Prevention and reversal of atrial fibrillation inducibility and autonomic remodeling by low-level vagosympathetic nerve stimulation J Am Coll Cardiol 2011 57 5 563 71
- Shen M J Shinohara T Park H W Continuous low-level vagus nerve stimulation reduces stellate ganglion nerve activity and paroxysmal atrial tach- yarrhythmias in ambulatory canines Circulation 1920 123 2204 2216
-
Adelman
John P.
Maylie
James
Sah
Pankaj
Small-Conductance Ca2+-Activated K+Channels: Form and Function
Annual Review of Physiology
2012
74
1
245
269
0066-4278, 1545-1585 10.1146/annurev-physiol-020911-153336 Annual Reviewshttps://dx.doi.org/10.1146/annurev-physiol-020911-153336 - Chinda K Tsai W C Chan Y H Intermittent left cervical vagal nerve stimulation damages the stellate ganglia and reduces the ventricular rate during sustained atrial fibrillation in ambulatory dogs Heart Rhythm 2016 13 3 771 80
-
Stavrakis
Stavros
Humphrey
Mary Beth
Scherlag
Benjamin
Iftikhar
Omer
Parwani
Purvi
Abbas
Mubasher
Filiberti
Adrian
Fleming
Christian
Hu
Yanqing
Garabelli
Paul
McUnu
Arthur
Peyton
Marvin
Po
Sunny S.
Low-Level Vagus Nerve Stimulation Suppresses Post-Operative Atrial Fibrillation and Inflammation
JACC: Clinical Electrophysiology
2017
3
9
929
938
2405-500X 10.1016/j.jacep.2017.02.019 Elsevier BVhttps://dx.doi.org/10.1016/j.jacep.2017.02.019 - Chen M Yu L Liu Q Low level tragus nerve stimulation is a non-invasive approach for anti-atrial fibrillation via preventing the loss of connexins Int J Cardiol 2015 179 144 149
-
Stavrakis
Stavros
Humphrey
Mary Beth
Scherlag
Benjamin J.
Hu
Yanqing
Jackman
Warren M.
Nakagawa
Hiroshi
Lockwood
Deborah
Lazzara
Ralph
Po
Sunny S.
Low-Level Transcutaneous Electrical Vagus Nerve Stimulation Suppresses Atrial Fibrillation
Journal of the American College of Cardiology
2015
65
9
867
875
0735-1097 10.1016/j.jacc.2014.12.026 Elsevier BVhttps://dx.doi.org/10.1016/j.jacc.2014.12.026
DOI: https://doi.org/10.14797/FVDN2224 | Journal eISSN: 1947-6108
Language: English
Page range: 43 - 47
Published on: Jan 1, 2021
Published by: Houston Methodist DeBakey Heart & Vascular Center
In partnership with: Paradigm Publishing Services
Keywords:
© 2021 Takashi Kusayama, Juyi Wan, Yuan Yuan, Peng-Sheng Chen, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.