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Under Pressure: Right Heart Catheterization and Provocative Testing for Diagnosing Pulmonary Hypertension Cover

Under Pressure: Right Heart Catheterization and Provocative Testing for Diagnosing Pulmonary Hypertension

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Open Access
|Jul 2021

References

  1. Galiè N, Humbert M, Vachiery J-L, et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J. 2016 Jan; 37(1): 67119. doi: 10.1093/eurheartj/ehv317.
  2. Grünig E, Barner A, Bell M, et al. Non-invasive diagnosis of pulmonary hypertension: ESC/ERS Guidelines with Updated Commentary of the Cologne Consensus Conference 2011. Int J Cardiol. 2011 Dec; 154 Suppl 1: S312. doi: 10.1016/S0167-5273(11)70488-0.
  3. Hoeper MM, Lee SH, Voswinckel R, et al. Complications of right heart catheterization procedures in patients with pulmonary hypertension in experienced centers. J Am Coll Cardiol. 2006 Dec 19; 48(12): 254652. doi: 10.1016/j.jacc.2006.07.061.
  4. Simonneau G, Montani D, Celermajer DS, et al. Haemodynamic definitions and updated clinical classification of pulmonary hypertension. Eur Respir J. 2019 Jan 24; 53(1): 1801913. doi: 10.1183/13993003.01913-2018.
  5. Farber HW, Gibbs S. Under pressure: pulmonary hypertension associated with left heart disease. Eur Respir Rev. 2015 Dec; 24(138): 66573. doi: 10.1183/16000617.0059-2015.
  6. Ragosta M. Textbook of Clinical Hemodynamics E-Book. The Netherlands: Elsevier Health Sciences; 2017. 328 p.
  7. Reddy YNV, El-Sabbagh A, Nishimura RA. Comparing Pulmonary Arterial Wedge Pressure and Left Ventricular End Diastolic Pressure for Assessment of Left-Sided Filling Pressures. JAMA Cardiol. 2018 Jun 1; 3(6): 4534. doi: 10.1001/jamacardio.2018.0318.
  8. Mascherbauer J, Zotter-Tufaro C, Duca F, et al. Wedge Pressure Rather Than Left Ventricular End-Diastolic Pressure Predicts Outcome in Heart Failure With Preserved Ejection Fraction. JACC Heart Fail. 2017 Nov; 5(11): 795801. doi: 10.1016/j.jchf.2017.08.005.
  9. Deano RC, Frost A, Visovatti SH, Glassner C, Gomberg-Maitland M, Rubenfire M. RePHerral Study-A Multi-Center Study Of The Referral Of Pulmonary Hypertension Patients To Tertiary Pulmonary Hypertension Centers. Am J Respir Crit Care Med. 2020; 201: A4103. doi: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.A4103.
  10. Ryan JJ, Rich JD, Thiruvoipati T, Swamy R, Kim GH, Rich S. Current practice for determining pulmonary capillary wedge pressure predisposes to serious errors in the classification of patients with pulmonary hypertension. Am Heart J. 2012 Apr; 163(4): 58994. doi: 10.1016/j.ahj.2012.01.024.
  11. Sharma A, Obiagwu C, Mezue K, et al. Role of vasodilator testing in pulmonary hypertension. Prog Cardiovasc Dis. Jan-Feb 2016; 58(4): 42533. doi: 10.1016/j.pcad.2015.09.006.
  12. Members WC, McLaughlin VV, Archer SL, et al. ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation task force on expert consensus documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association. Circulation. 2009 Apr 28; 119(16): 225094. doi: 10.1161/CIRCULATIONAHA.109.192230.
  13. Oliveira EC, Ribeiro ALP, Amaral CFS. Adenosine for vasoreactivity testing in pulmonary hypertension: a head-to-head comparison with inhaled nitric oxide. Respir Med. 2010 Apr; 104(4): 60611. doi: 10.1016/j.rmed.2009.11.010.
  14. Hoeper MM, Olschewski H, Ghofrani HA, et al. A comparison of the acute hemodynamic effects of inhaled nitric oxide and aerosolized iloprost in primary pulmonary hypertension. J Am Coll Cardiol. 2000 Jan; 35(1): 17682. doi: 10.1016/s0735-1097(99)00494-5.
  15. Sitbon O, Humbert M, Jaïs X, et al. Long-term response to calcium channel blockers in idiopathic pulmonary arterial hypertension. Circulation. 2005 Jun 14; 111(23): 310511. doi: 10.1161/CIRCULATIONAHA.104.488486.
  16. Guglin M, Mehra S, Mason TJ. Comparison of drugs for pulmonary hypertension reversibility testing: A meta-analysis. Pulm Circ. 2013 Apr; 3(2): 40613. doi: 10.4103/2045-8932.113180.
  17. Esfandiari S, Wright SP, Goodman JM, et al. Pulmonary Artery Wedge Pressure Relative to Exercise Work Rate in Older Men and Women. Med Sci Sports Exerc. 2017 Jul; 49(7): 12971304. doi: 10.1249/MSS.0000000000001227.
  18. Kovacs G, Berghold A, Scheidl S, Olschewski HJERJ. Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review. Eur Respir J. 2009 Oct; 34(4): 88894. doi: 10.1183/09031936.00145608.
  19. American College of Cardiology [Internet]. Washington, DC: Heart House; c2021. Felipe Valle MSW, PhD; Susanna Mak, MD, PhD. The Utility of Fluid Challenge or Exercise During RHC in the Evaluation of PAH; 2018 Dec 18 [cited 2021 Feb 5]. Available from: https://www.acc.org/latest-in-cardiology/articles/2018/12/18/11/27/the-utility-of-fluid-challenge-or-exercise-during-rhc-in-the-evaluation-of-pah.
  20. Wright SP, Esfandiari S, Gray T, et al. The pulmonary artery wedge pressure response to sustained exercise is time-variant in healthy adults. Heart. 2016 Mar; 102(6): 43843. doi: 10.1136/heartjnl-2015-308592.
  21. Jain CC, Borlaug BA. Performance and Interpretation of Invasive Hemodynamic Exercise Testing. Chest. 2020 Nov; 158(5): 211929. doi: 10.1016/j.chest.2020.05.552.
  22. Kovacs G, Herve P, Barbera JA, et al. An official European Respiratory Society statement: pulmonary haemodynamics during exercise. Eur Respir J. 2017 Nov 22; 50(5): 1700578. doi: 10.1183/13993003.00578-2017.
  23. Blumberg FC, Arzt M, Lange T, Schroll S, Pfeifer M, Wensel RJE. Impact of right ventricular reserve on exercise capacity and survival in patients with pulmonary hypertension. Eur J Heart Fail. 2013 Jul; 15(7): 7715. doi: 10.1093/eurjhf/hft044.
  24. Chaouat A, Sitbon O, Mercy M, et al. Prognostic value of exercise pulmonary haemodynamics in pulmonary arterial hypertension. Eur Respir J. 2014 Sep; 44(3): 70413. doi: 10.1183/09031936.00153613.
  25. Bonno EL, Viray MC, Jackson GR, Modern Right Heart Catheterization: Beyond Simple Hemodynamics. Adv Pulm Hypertens. 2020 Jan; 19(1): 615. DOI: 10.21693/1933-088X-19.1.6.
  26. Lewis GD, Bossone E, Naeije R, et al. Pulmonary vascular hemodynamic response to exercise in cardiopulmonary diseases. Circulation. 2013 Sep 24; 128(13): 14709. doi: 10.1161/CIRCULATIONAHA.112.000667.
  27. Herve P, Lau EM, Sitbon O, et al. Criteria for diagnosis of exercise pulmonary hypertension. Eur Respir J. 2015; 46(3): 72837. doi: 10.1183/09031936.00021915.
  28. Arunachalam A, Chaisson NF, Tonelli AR. Methods to improve the yield of right heart catheterization in pulmonary hypertension. Respir Med X. 2020 Nov; 2: 100015. doi: 10.1016/j.yrmex.2020.100015.
  29. Portillo K, Torralba Y, Blanco I, et al. Pulmonary hemodynamic profile in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2015; 10: 1313. doi: 10.2147/COPD.S78180.
  30. Tolle JJ, Waxman AB, Van Horn TL, Pappagianopoulos PP, Systrom DM. Exercise-induced pulmonary arterial hypertension. Circulation. 2008 Nov 18; 118(21): 21839. doi: 10.1161/circulationaha.108.787101.
  31. Dorfs S, Zeh W, Hochholzer W, et al. Pulmonary capillary wedge pressure during exercise and long-term mortality in patients with suspected heart failure with preserved ejection fraction. Eur Heart J. 2014 Nov 21; 35(44): 310312. doi: 10.1093/eurheartj/ehu315.
  32. Fujimoto N, Borlaug BA, Lewis GD, et al. Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure. Circulation. 2013 Jan 1; 127(1): 5562. doi: 10.1161/CIRCULATIONAHA.112.111302.
  33. D’Alto M, Romeo E, Argiento P, et al. Clinical relevance of fluid challenge in patients evaluated for pulmonary hypertension. Chest. 2017 Jan; 151(1): 11926. doi: 10.1016/j.chest.2016.08.1439.
  34. Andersen MJ, Olson TP, Melenovsky V, Kane GC, Borlaug BA. Differential hemodynamic effects of exercise and volume expansion in people with and without heart failure. Circ Heart Fail. 2015 Jan; 8(1): 418. doi: 10.1161/CIRCHEARTFAILURE.114.001731.
  35. Vachiéry J-L, Tedford RJ, Rosenkranz S, et al. Pulmonary hypertension due to left heart disease. Eur Respir J. 2019 Jan 24; 53(1): 1801897. doi: 10.1183/13993003.01897-2018.
  36. Jawad A, Tonelli AR, Chatburn RL, Wang X, Hatipoglu U. Impact of intrathoracic pressure in the assessment of pulmonary hypertension in overweight patients. Ann Am Thorac Soc. 2017 Dec; 14(12): 18613. doi: 10.1513/Annal-sATS.201704-331RL.
  37. Iwano H, Tsujinaga S, Iwami D, Asakawa N, Yamada S, Anzai T. Clinical utility of echocardiographic hemodynamic monitoring during manual compression of arteriovenous shunt in a patient with high-output heart failure. CASE (Phila). 2018 May 1; 2(3): 1038. doi: 10.1016/j.case.2017.12.001.
  38. Domingo E, Grignola JC, Aguilar R, et al. Impairment of pulmonary vascular reserve and right ventricular systolic reserve in pulmonary arterial hypertension. BMC Pulm Med. 2014 Apr 24; 14(1): 69. doi: 10.1186/1471-2466-14-69.
  39. Sharma T, Lau EM, Choudhary P, et al. Dobutamine stress for evaluation of right ventricular reserve in pulmonary arterial hypertension. Eur Respir J. 2015 Mar; 45(3): 7008. doi: 10.1183/09031936.00089914.
  40. Givertz MM, Hare JM, Loh E, Gauthier DF, Colucci WS. Effect of Bolus Milrinone on Hemodynamic Variables and Pulmonary Vascular Resistance in Patients with Severe Left Ventricular Dysfunction: A Rapid Test for Reversibility of Pulmonary Hypertension. J Am Coll Cardiol. 1996 Dec; 28(7): 177580. doi: 10.1016/S0735-1097(96)00399-3.
DOI: https://doi.org/10.14797/AFUI4711 | Journal eISSN: 1947-6108
Language: English
Page range: 92 - 100
Accepted on: Jan 7, 2021
Published on: Jul 1, 2021
Published by: Houston Methodist DeBakey Heart & Vascular Center
In partnership with: Paradigm Publishing Services

© 2021 Isaac Tea, Imad Hussain, published by Houston Methodist DeBakey Heart & Vascular Center
This work is licensed under the Creative Commons Attribution-NonCommercial 4.0 License.