Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer
Authors
Sanjit K Roy
Department of Pharmacology, Toxicology and Therapeutics, and Medicine, The University of Kansas Cancer Center, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA
Rakesh K Srivastava
Department of Pharmacology, Toxicology and Therapeutics, and Medicine, The University of Kansas Cancer Center, The University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS, 66160, USA
Sharmila Shankar
Department of Pathology and Laboratory Medicine, The University of Kansas Cancer Center, The University of Kansas Medical Center, 3901
Rainbow Boulevard, Kansas City, KS, 66160, USA
DOI: https://doi.org/10.1186/1750-2187-5-10 | Journal eISSN: 1750-2187
Language: English
Published on: Jul 19, 2010
Published by: Danny N. Dhanasekaran
In partnership with: Paradigm Publishing Services
© 2010 Sanjit K Roy, Rakesh K Srivastava, Sharmila Shankar, published by Danny N. Dhanasekaran
This work is licensed under the Creative Commons Attribution 4.0 License.