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The Analysis of Regulatory DNA: Current DevelopmentsKnowledge and Applications Uncovering Gene Regulation Cover

The Analysis of Regulatory DNA: Current DevelopmentsKnowledge and Applications Uncovering Gene Regulation

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|Nov 2013
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A major goal of integrative research is understanding regulatory networks to such an extent as to allow researchers to model developmental and stress responses. Regulatory networks of living systems include complex and vast interactions between proteinsmetabolitesRNAvarious signaling molecules and DNA. One aspect of systems biology is understanding the dynamics of protein-DNA interactions affecting gene expression that are caused by transcription factors (TFs) and chromatin remodeling factors. This e-book provides a resource for summarizing current knowledge eukaryotic transcription and explores cis-elements and methods for their analysisprediction and discovery. The book also presents an overview of exploring gene regulatory networkschromatinand miRNAs. Information about state-of-the-art techniques for the determination of TF - cis-element interactions in vivo and in silico give cutting edge insights on how genomic-scale research is being approached. The Analysis of Regulatory DNA provides readers with both the necessary background knowledge and provocativeup-to-date insights aimed at sparking new and vibrant experimental designs for understanding and predicting cis-elements in the eukaryotic genome.
PDF ISBN: 978-1-60805-492-3
Publisher: Bentham Science
Copyright owner: © 2013 Bentham Science Publishers
Publication date: 2013
Language: English
Pages: 225
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