Protein Misfolding Disorders: A Trip into the ER

Publisher:Bentham Science

By: Claudio Hetz

Paid access

|Jan 2009

E-Book €53.99Institutions €228.95

Description

Neurodegenerative disorders such as Amyotrophic lateral sclerosis (ALS) Alzheimer's disease (AD) Parkinson's disease (PD) Prion-related disorders (PrD) and Huntington's disease (HD) share a common neuropathology primarily featuring the presence of abnormal protein inclusions containing specific misfolded proteins. These groups of diseases are now classified as Protein Misfolding Disorders. This Ebook gives a comprehensive overview of the possible mechanisms involved in Protein Misfolding Disorders and possible therapeutic strategies to treat these diseases. The Ebook provides the most recent evidence addressing the role of cellular stress responses to neurological diseases along with therapeutic strategies to alleviate ER stress in a disease context.

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PDF ISBN: 978-1-60805-013-0

Publisher: Bentham Science

Publication date: 2009

Language: English

Pages: 156

Related subjects:

Medicine,

Clinical medicine,

Neurology