Fig. 1.
The Critical Care Shift: From Tool-Centric Overload to Patient-Centric Biotechnology Ecosystems. (A) The Bioengineering Silhouette: A vertical paradigm where independent devices and black-box algorithms flood the clinical workspace with fragmented data streams, leading to alarm fatigue and clinical noise. (B) The Biotechnology Platform: A horizontal, integrated convergence platform where advanced computation, predictive models, and mechanical organ support are orchestrated entirely around dynamic host physiology and translated through active clinical reasoning. AI – artificial intelligence; ECMO – extracorporeal membrane oxygenation