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Early clinical outcomes and quality of life assessment after HeartMate 3 implantation: A single-centre descriptive study Cover

Early clinical outcomes and quality of life assessment after HeartMate 3 implantation: A single-centre descriptive study

Open Access
|Apr 2026

Figures & Tables

Key outcomes (demographics, baseline clinical status, complications, early outcomes, quality of life outcomes)_ NYHA-New York heart Association; INTERMACS-Interagency Registry for Mechanically Assisted Circulatory Support; COPD-Chronic Obstructive Pulmonary Disease; QoL-Quality of Life_

VariableValue
Demographics
Age, years (mean ± SD)47.2 ± 12.3
Male sex, n (%)11 (84.6)
Implant strategy – Bridge-to-transplant, n (%)10 (76.9)
Implant strategy – Destination therapy, n (%)3 (23.1)

Baseline clinical status
NYHA class IV, n (%)9 (69.2)
INTERMACS I–II, n (%)2 (15.4)
INTERMACS III–IV, n (%)3 (23.1)
INTERMACS V, n (%)8 (61.5)
EuroSCORE II low risk (<4%), n (%)2 (15.4)
EuroSCORE II intermediate risk (4–8%), n (%)7 (53.8)
EuroSCORE II high risk (>8%), n (%)4 (30.8)

Postoperative complications
Perioperative bleeding, n (%)8 (61.5)
Right ventricular failure, n (%)3 (23.1)
Pneumonia, n (%)3 (23.1)
Ischemic stroke, n (%)1 (7.7)
Gastrointestinal bleeding, n (%)1 (7.7)

Early outcomes
Early mortality (≤45 days), n (%)3 (23.1)
Survivors at follow-up, n (%)10 (76.9)

Quality of life outcomes
Reported overall QoL improvement, n10
QoL rated good or excellent, n7
Independent ambulation regained, n10
Resumed regular social interactions, n7
Early postoperative psychological distress, n6
Regular physical activity (>3 days/week), n9
Sleep disturbances early post-implant, n7
Transient suicidal ideation post-implant, n3
Reported confidence in device management, n9
Local driveline infection/trauma, n5
DOI: https://doi.org/10.62838/jccm-2026-0015 | Journal eISSN: 2393-1817 | Journal ISSN: 2393-1809
Language: English
Page range: 281 - 290
Submitted on: Sep 25, 2025
Accepted on: Jan 20, 2026
Published on: Apr 30, 2026
In partnership with: Paradigm Publishing Services
Publication frequency: 4 issues per year

© 2026 Samuel Michelini, Marius Mihai Harpa, Dan Nistor, David-Emanuel Anitei, Alexandru Stan, Paul Calburean, Emil Marian Arbanasi, Dragos-Florin Baba, Sabrina Mancino, Horatiu Suciu, published by University of Medicine, Pharmacy, Science and Technology of Targu Mures
This work is licensed under the Creative Commons Attribution 4.0 License.