Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 diabetes mellitus

BOGDAN MINEA; VALENTIN NASTASA; ANNA KOLECKA; MAGDALENA MARES; NARCISA MARANGOCI; IRINA ROSCA; MARIANA PINTEALA; MONICA HANCIANU; MIHAI MARES

doi:10.5604/17331331.1197327

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Etiologic Agents and Antifungal Susceptibility of Oral Candidosis from Romanian patients with HIV-infection or type 1 diabetes mellitus

Polish Journal of Microbiology

Volume 65 (2016): Issue 1 (March 2016)

By: BOGDAN MINEA, VALENTIN NASTASA, ANNA KOLECKA, MAGDALENA MARES, NARCISA MARANGOCI, IRINA ROSCA, MARIANA PINTEALA, MONICA HANCIANU and MIHAI MARES

Open Access

|Mar 2016

Abstract

This is the first Romanian investigation of oral candidosis in patients suffering of HIV-infection or type 1 diabetes mellitus (T1DM). Candida albicans was the dominant species in both types of isolates: n = 14 (46.7%) in T1DM, n = 60 (69.8%) in HIV. The most frequent nonalbicans Candida spp. were Candida kefyr (n = 6; 20%) in T1DM and Candida dubliniensis (n = 8; 9.3%) in HIV. Resistance to fluconazole was detected only in the HIV non-albicans Candida group (n = 8; 9.3%). All isolates were susceptible to VOR. The experimental drug MXP had MIC values equal or close to the ones of VOR. Echinocandin resistance was more frequent than azole resistance.

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Articles in this issue

DOI: https://doi.org/10.5604/17331331.1197327 | Journal eISSN: 2544-4646 | Journal ISSN: 1733-1331

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Language: English

Page range: 123 - 129

Submitted on: Mar 11, 2015

Accepted on: Apr 21, 2015

Published on: Mar 15, 2016

Published by: Polish Society of Microbiologists

In partnership with: Paradigm Publishing Services

Publication frequency: 4 issues per year

Keywords:

antifungal susceptibility,

MXP-4509,

oral candidosis,

Romanian HIV and diabetes patients

Related subjects:

Life sciences,

Microbiology and virology

© 2016 BOGDAN MINEA, VALENTIN NASTASA, ANNA KOLECKA, MAGDALENA MARES, NARCISA MARANGOCI, IRINA ROSCA, MARIANA PINTEALA, MONICA HANCIANU, MIHAI MARES, published by Polish Society of Microbiologists
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Volume 65 (2016): Issue 1 (March 2016)