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The assessment of phagocytic and bactericidal activity of platelets and plasma bactericidal activity in late preterm newborns*

Postępy Higieny i Medycyny Doświadczalnej
Volume 75 (2021): Issue 1 (January 2021)
By:
Open Access
|Jan 2021

Figures & Tables

Fig. 1

Correlation between the phagocytic index and birth weight (g) (R = 0.25, p = 0.003)
Correlation between the phagocytic index and birth weight (g) (R = 0.25, p = 0.003)

Fig. 2

Correlation between the plasma bactericidal activity and gestational age (completed weeks of pregnancy) (R = 0.26, p = 0.002))
Correlation between the plasma bactericidal activity and gestational age (completed weeks of pregnancy) (R = 0.26, p = 0.002))

Comparison of birth weight, PLT and parameters evaluating phagocytic and bactericidal activity of platelets between preterm newborns born near term, between 34 and 36 weeks of pregnancy (study group) and full-term newborns (control group)

Study groupLPNN = 66Control groupFTNN = 74p
Birth weight (g)Me = 2450(Q1 = 2000; Q3 = 2600)Me = 3415(Q1 = 3000; Q3 = 3700)<0.001***
PLT (×103/μL)Me = 225(Q1 = 188; Q3 = 267)Me = 258.5(Q1 = 222; Q3 = 300)0.003**
Percentage of phagocytic plateletsMe = 1.1(Q1 = 1; Q3 = 1.2)Me = 1.1(Q1 = 1; Q3 = 1.2)NS
Phagocytic indexMe = 1(Q1 = 1; Q3 = 1.1)Me = 1(Q1 = 1; Q3 = 1.1)NS
Bactericidal activity of plateletsMe = 0, M = 0.7(Q1 = 0; Q3 = 1.2)Me = 0, M = 0.8(Q1 = 0; Q3 = 1.6)NS
Plasma bactericidal activityMe = 41.6(Q1 = 35,4; Q3 = 45.9)Me = 43.8(Q1 = 38,3; Q3 = 48.4)0.027*
sP-selectin concentration (ng/ml)Me = 63.9(Q1 = 50.8; Q3 = 78)Me = 71(Q1 = 58.4; Q3 = 83.5)0.026*
Interleukin 6 concentration (pg/ml)Me = 3.6(Q1 = 2.9; Q3 = 4.6)Me = 3.9(Q1 = 3.4; Q3 = 4.9)0.02*
DOI: https://doi.org/10.5604/01.3001.0014.6647 | Journal eISSN: 1732-2693
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Language: English
Page range: 18 - 23
Submitted on: Apr 20, 2020
Accepted on: Oct 22, 2020
Published on: Jan 19, 2021
Published by: Hirszfeld Institute of Immunology and Experimental Therapy
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year
Keywords:
platelets,
phagocytosis,
late preterm newborns,
infection
Related subjects:
Life sciences,
Molecular biology,
Microbiology and virology,
Medicine,
Basic medical science,
Immunology

© 2021 Alicja Wasiluk, Barbara Kicel-Wesolowska, Robert Milewski, Joanna Matowicka-Karna, published by Hirszfeld Institute of Immunology and Experimental Therapy
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

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