Figure 1
Figure 2
Perioperative outcomes
| n (%) or mean (standard deviation) | |
|---|---|
| Operative procedure | |
| Posterior sectionectomy | 2 (15) |
| Right/left hepatectomy | 10 (77) |
| Right trisectionectomy | 1 (8) |
| Operative time (min) | 323 (122.9) |
| Estimated blood loss (mL) | 1439 (1372.7) |
| Length of stay (days) | 14 (5.7) |
| Complications | |
| Wound infection | 2 |
| Pleural effusion | 5 |
| Intraabdominal collection | 1 |
| Bile leakage | 1 |
| Pathological results | |
| Resection margins | |
| R0 (free margins) | 10 (77) |
| R1 (microscopically positive) | 3 (23) |
| Tumor differentiation | |
| Moderate | 5 (39) |
| Poor | 8 (62) |
| Satellite nodule positive | 3 (23) |
Patient and tumor characteristics
| Characteristic | n (%) or mean (standard deviation) |
|---|---|
| Age (years) | 51.4 (9.5) |
| Male sex | 12 (92) |
| Underlying liver disease | |
| Hepatitis B virus (HBV) | 7 (54) |
| HBV and hepatitis C virus (HCV) HBV | 2 (15) |
| and hepatitis C infection (HCV) | 4 (31) |
| Non-HBV/HCV | |
| Tumor diameter (cm) | 11.2 (5.9) |
| Child–Pugh A | 13 (100) |
| α-Fetoprotein at diagnosis (IU/mL) | 13615 (41129) |
| Tumor thrombus location | |
| 2nd branch portal vein (PV) | 3 (23) |
| 1st branch PV (right or left PV) | 4 (31) |
| Main PV | 3 (23) |
| Hepatic vein/inferior vena cava | 3 (23) |
Univariate Cox proportional hazards model analysis to identify prognostic factors related to recurrence free and overall survival
| Recurrence free survival | Overall survival | Prognostic factor |
|---|---|---|
| 0.81 (0.20 to 3.25), 0.76 | 0.70 (0.09 to 5.09), 0.72 | Tumor size ≥10 cm |
| 2.07 (0.41 to 10.45), 0.37 | 3.54 (0.50 to 25.28), 0.21 | R0, tumor free resection margin |
| 2.80 (0.56 to 14.02), 0.18 | P, no death of patients without cirrhosis during follow up | Liver cirrhosis |
| 3.62 (0.44 to 30.04), 0.20 | P, no death of patients without preoperative transarterial chemoembolization during follow up | Preop transarterial chemoembolization |