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Prevalence of impaired lower airway function in Thai patients with allergic rhinitis Cover

Prevalence of impaired lower airway function in Thai patients with allergic rhinitis

Open Access
|Jan 2017

Figures & Tables

Figure 1

Study flow chart AR = Allergic rhinitis, CXR = chest x-ray, PNS = film paranasal sinus, FEV1 = force expiratory volume in 1 s.
Study flow chart AR = Allergic rhinitis, CXR = chest x-ray, PNS = film paranasal sinus, FEV1 = force expiratory volume in 1 s.

Prevalence of abnormal pulmonary function (Force expiratory volume in 1 s <80%), duration of allergy, severity of allergic symptoms, and sensitization to allergens

NumberPrevalence (%)
Overall prevalence15323 (15)
Duration of allergy
 ≤ 5 years6210 (16)
 5-10 years527 (14)
 ≥ 10 years396 (15)
Severity of allergic symptoms
 Mild intermittent384 (11)
 Moderate/severe intermittent375 (14)
 Mild persistent192 (11)
 Moderate/severe persistent5912 (20)
Sensitization to indoor allergens251 (4)
Sensitization to outdoor allergens161 (6)
Sensitization to both indoor and outdoor allergens11221 (19)

Clinical characteristics and their relation to percent changes of FEV1

CharacteristicsTotalSubject with percent change FEV1≥ 12%OR95%CIP
Duration of allergy (y)
 ≤ 5620 (0%)--
 5-10523 (5.8%)--0.06
 ≥ 10391 (2.6%)--0.21
Severity of allergic symptoms
 Mild intermittent381 (2.63%)1-
 Moderate/severe intermittent371 (2.7%)1.030.07-15.820.99
 Mild persistent190 (0%)0-0.48
 Moderate/severe persistent592 (3.39%)1.280.12-13.710.83
Sensitization to indoor allergens252 (8%)5.120.75-34.660.06
Sensitization to outdoor allergens160 (0%)000.48
Sensitization to indoor and outdoor allergens1122 (1.79%)0.360.05-2.510.28

Clinical characteristics and their relation to FEV1

CharacteristicsTotalSubject with FEV1 < 80%OR95%CIP
Duration of allergy (y)
 ≤ 56210 (16%)1-
 5-10527 (14%)0.830.34-2.040.691
 ≥ 10396 (15%)0.950.38-2.420.921
Severity of allergic symptoms -
 Mild intermittent384 (11%)1-
 Moderate/severe intermittent375 (14%)1.280.37-4.410.691
 Mild persistent192 (11%)10.20-4.981.000
 Moderate/severe persistent5912 (20%)1.930.67-5.550.203
Sensitization to indoor allergens591 (4%)0.230.08-1.650.09
Sensitization to outdoor allergens161 (6%)0.390.06-2.690.29
Sensitization to indoor and outdoor allergens11221 (19%)7.791.08-55.91

P < 0.05

0.03

Clinical characteristics and their relation to FEF25–75

CharacteristicsTotalParticipant with FEF2–75<80%OR95%CIP
Duration of allergy (y)
 ≤ 56210 (16%)1-
 5-105214 (27%)1.670.81-3.040.16
 ≥ 103913 (33%)2.071.01-4.25

P < 0.05

0.04
Severity of allergic symptoms
 Mild intermittent3810 (26%)1-
 Moderate/severe intermittent379 (24%)0.920.42-2.010.04
 Mild persistent194 (21%)0.800.28-2.210.66
 Moderate/severe persistent5914 (24%)0.900.44-1.810.77
Sensitization to indoor allergens258 (32%)1.410.73-2.710.31
Sensitization to outdoor allergens166 (38%)1.660.82-3.350.19
Sensitization to both indoor and outdoor allergens11223 (21%)0.600.34-1.050.08

Prevalence of abnormal pulmonary function test results

Number (percent)
Abnormal FEV123 (15%)
Abnormal % change of FEV14 (3%)
Abnormal FEF25–7537 (24%)

Patient characteristics

CharacteristicsNumber (percent)
Age (years)
 Mean ± standard deviation34.4 ±10.5 (range 20-59)
Sex
 Male/Female46 (30%)/107 (70%)
Duration of symptoms
 ≤ 5 years62 (41%)
 5-10 years52 (34%)
 ≥ 10 years39 (26%)
Severity of allergic rhinitis
 Mild intermittent38 (25%)
 Moderate/severe intermittent37 (24%)
 Mild persistent19 (12%)
 Moderate/severe persistent59 (39%)
Allergic to indoor allergens25 (16%)
Allergic to outdoors allergens16 (11%)
Allergic to both indoor and outdoor allergens112 (73%)
DOI: https://doi.org/10.5372/1905-7415.1001.467 | Journal eISSN: 1875-855X | Journal ISSN: 1905-7415
Language: English
Page range: 67 - 74
Published on: Jan 31, 2017
Published by: Chulalongkorn University
In partnership with: Paradigm Publishing Services
Publication frequency: 6 issues per year

© 2017 Pongsakorn Tantilipikorn, Jitraporn Juntabenjapat, Torpong Thongngarm, Paraya Assanasen, Chaweewan Bunnag, Bandit Thinkhamrop, published by Chulalongkorn University
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.