References
- 1. Gottesman MM, Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem. 1993;62:385-427.10.1146/annurev.bi.62.070193.002125
- 2. Persidis A. Cancer multidrug resistance. Nat Biotechnol. 1999; 17:94-5.10.1038/5289
- 3. Fojo AT, Ueda K, Slamon DJ, Poplack DG, Gottesman MM, Pastan I. Expression of a multidrug-resistance gene in human tumors and tissues. Proc Natl Acad Sci U S A. 1987; 84:265-9.10.1073/pnas.84.1.265
- 4. Callaghan R, Crowley E, Potter S, Kerr ID. P-glycoprotein: so many ways to turn it on. J Clin Pharmacol. 2008; 48:365-78.10.1177/0091270007311568
- 5. Miller DS, Bauer B, Hartz AM. Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy. Pharmacol Rev. 2008; 60:196-209.10.1124/pr.107.07109
- 6. Sein KK, Maeno Y, Thuc HV, Anh TK, Aikawa M. Differential sequestration of parasitized erythrocytes in the cerebrum and cerebellum in human cerebral malaria. Am J Trop Med Hyg. 1993; 48:504-11.
- 7. Kochar DK, Kumawat BL, Halwai M, Kochar SK, Shubhakaran, Thanvi I. Brainstem auditory evoked potentials and somatosensory evoked potentials in cerebral malaria-a prognostic significance. J Assoc Physicians India. 2000; 48:295-300.
- 8. Chaudhary HR, Meena SR, Jani D, Tiwari U, Goyal RK. Extrapyramidal syndrome in cerebral malaria. J Assoc Physicians India. 1992; 40:347.
- 9. Clark CJ, Phillips RS, Stone TW. Neuropeptidecontaining cells in the cortex and striatum of mice with cerebral malaria. Adv Exp Med Biol. 2003; 527: 347-52.
- 10. Newton CR, Warrell DA. Neurological manifestations of falciparum malaria. Ann Neurol. 1998; 43:695-702.10.1002/ana.410430603
- 11. Berendt AR, Tumer GD, Newbold CI. Cerebral malaria: the sequestration hypothesis. Parasitol Today. 1994; 10:412-4.10.1016/0169-4758(94)90238-0
- 12. Brown H, Turner G, Rogerson S, Tembo M, Mwenechanya J, Molyneux M, et al. Cytokine expression in the brain in human cerebral malaria. J Infect Dis. 1999; 180:1742-6.
- 13. Brown H, Hien TT, Day N, Mai NT, Chuong LV, Chau TT, et al. Evidence of blood-brain barrier dysfunction in human cerebral malaria. Neuropathol Appl Neurobiol. 1999; 25:331-40.10.1046/j.1365-2990.1999.00188.x
- 14. Abbott NJ, Hughes CC, Revest PA, Greenwood J. Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier. J Cell Sci. 1992; 103:23-37.
- 15. Hong H, Lu Y, Ji ZN, Liu GQ. Up-regulation of P-glycoprotein expression by glutathione depletioninduced oxidative stress in rat brain microvessel endothelial cells. J Neurochem. 2006; 98:1465-73.10.1111/j.1471-4159.2006.03993.x
- 16. Dorovini-Zis K, Schmidt K, Huynh H, Fu W, Whitten RO, Milner D, et al. The neuropathology of fatal cerebral malaria in Malawian children. Am J Pathol. 2011; 178:2146-58.
- 17. Idro R, Kakooza-Mwesige A, Balyejjussa S, Mirembe G, Mugasha C, Tugumisirize J, et al. Severe neurological sequelae and behaviour problems after cerebral malaria in Ugandan children. BMC Res Notes. 2010; 3:104.10.1186/1756-0500-3-104
- 18. Kooij G, van Horssen J, de Lange EC, Reijerkerk A, van der Pol SM, van Het Hof B, et al. T lymphocytes impair P-glycoprotein function during neuroinflammation. J Autoimmun. 2010; 34:416-25.10.1016/j.jaut.2009.10.006
- 19. McRae MP, Brouwer KL, Kashuba AD. Cytokine regulation of P-glycoprotein. Drug Metab Rev. 2003; 35:19-33.10.1081/DMR-120018247
- 20. Goralski KB, Hartmann G, Piquette-Miller M, Renton KW. Downregulation of mdr1a expression in the brain and liver during CNS inflammation alters the in vivo disposition of digoxin. Br J Pharmacol. 2003; 139: 35-48.
- 21. Zhao YL, Du J, Kanazawa H, Sugawara A, Takagi K, Kitaichi K, et al. Effect of endotoxin on doxorubicin transport across blood-brain barrier and Pglycoprotein function in mice. Eur J Pharmacol. 2002; 445:115-23.
- 22. Tan KH, Purcell WM, Heales SJ, McLeod JD, Hurst RD. Evaluation of the role of P-glycoprotein in inflammation induced blood-brain barrier damage. Neuroreport. 2002; 13:2593-7.10.1097/00001756-200212200-00042
- 23. Theron D, Barraud de Lagerie S, Tardivel S, Pelerin H, Demeuse P, Mercier C, et al. Influence of tumor necrosis factor-á on the expression and function of P-glycoprotein in an immortalised rat brain capillary endothelial cell line, GPNT. Biochem Pharmacol. 2003; 66:579-87.10.1016/S0006-2952(03)00340-X
- 24. Walther W, Stein U. Influence of cytokines on mdr1 expression in human colon carcinoma cell lines: increased cytotoxicity of MDR relevant drugs. J Cancer Res Clin Oncol. 1994; 120:471-8.10.1007/BF01191800
- 25. Yu C, Kastin AJ, Tu H, Waters S, Pan W. TNF activates P-glycoprotein in cerebral microvascular endothelial cells. Cell Physiol Biochem. 2007; 20:853-8.10.1159/000110445
- 26. Kooij G, Backer R, Koning JJ, Reijerkerk A, van Horssen J, van der Pol SM, et al. P-glycoprotein acts as an immunomodulator during neuroinflammation. PLoS One. 2009; 4:e8212. 10.1371/journal.pone.0008212