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Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a ‘‘Pure Motor Restless Legs Syndrome’’? Cover

Movements Mimicking Myoclonus Associated with Spinal Cord Pathology: Is this a ‘‘Pure Motor Restless Legs Syndrome’’?

By: William G. Ondo  
Open Access
|Mar 2012

Abstract

Background: The neuroanatomic substrate of restless legs syndrome (RLS) is poorly understood, and the diagnosis is clinically made based upon subjective sensory symptoms, although a motor component is usually present.

Case Report: We report two cases of elderly patients with spinal pathology who were referred by neurologists for myoclonus. Both had semi-rhythmic leg movements that partially improved while standing, but denied any urge to move. These movements improved dramatically with pramipexole, a dopamine agonist used for RLS.

Discussion: We propose that this ‘‘myoclonus’’ is actually the isolated stereotypic motor component of RLS.

DOI: https://doi.org/10.5334/tohm.99 | Journal eISSN: 2160-8288
Language: English
Submitted on: May 8, 2011
Accepted on: Jun 23, 2011
Published on: Mar 20, 2012
Published by: Columbia University Libraries/Information Services
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2012 William G. Ondo, published by Columbia University Libraries/Information Services
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.