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Potential of Individual Upper-Limb Muscles to Contribute to Postural Tremor: Simulations From Neural Drive to Joint Rotation Cover

Potential of Individual Upper-Limb Muscles to Contribute to Postural Tremor: Simulations From Neural Drive to Joint Rotation

Open Access
|Feb 2025

References

  1. 1Schneider SA, Deuschl G. The Treatment of Tremor. Neurotherapeutics. 2014; 11(1): 128138. DOI: 10.1007/s13311-013-0230-5
  2. 2Louis ED, Ferreira JJ. How Common Is the Most Common Adult Movement Disorder? Update on the Worldwide Prevalence of Essential Tremor. Movement Disorders, Apr 2010. 25(5): 534541. DOI: 10.1002/mds.22838
  3. 3Bhatia KP, et al. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Movement Disorders. 2018; 33(1): 7587. DOI: 10.1002/mds.27121
  4. 4Louis ED, Ottman R. How many people in the USA have essential tremor? Deriving a population estimate based on epidemiological data. Tremor and other hyperkinetic movements (New York, N.Y.). 2014; 4: 259. DOI: 10.5334/tohm.198
  5. 5Koller WC. Pharmacologic treatment of parkinsonian tremor. Archives of neurology. 1986; 43(2): 126127. DOI: 10.1001/archneur.1986.00520020020009
  6. 6Elble R, Deuschl G. Milestones in tremor research. Movement Disorders. 2011; 26(6): 10961105. DOI: 10.1002/mds.23579
  7. 7Diaz NL, Louis ED. Survey of medication usage patterns among essential tremor patients: Movement disorder specialists vs. general neurologists. 2010; 16: 604607. DOI: 10.1016/j.parkreldis.2010.07.011
  8. 8Flora ED, Perera CL, Cameron AL, Maddern GJ. Deep brain stimulation for essential tremor: a systematic review. Movement disorders. 2010; 25(11): 15501559. DOI: 10.1002/mds.23195
  9. 9Wharen Jr RE, et al. Thalamic DBS with a constant-current device in essential tremor: a controlled clinical trial. Parkinsonism & related disorders. 2017; 40: 1826. DOI: 10.1016/j.parkreldis.2017.03.017
  10. 10Dembek TA, et al. Probabilistic mapping of deep brain stimulation effects in essential tremor. NeuroImage: Clinical. 2017; 13: 164173. DOI: 10.1016/j.nicl.2016.11.019
  11. 11Pahwa R, et al. Long-term evaluation of deep brain stimulation of the thalamus. Journal of neurosurgery. 2006; 104(4): 506512. DOI: 10.3171/jns.2006.104.4.506
  12. 12Blomstedt P, Hariz MI. Are complications less common in deep brain stimulation than in ablative procedures for movement disorders?. Stereotactic and functional neurosurgery. 2006; 84(2–3): 7281. DOI: 10.1159/000094035
  13. 13Shih LC, LaFaver K, Lim C, Papavassiliou E, Tarsy D. Loss of benefit in VIM thalamic deep brain stimulation (DBS) for essential tremor (ET): how prevalent is it?. Parkinsonism & Related Disorders. 2013; 19(7): 676679. DOI: 10.1016/j.parkreldis.2013.03.006
  14. 14Kestenbaum M, Ford B, Louis ED. Estimating the Proportion of Essential Tremor and Parkinson’s Disease Patients Undergoing Deep Brain Stimulation Surgery: Five-Year Data From Columbia University Medical Center (2009–2014). Movement Disorders Clinical Practice. 2015; 2(4): 384387. DOI: 10.1002/mdc3.12185
  15. 15Louis ED, Rohl B, Rice C. Defining the Treatment Gap: What Essential Tremor Patients Want That They Are Not Getting. Tremor and other hyperkinetic movements (New York, N.Y.). 2015; 5: 331. DOI: 10.5334/tohm.239
  16. 16Kotovsky J, Rosen MJ. A wearable tremor-suppression orthosis. J Rehabil Res Dev. 1998; 35(4): 373387. [Online].
  17. 17Hashemi SM, Golnaraghi MF, Patla AE. Tuned vibration absorber for suppression of rest tremor in Parkinson’s disease. Med. Biol. Eng. Comput. Jan 2004; 42(1): 6170. DOI: 10.1007/BF02351012
  18. 18Belda-Lois JM, et al. Controllable mechanical tremor reduction. Assessment of two orthoses. Technology & Disability. 2007; 19(4): 169178 [Online]. DOI: 10.3233/TAD-2007-19402
  19. 19Loureiro RCV, Belda-Lois JM, Lima ER, Pons JL, Sanchez-Lacuesta JJ, Harwin WS. Upper limb tremor suppression in ADL via an orthosis incorporating a controllable double viscous beam actuator. In: International Conference on Rehabilitation Robotics (ICORR). 28 June–1 July 2005. pp. 119122. DOI: 10.1109/ICORR.2005.1501065
  20. 20Case D, Taheri B, Richer E. A Lumped-Parameter Model for Adaptive Dynamic MR Damper Control. Ieee-Asme T Mech. Aug 2015; 20(4): 16891696. DOI: 10.1109/TMECH.2014.2347898
  21. 21Case D, Taheri B, Richer E. Dynamical Modeling and Experimental Study of a Small-Scale Magnetorheological Damper. Ieee-Asme T Mech. Jun 2014; 19(3): 10151024. DOI: 10.1109/TMECH.2013.2265701
  22. 22Case D, Taheri B, Richer E. Design and Characterization of a Small-Scale Magnetorheological Damper for Tremor Suppression. Ieee-Asme T Mech. Feb 2013; 18(1): 96103. DOI: 10.1109/TMECH.2011.2151204
  23. 23Belda-Lois JM, Page A, Baydal-Bertomeu JM, Poveda R, Barbera R. Biomechanical constraints in the design of robotic systems for tremor suppression. In: Rehabilitation Robotics, Kommu SS, editors. Vienna, Austria: Itech Education and Publishing; 2007. DOI: 10.5772/5152
  24. 24Dosen S, et al. Online Tremor Suppression Using Electromyography and Low-Level Electrical Stimulation. Ieee T Neur Sys Reh. May 2015. 23(3): 385395. DOI: 10.1109/TNSRE.2014.2328296
  25. 25Freeman CT, Sampson P, Burridge JH, Hughes AM. Repetitive control of functional electrical stimulation for induced tremor suppression. (in English), Mechatronics. Dec 2015; 32: 7987. DOI: 10.1016/j.mechatronics.2015.10.008
  26. 26Maneski LP, et al. Electrical stimulation for the suppression of pathological tremor. (in English), Med. Biol. Eng. Comput. Oct 2011; 49(10): 11871193. DOI: 10.1007/s11517-011-0803-6
  27. 27Prochazka A, Elek J, Javidan M. Attenuation of pathological tremors by functional electrical-stimulation I. Method. Annals of Biomedical Engineering. 1992; 20(2): 205224. DOI: 10.1007/BF02368521
  28. 28Samotus O, Kumar N, Rizek P, Jog M. Botulinum Toxin Type A Injections as Monotherapy for Upper Limb Essential Tremor Using Kinematics. Can. J. Neurol. Sci. Jan 2018; 45(1): 1122. DOI: 10.1017/cjn.2017.260
  29. 29Samotus O, Lee J, Jog M. Long-term tremor therapy for Parkinson and essential tremor with sensor-guided botulinum toxin type A injections. Plos One. Jun 2017; 12(6): Art no. e0178670. DOI: 10.1371/journal.pone.0178670
  30. 30Samotus O, Rahimi F, Lee J, Jog M. Functional Ability Improved in Essential Tremor by IncobotulinumtoxinA Injections Using Kinematically Determined Biomechanical Patterns – A New Future. Plos One. Apr 2016; 11(4): Art no. e0153739. DOI: 10.1371/journal.pone.0153739
  31. 31Rahimi F, Samotus O, Lee J, Jog M. Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns. Tremor and Other Hyperkinetic Movements. 2015; 5. DOI: 10.5334/tohm.240
  32. 32Heo JH, et al. Suppression of action tremor by sensory electrical stimulation in patients with Essential Tremor. Journal of Mechanics in Medicine and Biology. Dec 2016. 16(8): Art no. 1640026. DOI: 10.1142/S0219519416400261
  33. 33Heo JH, et al. Sensory electrical stimulation for suppression of postural tremor in patients with essential tremor. (in eng), Biomed Mater Eng. 2015; 26(Suppl 1): S8039. DOI: 10.3233/BME-151372
  34. 34Dideriksen JL, et al. Electrical Stimulation of Afferent Pathways for the Suppression of Pathological Tremor. (in eng), Front Neurosci. 2017; 11: 178. DOI: 10.3389/fnins.2017.00178
  35. 35Lin PT, et al. Noninvasive Neuromodulation in Essential Tremor Demonstrates Relief in a Sham-Controlled Pilot Trial. Movement Disorders. Jul 2018. 33(7): 11821183. DOI: 10.1002/mds.27350
  36. 36Pahwa R, et al. An Acute Randomized Controlled Trial of Noninvasive Peripheral Nerve Stimulation in Essential Tremor. Neuromodulation. Jul 2019. 22(5): 537545. DOI: 10.1111/ner.12930
  37. 37Wagle Shukla A. Rationale and Evidence for Peripheral Nerve Stimulation for Treating Essential Tremor. (in eng), Tremor and other hyperkinetic movements (New York, N.Y.). 2022; 12: 20. DOI: 10.5334/tohm.685
  38. 38Corie TH, Charles SK. Simulated Tremor Propagation in the Upper Limb: From Muscle Activity to Joint Displacement. Journal of Biomechanical Engineering. 2019; 141(8): 081001. DOI: 10.1115/1.4043442
  39. 39Davidson AD, Charles SK. Fundamental Principles of Tremor Propagation in the Upper Limb. Annals of Biomedical Engineering. 2017; 45(4): 11331147. DOI: 10.1007/s10439-016-1765-5
  40. 40He, F, et al. Nonlinear interactions in the thalamocortical loop in essential tremor: A model-based frequency domain analysis. 2016; 324: 377389. DOI: 10.1016/j.neuroscience.2016.03.028
  41. 41Matsumoto Y, et al. Analysis of EMG signals of patients with essential tremor focusing on the change of tremor frequency. In 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2012, no. Conference Proceedings, pp. 22442250, [Online]. Available: https://ieeexplore.ieee.org/stampPDF/getPDF.jsp?tp=&arnumber=6346409&ref=. DOI: 10.1109/EMBC.2012.6346409
  42. 42Nisticò R, et al. Synchronous pattern distinguishes resting tremor associated with essential tremor from rest tremor of Parkinson’s disease. 2011; 17: 3033. DOI: 10.1016/j.parkreldis.2010.10.006
  43. 43Winter DA. Biomechanics and motor control of human movement, 3rd ed. Hoboken, NJ: John Wiley & Sons; 2005. pp. xvi, 325 p.
  44. 44Rozendaal LA. Stability of the shoulder: intrinsic muscle properties and reflexive control; 1997.
  45. 45Van der Helm FC, Rozendaal LA. Musculoskeletal systems with intrinsic and proprioceptive feedback. In Biomechanics and neural control of posture and movement: Springer; 2000. 164174. DOI: 10.1007/978-1-4612-2104-3_11
  46. 46Winters JM, Stark L. Estimated mechanical properties of synergistic muscles involved in movements of a variety of human joints. Journal of biomechanics. 1988; 21(12): 10271041. DOI: 10.1016/0021-9290(88)90249-7
  47. 47Saul KR, et al. Benchmarking of dynamic simulation predictions in two software platforms using an upper limb musculoskeletal model. Computer methods in biomechanics and biomedical engineering. 2015; 18(13): 14451458. DOI: 10.1080/10255842.2014.916698
  48. 48Holzbaur KRS, Murray WM, Gold GE, Delp SL. Upper limb muscle volumes in adult subjects. 2007; 40: 742749. DOI: 10.1016/j.jbiomech.2006.11.011
  49. 49Holzbaur KRS, Delp SL, Gold GE, Murray WM. Moment-generating capacity of upper limb muscles in healthy adults. Journal of Biomechanics. 2006; 40(11): 24422449. DOI: 10.1016/j.jbiomech.2006.11.013
  50. 50Holzbaur KRS, Murray WM, Delp SL. A model of the upper extremity for simulating musculoskeletal surgery and analyzing neuromuscular control. Annals of Biomedical Engineering. Jun 2005; 33(6): 829840. DOI: 10.1007/s10439-005-3320-7
  51. 51Fryar CD, Carroll MD, Gu Q, Afful J, Ogden CL. Anthropometric reference data for children and adults: United States, 2015–2018. Vital and Health Statistics. 2021; 3(46): 715.
  52. 52De Leva P. Adjustments to Zatsiorsky-Seluyanov’s segment inertia parameters. J biomech. 1996; 29(9): 12231230. DOI: 10.1016/0021-9290(95)00178-6
  53. 53Drake WB, Charles SK. Passive Stiffness of Coupled Wrist and Forearm Rotations. Annals of Biomedical Engineering. 2014; 42(9): 18531866. DOI: 10.1007/s10439-014-1054-0
  54. 54Formica D, Charles SK, Zollo L, Guglielmelli E, Hogan N, Krebs HI. The passive stiffness of the wrist and forearm. Journal of neurophysiology. 2012; 108(4): 11581166. DOI: 10.1152/jn.01014.2011
  55. 55Pando AL, Lee H, Drake WB, Hogan N, Charles SK. Position-Dependent Characterization of Passive Wrist Stiffness. 2014; 61: 22352244. DOI: 10.1109/TBME.2014.2313532
  56. 56Corke P. 2nd ed. Robotics, Vision and Control: Fundamental Algorithms In MATLAB® Second, Completely Revised, Extended And Updated Edition. Cham: Springer International Publishing; 2017. 693. DOI: 10.1007/978-3-319-54413-7
  57. 57Palm WJ. System dynamics. McGraw-Hill Science New York; 2014.
  58. 58Puttaraksa G, et al. Voluntary and tremorogenic inputs to motor neuron pools of agonist/antagonist muscles in essential tremor patients. (in eng), J Neurophysiol. 2019; 122(5): 20432053. DOI: 10.1152/jn.00407.2019
  59. 59Burdet EF. David; Milner, Theodore, Human Robotics: Neuromechanics and Motor Control. Cambridge, MA: The MIT Press; 2013. DOI: 10.7551/mitpress/9007.001.0001
  60. 60Perreault EJ, Kirsch RF, Crago PE. Multijoint dynamics and postural stability of the human arm. Experimental brain research. 2004; 157(4): 507517. DOI: 10.1007/s00221-004-1864-7
  61. 61De Serres SJ, Milner TE. Wrist muscle activation patterns and stiffness associated with stable and unstable mechanical loads. Exp Brain Res. 1991; 86(2): 4518. DOI: 10.1007/BF00228972
  62. 62Milner TE, Cloutier C. Compensation for mechanically unstable loading in voluntary wrist movement. Exp Brain Res. 1993; 94(3): 52232. DOI: 10.1007/BF00230210
  63. 63Milner TE, Cloutier C. Damping of the wrist joint during voluntary movement. Exp Brain Res. Oct 1998; 122(3): 30917. DOI: 10.1007/s002210050519
  64. 64Halaki M, O’Dwyer N, Cathers I. Systematic nonlinear relations between displacement amplitude and joint mechanics at the human wrist. J Biomech. 2006; 39(12): 217182. DOI: 10.1016/j.jbiomech.2005.06.022
  65. 65de Vlugt E, van Eesbeek S, Baines P, Hilte J, Meskers CG, de Groot JH. Short range stiffness elastic limit depends on joint velocity. J Biomech. Jul 28 2011; 44(11): 210612. DOI: 10.1016/j.jbiomech.2011.05.022
  66. 66Klomp A, de Groot JH, de Vlugt E, Meskers CG, Arendzen JH, van der Helm FC. Perturbation amplitude affects linearly estimated neuromechanical wrist joint properties. IEEE Trans Biomed Eng. Apr 2014; 61(4): 100514. DOI: 10.1109/TBME.2013.2290022
  67. 67Fromme NP, Camenzind M, Riener R, Rossi RM. Need for mechanically and ergonomically enhanced tremor-suppression orthoses for the upper limb: a systematic review. J Neuroeng Rehabil. 2019/07/18 2019; 16(1): 93. DOI: 10.1186/s12984-019-0543-7
  68. 68O’Connor RJ, Kini MU. Non-pharmacological and non-surgical interventions for tremor: A systematic review. Parkinsonism & Related Disorders. Aug 2011; 17(7): 509515. DOI: 10.1016/j.parkreldis.2010.12.016
  69. 69Mo J, Priefer R. Medical Devices for Tremor Suppression: Current Status and Future Directions. Biosensors. 03/30 2021; 11: 99. DOI: 10.3390/bios11040099
  70. 70Charles SK, Hogan N. Dynamics of wrist rotations. J Biomech. 2011; 44(4): 614621. DOI: 10.1016/j.jbiomech.2010.11.016
  71. 71Louis ED. Essential tremor: a nuanced approach to the clinical features. (in eng), Pract Neurol. Oct 2019; 19(5): 389398. DOI: 10.1136/practneurol-2018-002183
  72. 72Syndergaard I, Free D, Farina D, Charles SK. The effect of afferent feedback on tremor propagation: a modeling study. In Society for Neuroscience. San Diego, CA; 2022.
  73. 73Standring DJ, et al. Distribution of tremorogenic activity among the major superficial muscles of the upper limb in persons with Essential tremor. Clinical Neurophysiology. 2022/10/01/ 2022. 142: 2032. DOI: 10.1016/j.clinph.2022.07.001
  74. 74Free DB, et al. Essential Tremor accentuates the pattern of tremor-band coherence between upper-limb muscles. (in eng), J Neurophysiol. Jan 25 2023; 129(3): 52440. DOI: 10.1152/jn.00398.2022
  75. 75Elble R, et al. Reliability of a new scale for essential tremor. Mov Disord, Oct 2012; 27(12): 15679. DOI: 10.1002/mds.25162
  76. 76Pigg AC, et al. Distribution of tremor among the major degrees of freedom of the upper limb in subjects with Essential Tremor. Clinical Neurophysiology. 2020/11/01/ 2020. 131(11): 27002712. DOI: 10.1016/j.clinph.2020.08.010
  77. 77Plesha M, Gray G, Costanzo F. Engineering Mechanics: Statics, 2nd ed. New York, NY: McGraw Hill; 2013.
DOI: https://doi.org/10.5334/tohm.949 | Journal eISSN: 2160-8288
Language: English
Submitted on: Aug 28, 2024
Accepted on: Feb 1, 2025
Published on: Feb 25, 2025
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2025 Spencer A. Baker, Landon J. Beutler, Daniel B. Free, Dario Farina, Steven K. Charles, published by Ubiquity Press
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