References
- Comfort A. Neuromythology? Nature. 1971; 229: 282. DOI: 10.1038/229282b0
- Landau WM. Clinical neuromythology. I. The Marcus Gunn phenomenon: loose canon of neuro-ophthalmology. Neurology. 1988; 38: 1141–1142. DOI: 10.1212/WNL.38.7.1141
- Landau WM. Clinical neuromythology VII. Artificial intelligence: the brain transplant cure for parkinsonism. Neurology. 1990; 40: 733–740. DOI: 10.1212/WNL.40.5.733
- Tyler KL, Ruegg S. The neuromythology of Hashimoto encephalopathy: The emperor has no clothes. Neurology. 2020; 94: 55–56. DOI: 10.1212/WNL.0000000000008776
- Elias WJ, Shah BB. Essential Tremor. JAMA. 2024; 332: 418–419. DOI: 10.1001/jama.2024.7475
- Louis ED, Benito-Leon J, Ottman R, Bermejo-Pareja F. A population-based study of mortality in essential tremor. Neurology. 2007; 69: 1982–1989. DOI: 10.1212/01.wnl.0000279339.87987.d7
- Minor L. Uber hereditaren tremor. Abl Ges Neurol Psychiatr. 1922; 28: 514–516.
- Jankovic J, Beach J, Schwartz K, Contant C. Tremor and longevity in relatives of patients with Parkinson’s disease, essential tremor, and control subjects. Neurology. 1995; 45: 645–648. DOI: 10.1212/WNL.45.4.645
- Rajput AH, Offord KP, Beard CM, Kurland LT. Essential tremor in Rochester, Minnesota: a 45-year study. J Neurol Neurosurg Psychiatry. 1984; 47: 466–470. DOI: 10.1136/jnnp.47.5.466
- Benito-Leon J, Bermejo-Pareja F, Louis ED. Incidence of essential tremor in three elderly populations of central Spain. Neurology. 2005; 64: 1721–1725. DOI: 10.1212/01.WNL.0000161852.70374.01
- Louis ED, Agnew A, Gillman A, Gerbin M, Viner AS. Estimating annual rate of decline: prospective, longitudinal data on arm tremor severity in two groups of essential tremor cases. J Neurol Neurosurg Psychiatry. 2011; 82: 761–765. DOI: 10.1136/jnnp.2010.229740
- Louis ED, Barnes L, Albert SM, et al. Correlates of functional disability in essential tremor. Mov Disord. 2001; 16: 914–920. DOI: 10.1002/mds.1184
- Louis ED, Rao AK. Functional Aspects of Gait in Essential Tremor: A Comparison with Age-Matched Parkinson’s Disease Cases, Dystonia Cases, and Controls. Tremor Other Hyperkinet Mov (N Y). 2015; 5. DOI: 10.5334/tohm.242
- Louis ED, Berry D, Ghanem A, Cosentino SA. Conversion Rate of Essential Tremor to Essential Tremor Parkinson Disease: Data From a Prospective Longitudinal Study. Neurol Clin Pract. 2023; 13:
e200162 . DOI: 10.1212/CPJ.0000000000200162 - Louis ED, Martuscello RT, Gionco JT, et al. Histopathology of the cerebellar cortex in essential tremor and other neurodegenerative motor disorders: comparative analysis of 320 brains. Acta Neuropathol. 2023; 145: 265–283. DOI: 10.1007/s00401-022-02535-z
- Zubair A, Cersonsky TEK, Kellner S, Huey ED, Cosentino S, Louis ED. What Predicts Mortality in Essential Tremor? A Prospective, Longitudinal Study of Elders. Front Neurol. 2018; 9: 1077. DOI: 10.3389/fneur.2018.01077
- Kamble N, Pal PK. Tremor syndromes: A review. Neurol India. 2018; 66: S36–S47. DOI: 10.4103/0028-3886.226440
- Louis ED, Vonsattel JP, Honig LS, Ross GW, Lyons KE, Pahwa R. Neuropathologic findings in essential tremor. Neurology. 2006; 66: 1756–1759. DOI: 10.1212/01.wnl.0000218162.80315.b9
- Louis ED, Iglesias-Hernandez D, Hernandez NC, et al. Characterizing Lewy Pathology in 231 Essential Tremor Brains From the Essential Tremor Centralized Brain Repository. J Neuropathol Exp Neurol. 2022; 81: 796–806. DOI: 10.1093/jnen/nlac068
- Louis ED, Faust PL. Essential tremor pathology: neurodegeneration and reorganization of neuronal connections. Nat Rev Neurol. 2020; 16: 69–83. DOI: 10.1038/s41582-019-0302-1
- Okelberry T, Lyons KE, Pahwa R. Updates in essential tremor. Parkinsonism Relat Disord. 2024; 122: 106086. DOI: 10.1016/j.parkreldis.2024.106086
- Fanning A, Kuo SH. Clinical Heterogeneity of Essential Tremor: Understanding Neural Substrates of Action Tremor Subtypes. Cerebellum; 2023. DOI: 10.1007/s12311-023-01551-3
- Haubenberger D, Hallett M. Essential Tremor. N Engl J Med. 2018; 379: 596–597. DOI: 10.1056/NEJMcp1707928
- Handforth A, Lang EJ. Increased Purkinje Cell Complex Spike and Deep Cerebellar Nucleus Synchrony as a Potential Basis for Syndromic Essential Tremor. A Review and Synthesis of the Literature. Cerebellum. 2021; 20: 266–281. DOI: 10.1007/s12311-020-01197-5
- Ibrahim MF, Beevis JC, Empson RM. Essential Tremor – A Cerebellar Driven Disorder? Neuroscience. 2021; 462: 262–273. DOI: 10.1016/j.neuroscience.2020.11.002
- Louis ED, Lenka A. The Olivary Hypothesis of Essential Tremor: Time to Lay this Model to Rest? Tremor Other Hyperkinet Mov (N Y). 2017; 7: 473. DOI: 10.5334/tohm.380
- Louis ED. The Essential Tremors: Evolving Concepts of a Family of Diseases. Front Neurol. 2021; 12: 650601. DOI: 10.3389/fneur.2021.650601
- Louis ED. ‘Essential tremor’ or ‘the essential tremors’: is this one disease or a family of diseases? Neuroepidemiology. 2014; 42: 81–89. DOI: 10.1159/000356351
- Faust PL. Is essential tremor a degenerative disorder or an electric disorder? Degenerative disorder. Int Rev Neurobiol. 2022; 163: 65–101. DOI: 10.1016/bs.irn.2022.02.003
- Louis ED, Honig LS, Vonsattel JP, Maraganore DM, Borden S, Moskowitz CB. Essential tremor associated with focal nonnigral Lewy bodies: a clinicopathologic study. Arch Neurol. 2005; 62: 1004–1007. DOI: 10.1001/archneur.62.6.1004
- Louis ED, Vonsattel JP, Honig LS, et al. Essential tremor associated with pathologic changes in the cerebellum. Arch Neurol. 2006; 63: 1189–1193. DOI: 10.1001/archneur.63.8.1189
- Louis ED, Faust PL. Essential Tremor Within the Broader Context of Other Forms of Cerebellar Degeneration. Cerebellum; 2020. DOI: 10.1007/978-3-319-97911-3_99-2
- Mavroudis I, Petridis F, Kazis D. Neuroimaging and neuropathological findings in essential tremor. Acta Neurol Scand. 2019; 139: 491–496. DOI: 10.1111/ane.13101
- Mavroudis I, Kazis D, Petridis F, et al. Morphological and morphometric changes in the Purkinje cells of patients with essential tremor. Exp Ther Med. 2022; 23: 167. DOI: 10.3892/etm.2021.11090
- Paris-Robidas S, Brochu E, Sintes M, et al. Defective dentate nucleus GABA receptors in essential tremor. Brain. 2012; 135: 105–116. DOI: 10.1093/brain/awr301
- Delay C, Tremblay C, Brochu E, et al. Increased LINGO1 in the cerebellum of essential tremor patients. Mov Disord. 2014; 29: 1637–1647. DOI: 10.1002/mds.25819
- Louis ED, Lee M, Cortes E, Vonsattel JP, Faust PL. Matching asymmetry of tremor with asymmetry of postmortem cerebellar hemispheric changes in essential tremor. Cerebellum. 2014; 13: 462–470. DOI: 10.1007/s12311-014-0560-9
- Faust PL, McCreary M, Musacchio JB, Kuo SH, Vonsattel JG, Louis ED. Pathologically based criteria to distinguish essential tremor from controls: analyses of the human cerebellum. Ann Clin Transl Neurol. 2024; 11: 1514–1525. DOI: 10.1002/acn3.52068
- Symanski C, Shill HA, Dugger B, et al. Essential tremor is not associated with cerebellar Purkinje cell loss. Mov Disord; 2014. DOI: 10.1002/mds.25845
- Louis ED, Faust PL. Purkinje cell loss in essential tremor. Mov Disord. 2014; 29: 1329–1330. DOI: 10.1002/mds.25965
- Choe M, Cortes E, Vonsattel JG, Kuo SH, Faust PL, Louis ED. Purkinje cell loss in essential tremor: Random sampling quantification and nearest neighbor analysis. Mov Disord. 2016. DOI: 10.1002/mds.26490
- Louis ED, Faust PL. Prevalence of Lewy pathology in essential tremor is twice as high as expected: A plausible explanation for the enhanced risk for Parkinson disease seen in essential tremor cases. J Neuropathol Exp Neurol. 2023; 82: 454–455. DOI: 10.1093/jnen/nlad021
- Kosmowska B, Wardas J. The Pathophysiology and Treatment of Essential Tremor: The Role of Adenosine and Dopamine Receptors in Animal Models. Biomolecules. 2021; 11. DOI: 10.3390/biom11121813
- Jameel A, Akgun S, Yousif N, et al. The evolution of ventral intermediate nucleus targeting in MRI-guided focused ultrasound thalamotomy for essential tremor: an international multi-center evaluation. Front Neurol. 2024; 15: 1345873. DOI: 10.3389/fneur.2024.1345873
- McGurrin P, Norato G, Thompson-Westra J, et al. Objective response to ethanol in essential tremor: results from a standardized ethanol challenge study. Ann Clin Transl Neurol. 2024; 11: 156–168. DOI: 10.1002/acn3.51943
- Chi W, Wu M, Wang HL, et al. Han family with essential tremor caused by the P421L variant of the TENM4 gene in China. Neurol Sci. 2023; 44: 2003–2015. DOI: 10.1007/s10072-023-06603-4
- Siokas V, Aloizou AM, Tsouris Z, et al. Genetic Risk Factors for Essential Tremor: A Review. Tremor Other Hyperkinet Mov (N Y). 2020; 10: 4. DOI: 10.5334/tohm.67
- Deng H, Wu S, Jankovic J. Essential tremor: genetic update. Expert Rev Mol Med. 2019; 21:
e8 . DOI: 10.1017/erm.2019.7 - Brennan KC, Jurewicz EC, Ford B, Pullman SL, Louis ED. Is essential tremor predominantly a kinetic or a postural tremor? A clinical and electrophysiological study. Mov Disord. 2002; 17: 313–316. DOI: 10.1002/mds.10003
- Louis ED. The primary type of tremor in essential tremor is kinetic rather than postural: cross-sectional observation of tremor phenomenology in 369 cases. Eur J Neurol. 2013; 20: 725–727. DOI: 10.1111/j.1468-1331.2012.03855.x
- Angelini L, Paparella G, Bologna M. Distinguishing essential tremor from Parkinson’s disease: clinical and experimental tools. Expert Rev Neurother. 2024; 24: 799–814. DOI: 10.1080/14737175.2024.2372339
- Zakin E, Simpson D. Botulinum Toxin in Management of Limb Tremor. Toxins (Basel). 2017; 9. DOI: 10.3390/toxins9110365
- Ramirez-Zamora A, Boggs H, Pilitsis JG. Reduction in DBS frequency improves balance difficulties after thalamic DBS for essential tremor. J Neurol Sci. 2016; 367: 122–127. DOI: 10.1016/j.jns.2016.06.001
- Asif M, Mocanu ID, Abdullah U, et al. A novel missense variant of SCN4A co-segregates with congenital essential tremor in a consanguineous Kurdish family. Am J Med Genet A. 2022; 188: 1251–1258. DOI: 10.1002/ajmg.a.62610
- Wolters A, Benecke R. Diagnosis and treatment of tremor in Parkinson’s disease and essential tremor. MMW Fortschr Med. 2007; 149(Suppl 2): 94–96.
- Gungen BD, Aras YG, Gul SS, Acar T, Acar BA, Can NU. How childhood trauma and emotions influence essential tremor and its severity in Sakarya Province. Eur Rev Med Pharmacol Sci. 2022; 26: 2721–2726.
- Lewis S, Liddle J. Diagnosing non-parkinson’s movement disorders. Practitioner. 2012; 256: 21–24, 23.
- Louis ED, Wendt KJ, Pullman SL, Ford B. Is essential tremor symmetric? Observational data from a community-based study of essential tremor. Arch Neurol. 1998; 55: 1553–1559. DOI: 10.1001/archneur.55.12.1553
- Louis ED, Ford B, Wendt KJ, Lee H, Andrews H. A comparison of different bedside tests for essential tremor. Mov Disord. 1999; 14: 462–467. DOI: 10.1002/1531-8257(199905)14:3<;462::AID-MDS1012>3.0.CO;2-V
- Dogu O, Louis ED, Sevim S, Kaleagasi H, Aral M. Clinical characteristics of essential tremor in Mersin, Turkey--a population-based door-to-door study. J Neurol. 2005; 252: 570–574. DOI: 10.1007/s00415-005-0700-8
- Louis ED, Bares M, Benito-Leon J, et al. Essential tremor-plus: a controversial new concept. Lancet Neurol. 2020; 19: 266–270. DOI: 10.1016/S1474-4422(19)30398-9
- Gilmour GS, Martino D, Hunka K, Lawrence P, Kiss ZHT, Bruno V. Response to Thalamic Ventralis Intermedius Nucleus Deep Brain Stimulation in Essential Tremor vs. Essential Tremor-Plus. Front Neurol. 2021; 12: 790027. DOI: 10.3389/fneur.2021.790027
- Yu CH, Lench DH, Cooper C, Rowland NC, Takacs I, Revuelta G. Deep brain stimulation for essential tremor versus essential tremor plus: should we target the same spot in the thalamus? Front Hum Neurosci. 2023; 17: 1271046. DOI: 10.3389/fnhum.2023.1271046
- Rajan R, Anandapadmanabhan R, Vishnoi A, et al. Essential Tremor and Essential Tremor Plus Are Essentially Similar Electrophysiologically. Mov Disord Clin Pract. 2024; 11: 136–142. DOI: 10.1002/mdc3.13941
- Berry DS, Hernandez N, Clark LN, Louis ED. Lack of Familial Aggregation of the “Essential Tremor-Plus” Phenotype in Familial Essential Tremor. Neuroepidemiology. 2022; 56: 373–379. DOI: 10.1159/000526278
- Gionco JT, Hartstone WG, Martuscello RT, Kuo SH, Faust PL, Louis ED. Essential Tremor versus “ET-plus”: A Detailed Postmortem Study of Cerebellar Pathology. Cerebellum; 2021. DOI: 10.1007/s12311-021-01263-6
- Iglesias-Hernandez D, Delgado N, McGurn M, Huey ED, Cosentino S, Louis ED. “ET Plus”: Instability of the Diagnosis During Prospective Longitudinal Follow-up of Essential Tremor Cases. Front Neurol. 2021; 12: 782694. DOI: 10.3389/fneur.2021.782694
- Louis ED, Huey ED, Cosentino S. Features of “ET plus” correlate with age and tremor duration: “ET plus” may be a disease stage rather than a subtype of essential tremor. Parkinsonism Relat Disord. 2021; 91: 42–47. DOI: 10.1016/j.parkreldis.2021.08.017
- Pandey S, Bhattad S, Hallett M. The Problem of Questionable Dystonia in the Diagnosis of ‘Essential Tremor-Plus’. Tremor Other Hyperkinet Mov (N Y). 2020; 10: 27. DOI: 10.5334/tohm.539
- Louis ED. “Essential Tremor Plus”: A Problematic Concept: Implications for Clinical and Epidemiological Studies of Essential Tremor. Neuroepidemiology. 2020; 54: 180–184. DOI: 10.1159/000502862
- Hopfner F, Buhmann C, Classen J, et al. Tips and tricks in tremor treatment. J Neural Transm (Vienna); 2024. DOI: 10.1007/s00702-024-02806-x
- Prasad S, Rajan A, Ingalhalikar M, Bharath RD, Saini J, Pal PK. Probabilistic Tractography-Based Tremor Network Connectivity in Tremor Dominant Parkinson’s Disease and Essential Tremor plus. Brain Connect. 2024; 14: 340–350. DOI: 10.1089/brain.2023.0066
- Paparella G, Angelini L, Margiotta R, et al. Insight into the Relationship Between Motor and Cognitive Symptoms in Essential Tremor. Cerebellum; 2024. DOI: 10.1007/s12311-024-01704-y
- Vidailhet M. Essential tremor-plus: a temporary label. Lancet Neurol. 2020; 19: 202–203. DOI: 10.1016/S1474-4422(19)30442-9
- Louis ED. Rising Problems with the Term “ET-plus”: Time for the Term Makers to Go Back to the Drawing Board. Tremor Other Hyperkinet Mov (N Y). 2020; 10: 28. DOI: 10.5334/tohm.555
- Louis ED, Bain PG. Problems and controversies in tremor classification. J Neurol Sci. 2022; 435: 120204. DOI: 10.1016/j.jns.2022.120204
- Gironell A. Essential tremor: are we just splitting hairs? Non-motor symptoms and essential tremor-plus. Rev Neurol. 2023; 76: 391–398.
- Sun Q, He R, Huang H, et al. Age and Sex Affect Essential Tremor (ET) Plus: Clinical Heterogeneity in ET Based on the National Survey in China. Aging Dis. 2023; 14: 1360–1373. DOI: 10.3389/fnagi.2022.1048961
- Lenka A, Pandey S. Essential Tremor: Five New Things. Neurol Clin Pract. 2022; 12: 183–186. DOI: 10.1212/CPJ.0000000000001145
