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Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia Cover

Multichannel Electromyographic Mapping to Optimize OnabotulinumtoxinA Efficacy in Cervical Dystonia

Open Access
|Aug 2012

Figures & Tables

tre-02-91-598-1-g001.jpg
Figure 1.

Mean Percentage Change in Total Toronto Western Spasmodic Torticollis Scale (TWSTRS) and Subscores in Patients Treated with Multichannel and Single-Channel Electromyographic Botulinum Toxin Injections.

Multichannel electromyographic mapping was associated with improved outcome in all subscales and total TWSTRS scores, although it only reached statistical significance in the disability susbcale.

tre-02-91-598-1-g002.jpg
Figure 2.

Mean and Median Change in Total Toronto Western Spasmodic Torticollis Scale, using Multichannel and Single-Channel Electromyographic Technique

(mean value, dotted line; median value, solid line).

Table 1.

Mean and Median Point Change and Mean Percentage Improvement in Total TWSTRS and TWSTRS Subscores in Patients Treated with Both Multichannel and Single-Channel Electromyography

Multichannel EMG: Mean Point Change±SD (mean percentage change)Multichannel EMG: Median Point Change (±IQR)Single-channel EMG: Mean Point Change±SD (mean percentage change)Single-channel EMG: Median Point Change±IQRp-Value
Total TWSTRS13.44±9.95(23.5%)8.5 (±16.25)5.1 ±9.73(9%)3.5 (±12)p = 0.11
TWSTRS severity5.33±4.79(24.7%)4 (±5)2.33 (±2.87)(11.9%)1 (±4)p = 0.06
TWSTRS disability2.77±2.38(16.1%)3 (±2)1.33 (±4.82)(4.9%)1(± 4)p = 0.04
TWSTRS pain2.88±3.67(19.7%)2.25 (±5.25)1.41 (±3.48)(15.5%)1.5(±1.75)p = 0.26
Mean number of neurotoxin units injected231216p = 0.90

[i] Abbreviations: EMG, electromyography; IQR, interquartile range; SD, standard deviation; TWSTRS, Toronto Western Spasmodic Torticollis Scale.

[ii] Mean values given as SD; median values as IQR.

DOI: https://doi.org/10.5334/tohm.93 | Journal eISSN: 2160-8288
Language: English
Submitted on: Feb 8, 2012
Accepted on: Apr 30, 2012
Published on: Aug 28, 2012
Published by: Columbia University Libraries/Information Services
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2012 Camilla Kilbane, Jill Ostrem, Nicholas Galifianakis, Jamie Grace, Leslie Markun, Graham A. Glass, published by Columbia University Libraries/Information Services
This work is licensed under the Creative Commons License.