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Microlesion Effect Induced by Electrode Implantation in the Posteroventral Globus Pallidus Interna for Severe Dystonic Tics Cover

Microlesion Effect Induced by Electrode Implantation in the Posteroventral Globus Pallidus Interna for Severe Dystonic Tics

Open Access
|Jan 2024

Figures & Tables

Table 1

DBS coordinates and programming parameters.

DBS COORDINATESXYZAC-PC ANGLECENTER LINE ANGLE
Left pvlGPi20.5 mm left4.0 mm anterior7.0 mm inferior60.3°10.1°
Right pvlGPi21.0 mm right4.0 mm anterior5.5 mm inferior60.5°11.1°
tohm-14-1-837-g1.png
Figure 1

Pre- and postoperative imaging and clinical course. Fast gray matter acquisition T1 inversion recovery magnetic resonance imaging sequences (oblique coronal and axial) to plan lead positioning preoperatively and computed tomography scans (coronal and axial) to evaluate lead placement postoperatively in the (A) left posteroventral globus pallidus interna (pvlGPI) and (B) right pvlGPI. (C) Change in blepharospasm-like tic frequency from before surgery to 6-months after bilateral pvlGP deep brain stimulation.

Table 2

The stimulation parameters at each visit. Stimulation areas and amplitudes were gradually increased.

TIME POINTLEFTRIGHT
CATHODE (AMPLITUDE (mA))ANODEPW (µsec)FREQUENCY (Hz)CATHODE (AMPLITUDE (mA))ANODEPW (µsec)FREQUENCY (Hz)
1 mo2 (1.5)Case6013010 (1.5)Case60130
2 mo2 (1.8)Case6013010 (1.8)Case60130
3 mo1 (0.3), 2 (1.5)Case601309 (0.3), 10 (1.5)Case60130
4 mo1 (0.7), 2 (1.6)Case601359a (0.5), 9c (0.3), 10a (0.7), 10b (0.3), 10c (0.3)Case60135
5 mo1 (0.7), 2 (1.6), 3 (0.5)Case601359a (0.5), 9c (0.3), 10a (0.7), 10b (0.3), 10c (0.3)Case60135
6 mo1 (0.7), 2 (1.6), 3 (0.5)Case601359a (0.5), 9c (0.3), 10a (0.7), 10b (0.3), 10c (0.3), 11 (0.5)Case60135
DOI: https://doi.org/10.5334/tohm.837 | Journal eISSN: 2160-8288
Language: English
Submitted on: Oct 31, 2023
Accepted on: Jan 3, 2024
Published on: Jan 18, 2024
Published by: Ubiquity Press
In partnership with: Paradigm Publishing Services
Publication frequency: 1 issue per year

© 2024 Galih Indra Permana, Takashi Morishita, Hideaki Tanaka, Hitoshi Iida, Shinsuke Fujioka, Hiroshi Abe, published by Ubiquity Press
This work is licensed under the Creative Commons Attribution 4.0 License.