Video 1
Gait examination. Showing difficulty in initiation of gait with multiple stuttering of steps associated dance-like bilateral upper limb movements. The gait is broad base with hesitant steps with difficulties in turning.
Video 2
Leg movements in other tasks. The subject is performing complicated coordinated motor activities with his lower limbs while lying down like cycling in midair or drawing numbers in the air.
Figure 1
1A–1E: T2 FLAIR MR image showing diffuse bilateral white matter hyperintensities involving bilateral centrum semiovale, periventricular regions, splenium and forceps major, sparing frontal white and deep grey matter, brainstem and cerebellum. 1F–1H: T2 FLAIR images in patient’s brother with similar changes, albeit to a lesser extent. 1I–1J: T2 sagittal MR image shows corpus callosal body and splenial involvement along with parieto-occipital subcortical involvement. 1K–1L: Diffusion weighted imaging shows faint DW restriction in periventricular area with shine through on ADC (apparent diffusion coefficient) map.